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Displaying drugs 1501 - 1525 of 1543 in total
Experimental
Matched Name: … (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one …
Matched Iupac: … (6S)-1-chloro-3-[(4-fluorophenyl)methoxy]-6-(pyrrolidine-1-carbonyl)-4H,6H-pyrrolo[1,2-a]pyrazin-4-one …
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... FDA approved for patients who are intolerant and/or resistant to two or more tyrosine kinase inhibitors ... Most recently, in October 2012, omacetaxine mepesuccinate was marketed under the brand name Synribo and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … , in buffer solutions, and in fertilizers and explosives. ... that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and ... A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Dextrose and Electrolyte No. 75 ... Ringers and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Drugs that are Mainly Renally Excreted …
Matched Products: … Kcl Solution A 20% ... APO-K TABLET 600 mg ... APO-K TABLET 600MG (S/R) …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … ’s and Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORUBICIN AU 2MG/ML 10MG ... DOXORUBICIN AU 2MG/ML 50MG ... DOXORUBICIN AU 2MG/ML200MG …
Experimental
Matched Name: … (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL …
Matched Iupac: … (1S,2R,5S)-5-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-2-(2,4,5-trifluorophenyl …
Experimental
Matched Name: … 8-Benzyl-2-Hydroxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One …
Matched Iupac: … (2S)-8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H,3H-imidazo[1,2-a]pyrazin-3 …
Experimental
Matched Name: … (5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN …
Matched Iupac: … 5-(3-bromophenyl)-7-{[(pyridin-4-yl)methyl]amino}-1H-8lambda5-pyrazolo[1,5-a]pyrimidin-8-ylium …
Experimental
Matched Name: … (2S)-1-(Dimethylamino)-3-(4-{[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]amino}phenoxy)-2-propanol …
Matched Iupac: … (2S)-1-(dimethylamino)-3-{4-[(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]phenoxy}propan …
Experimental
Matched Name: … 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol …
Matched Iupac: … 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol …
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … ) routes and has been used in various biomedical applications, including dentistry, cardiac surgery, ... [F2977] This drug was initially approved by the US FDA in 1985, and has been approved for various ... and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Drugs that are Mainly Renally Excreted …
Matched Products: … N/a ... DOMI INJECTION 5MG (1ML AMP) ... DOMI INJECTION 5MG (5ML AMP) …
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … It attains high serum levels and is excreted quickly via the urine. ... A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Products: … CEFAZOLINA ACS DOBFAR ... Kefzol Add-vantage Inj 1gm/vial ... Kefzol Add-vantage Inj 500mg/vial …
Experimental
Matched Name: … N-{3-[(7ar,12as,12bs)-7-Oxo-1,3,4,6,7,7a,12a,12b-Octahydroindolo[2,3-a]Quinolizin-12(2h)-Yl]Propyl}Propane …
Matched Iupac: … N-{3-[(12bS)-7-oxo-1H,2H,3H,4H,6H,7H,12H,12bH-indolo[2,3-a]quinolizin-12-yl]propyl}propane-2-sulfonamide …
Experimental
Matched Name: … 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE …
Matched Iupac: … 2,2,2-trifluoro-1-(5-{3-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-7-carbonyl}thiophen-2-yl)ethane-1,1 …
Investigational
Matched Synonyms: … -7-hydroxy-10,13-dimethyl-3-((4-((pyridin-3- ylmethyl)amino)butyl)amino)hexadecahydro-1H-cyclopenta[a] …
Matched Categories: … Toxic Actions ... Compounds used in a research, industrial, or household setting …
Experimental
Matched Name: … 1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-(5-PYRROLIDIN-2-YL-1H-PYRAZOL-3-YL)-UREA …
Matched Iupac: … 3-[(9bS)-5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-9-yl]-1-{5-[(2S)-pyrrolidin-2-yl]-1H-pyrazol-3-yl}urea …
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched International brands: … Atecard-AM
Matched Description: … associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... Amlodipine is commonly used in the treatment of high blood pressure and angina. …
Matched Mixtures name: … SUB-ZERO 5MG/160MG FILM TABLET,TABLET, 28 ADET ... SUB-ZERO 10MG/160MG FILM TABLET ,TABLET, 28 ADET ... AMLODIPINE and VALSARTAN …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... aliskiren and amlodipine ... losartan and amlodipine ... benazepril and amlodipine …
Matched Products: … A-B VASK 5 ... A-B VASK 10 ... AMLODIPINA AWP
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes ... [A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark ... stroke, has become a leading cause of death in high-income countries and a major cause of morbidity …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Alimentary Tract and Metabolism ... rosuvastatin and valsartan ... rosuvastatin and ramipril ... rosuvastatin and ezetimibe ... rosuvastatin and amlodipine …
Matched Products: … Ag-rosuvastatin ... Apo-rosuvastatin ... Ach-rosuvastatin …
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … various cancers such as lung, cervical and ovarian cancer. ... Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Products: … DARITEX-A
Experimental
Matched Name: … 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN …
Matched Iupac: … 4-[(3aS,4R,7R,8aS,8bR)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-7-hydroxy-1,3-dioxo-decahydropyrrolo[3,4-a] …
Experimental
Matched Name: … ,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A] …
Matched Iupac: … 9bS,11aR)-11a-{2-[(3,5-difluorophenyl)methoxy]ethyl}-1-hydroxy-9a-methyl-hexadecahydro-1H-cyclopenta[a] …
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A
Matched Description: … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... of breath and the coughing up of blood. ... Acinetobacter baumanii and Pseudomonas aeruginosa. …
Matched Categories: … cefepime and amikacin ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted …
Matched Products: … APALIN 250MG INJECTION (2ML AMP) ... APALIN 500MG INJECTION (2ML AMP) ... APALIN 100MG INJECTION (2ML AMP) …
Experimental
Matched Name: … 4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL …
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … Taxol A ... ABI-007 COMPONENT PACLITAXEL …
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound ... Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in ... Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... paclitaxel and encequidar ... Antineoplastic and Immunomodulating Agents ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Aj-paclitaxel ... Apo-paclitaxel Injectable …
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … API ... Mucus proteinase inhibitor …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-D][1,3]Thiazolo[3,2-a]Pyrimidin …
Displaying drugs 1501 - 1525 of 1543 in total