Displaying drugs 1676 - 1700 of 2256 in total
IMM101
IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039]. Studies with IMM-101 showed the vaccine’s ability to stimulate cancer patients’ immune systems to help...
Investigational
Matched Description: … 1500 participants to evaluate the vaccine’s protective effects on cancer patients from severe COVID-19 …
Birabresib
Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Investigational
Matched Iupac: … chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9- …
Perospirone
Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as...
Experimental
Palazestrant
Palazestrant is under investigation in clinical trial NCT06016738 (OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer).
Investigational
Flunisolide acetate
Experimental
Matched Iupac: … 2-[(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo …
Acetyl Dithranol
Experimental
Matched Iupac: … 2-(1,8-dihydroxy-9-oxo-9,10-dihydroanthracen-2-yl)acetic acid …
Diphenyleneiodonium
An NADPH oxidase 2 (NOX2) inhibitor.
Investigational
Matched Iupac: … 8lambda3-iodatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-8-ylium …
Matched Salts cas: … 3895-92-9 …
Matched Salts cas: … 3895-92-9 …
Pirlindole
This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug.
Pirlindole is a...
Experimental
Matched Iupac: … 12-methyl-1,4-diazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-9(16),10,12,14-tetraene …
CTX120
CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Investigational
Vitespen
Investigational
Tabituximab barzuxetan yttrium Y-90
A version of tabituximab barzuxetan radiolabeled with yttrium-90.
Investigational
Altrenogest
Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals.
Vet approved
Omburtamab I-131
Investigational
Exatecan
Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Investigational
Matched Iupac: … (10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.0^{2,14}.0 …
Matched Salts cas: … 197720-53-9 …
Matched Salts cas: … 197720-53-9 …
TACRINE(8)-4-AMINOQUINOLINE
Experimental
Matched Iupac: … N1-(quinolin-4-yl)-N8-(1,2,3,4-tetrahydroacridin-9-yl)octane-1,8-diamine …
D-Eritadenine
Experimental
Matched Iupac: … (2R,3R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxybutanoic acid …
Besifovir
Investigational
Matched Iupac: … ({1-[(2-amino-9H-purin-9-yl)methyl]cyclopropoxy}methyl)phosphonic acid …
lambda-bis(2,2'-bipyridine)imidazole osmium (II)
Experimental
Matched Iupac: … ,1'(9'),2,2',4,4',6,6',10,10',12,12'-dodecaene-8,8-bis(ylium) ... 7lambda4,7'lambda4,9lambda4,9'lambda4-tetraaza-8-osma-8,8'-spirobi[tricyclo[7.4.0.0^{2,7}]tridecane]-1(9) …
7-methyl-GpppA
Experimental
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl] ... hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9- …
8-azaguanine
8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
Experimental
Displaying drugs 1676 - 1700 of 2256 in total