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Displaying drugs 1451 - 1475 of 1970 in total
Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome.
Experimental
Matched Synonyms: … D-Homopantothenic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational
Matched Synonyms: … 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione …
Matched Iupac: … 1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-Nim-benzyl-histidyl-L-leucyl-L-arginyl-L-proline ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Description: … to their capacity to reduce LH levels and the concentration of sex steroids. ... GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due ... implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate
Matched Salts name: … Histrelin acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Name: … N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Experimental
Matched Name: … 1-(5-phospho-D-ribosyl)-ATP …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … 2,5-Dideoxy-2,5-Imino-D-Glucitol …
Experimental
Matched Name: … Cytidine-5'-diphospho-beta-D-xylose …
Experimental
Matched Name: … 5-Thio-a/B-D-Mannopyranosylamine …
Experimental
Matched Name: … 1,6-DI-O-PHOSPHONO-D-MANNITOL …
Experimental
Matched Name: … D-phenylalanyl-N-benzyl-L-prolinamide …
Experimental
Matched Name: … N-(biphenyl-4-ylsulfonyl)-D-leucine …
Experimental
Matched Name: … AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH …
Experimental
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside ... diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-β-D-ribofuranosyl …
Matched Name: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... {[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl …
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … 17-alpha-Ethinylestradiol 3-cyclopentyl ether …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Dimepheptanol is under investigation in clinical trial NCT00218127 (Treatment of Opioid/heroin Dependence: Comparison of Three Medication Dosing Regimens).
Investigational
Matched Synonyms: … .-(2-(dimethylamino)propyl(-.alpha.-ethyl-.beta.-phenyl- …
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
Experimental
Matched Name: … 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide …
Experimental
Matched Name: … N-[Tosyl-D-Prolinyl]Amino-Ethanethiol …
Experimental
Matched Name: … AC-(D)Phe-pro-borolys-OH …
Experimental
Matched Name: … N-[(4-methoxyphenyl)sulfonyl]-D-alanine …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … [A186215,A186218] It also means that opioid-dependent patients do not experience sedation or euphoria ... who require larger and more frequent doses. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... Bupensan Duo 8 mg/2 mg-Sublingualtabletten ... Bupensan Duo 2 mg/0,5 mg-Sublingualtabletten …
Matched Salts name: … Buprenorphine hydrochloride
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Synonyms: … Benzo[d]isoxazol-3-yl-methanesulfonamide …
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZONISAMIDE DOC GENERICI …
Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.
Experimental
Matched Synonyms: … Potassium antimonyl D-tartrate …
Matched Description: … It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects. …
Displaying drugs 1451 - 1475 of 1970 in total