Displaying drugs 13451 - 13475 of 14021 in total
Remtolumab
Remtolumab is under investigation in clinical trial NCT02433340 (Phase 2, Multicenter, Open-Label Extension (OLE) Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study).
Investigational
Matched Description: … Remtolumab is under investigation in clinical trial NCT02433340 (Phase 2, Multicenter, Open-Label Extension ... (OLE) Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study …
SEP-363856
SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Description: … Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug ... SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. ... initial clinical study has shown this drug may be effective against both positive and negative symptoms of …
Dolcanatide
Dolcanatide has been investigated in Exposure.
Investigational
Matched Description: … Dolcanatide has been investigated in Exposure. …
Melarsomine
Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.
Experimental
Vet approved
Matched Iupac: … N2-(4-{bis[(2-aminoethyl)sulfanyl]arsanyl}phenyl)-1,3,5-triazine-2,4,6-triamine …
Matched Description: … for use in dogs with late-stage infection. ... It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved …
Matched Description: … for use in dogs with late-stage infection. ... It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved …
Fleroxacin
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.
Experimental
Matched Iupac: … 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Fleroxacin is not an inhibitor of CYP1A2.[A39048] ... It strongly inhibits the DNA-supercoiling activity of DNA gyrase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Fleroxacin is not an inhibitor of CYP1A2.[A39048] ... It strongly inhibits the DNA-supercoiling activity of DNA gyrase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
IRX-5183
Investigational
Matched Iupac: … 4-(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-amido)-2,6-difluorobenzoic …
FK-960
Investigational
Thiostrepton
Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class.
Vet approved
Matched Iupac: … 2-[({2-[(11E)-37-(butan-2-yl)-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-6,9,16,23,38,41,44,47,59-nonahydroxy ... 51-yl]-1,3-thiazol-4-yl}(hydroxy)methylidene)amino]-N-[1-(C-hydroxycarbonimidoyl)eth-1-en-1-yl]prop-2- ... 7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.2²⁹,³².1²,⁵.1¹²,¹⁵.1¹⁹,²².1³¹,³⁵.1⁵⁴,⁵⁷.0¹,⁵³]tetrahexaconta-2( …
Matched Description: … Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes ... Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide …
Matched Description: … Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes ... Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide …
Amelubant
Investigational
Matched Iupac: … ethyl N-(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)phenyl]methoxy}benzenecarboximidoyl …
Pafuramidine
Pafuramidine, a prodrug of furamidine, currently has orphan status for Pneumocystis jiroveci pneumonia.
Investigational
Matched Iupac: … N-methoxy-4-{5-[4-(N-methoxycarbamimidoyl)phenyl]furan-2-yl}benzene-1-carboximidamide …
Matched Description: … Pafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia …
Matched Description: … Pafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia …
Tucotuzumab celmoleukin
Tucotuzumab celmoleukin is under investigation in clinical trial NCT00016237 (Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not Responded to Previous Treatment).
Investigational
Matched Description: … Tucotuzumab celmoleukin is under investigation in clinical trial NCT00016237 (Interleukin-2 Combined ... With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not …
Sacubitrilat
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Iupac: … (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-(3-carboxypropanamido)-2-methylpentanoic acid …
Matched Description: … A metabolite of LCZ696 with neprilysin inhibitory activity. …
Matched Description: … A metabolite of LCZ696 with neprilysin inhibitory activity. …
Androstenedione
A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.
Experimental
Illicit
Matched Description: … A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal …
Cagrilintide
Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor).
Investigational
Matched Description: … Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With ... Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema …
Methcathinone
Methcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology).
Investigational
Matched Iupac: … 2-(methylamino)-1-phenylpropan-1-one …
Matched Description: … Methcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology …
Matched Description: … Methcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology …
Digitoxigenin
Digitoxigenin is a cardenolide which is the aglycon of digitoxin.
Experimental
Matched Iupac: … 11aR)-3a,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2- …
Matched Description: … Digitoxigenin is a cardenolide which is the aglycon of digitoxin. …
Matched Description: … Digitoxigenin is a cardenolide which is the aglycon of digitoxin. …
Gisadenafil
Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
Investigational
Matched Iupac: … 5-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]pyridin-3-yl}-3-ethyl-2-(2-methoxyethyl)-2H,6H,7H-pyrazolo …
Matched Description: … Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. …
Matched Description: … Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. …
Napabucasin
Napabucasin has been investigated for the treatment of Colorectal Carcinoma.
Investigational
Matched Iupac: … 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione …
Matched Description: … Napabucasin has been investigated for the treatment of Colorectal Carcinoma. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Napabucasin has been investigated for the treatment of Colorectal Carcinoma. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cerlapirdine
Cerlapirdine has been investigated for the treatment of Alzheimer Disease.
Investigational
Matched Description: … Cerlapirdine has been investigated for the treatment of Alzheimer Disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
PG-701
Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (1S,2S,4S,5S,7R,8R,9S,11S,13R)-8,13-dihydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo[11.7.0.0 …
Matched Description: … Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis. …
Matched Description: … Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis. …
Glyceryl Trierucate
Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.
Investigational
Matched Iupac: … 1,3-bis[(13Z)-docos-13-enoyloxy]propan-2-yl (13Z)-docos-13-enoate …
Matched Description: … Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy. …
Matched Description: … Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy. …
AC-430
AC430 has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (4-fluorophenyl)({4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl})methanol …
Matched Description: … AC430 has been investigated for the treatment of Rheumatoid Arthritis. …
Matched Description: … AC430 has been investigated for the treatment of Rheumatoid Arthritis. …
Surinabant
Surinabant has been investigated for the treatment of Smoking Cessation.
Investigational
Matched Description: … Surinabant has been investigated for the treatment of Smoking Cessation. …
TZ-101
TZ-101 composes of GDP-L-fucose and fucosyltransferase VI
Investigational
Matched Description: … TZ-101 composes of [GDP-L-fucose] and fucosyltransferase VI …
Perifosine
Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition.
Investigational
Displaying drugs 13451 - 13475 of 14021 in total