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Displaying drugs 1676 - 1700 of 1813 in total
Experimental
Matched Name: … (2Z)-1-(5-Chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-tetrazol-5-yl)-2-propen-1-one …
Matched Iupac: … (2Z)-1-(5-chloro-1H-indol-3-yl)-3-hydroxy-3-(1H-1,2,3,4-tetrazol-5-yl)prop-2-en-1-one …
Experimental
Matched Name: … [2-(1-amino-2-hydroxy-propyl)-4-(1H-indol-3-ylmethylene)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetaldehyde …
Matched Iupac: … 2-[(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-[(1H-indol-3-yl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol …
Experimental
Matched Name: … 2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-2-[(2R)-2-ethanesulfonamido-3-(5-propoxy-1H-indol-3-yl)propanamido …
Experimental
Matched Name: … (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-({5-[(1E)-2-(pyridin-4-yl)ethenyl]pyridin-3-yl}oxy)propan-2-amine …
Experimental
Matched Name: … [2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid …
Matched Iupac: … 2-{2-[(1R,2S)-1-amino-2-hydroxypropyl]-4-[(4-fluoro-1H-indol-3-yl)methyl]-5-hydroxy-1H-imidazol-1-yl} …
Experimental
Matched Name: … (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID …
Matched Iupac: … (2S)-3-(1-{[2-(2-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-1H-indol-5-yl)-2-ethoxypropanoic acid …
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Description: … [L11347] Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants ... Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption ... The discovery and research of this drug began in the early 1990s, after the intravenous administration …
Matched Mixtures name: … Ezetimib/Simvastatin STADA 10 mg/10 mg Tabletten ... Ezetimib/Simvastatin STADA 10 mg/20 mg Tabletten ... Ezetimib/Simvastatin STADA 10 mg/40 mg Tabletten …
Matched Categories: … simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... bempedoic acid and ezetimibe ... rosuvastatin and ezetimibe …
Matched Products: … EZETIMIB STADA 10MG ... Ezetimib STADA 10 mg Tabletten …
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[IL27 (interleukin 27,IL27p28, IL27A)], Homo sapiens monoclonal antibody
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like [morphine] and
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … FENTANYL STADA 100UG/H MAT ... FENTANYL STADA 12UG/H MATR ... FENTANYL STADA 25UG/H MATR …
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
Matched Products: … DILTIAZEM STADA 180MG ... DILTIAZEM STADA 90MG RET ... DILTIAZEM STADA 120MG RET …
Experimental
Matched Name: … 5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide …
Matched Iupac: … 5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N,2,4-trimethyl-1H-pyrrole-3-carboxamide …
Experimental
Matched Name: … 3,4-Dihydroxy-5-(4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-pyrrolidinyl]methyl dihydrogen phosphate
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Description: … is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine ... Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker ... Hyperpolarization-activated Cyclic Nucleotide-gated Channel Antagonists …
Matched Products: … Ivabradin Stada 5 mg Filmtabletten ... Ivabradin Stada 7,5 mg Filmtabletten …
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... vulgaris. ... Spironolactone is a potassium-sparing diuretic. …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Potassium-Sparing Diuretics …
Matched Products: … SPIRONOLACTON STADA 50MG ... SPIRONOLACTON STADA 100MG …
Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and
Matched Categories: … Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … ACYCLOVIR 200 STADA ... ACYCLOVIR 400 STADA ... ACYCLOVIR 800 STADA
Experimental
Matched Name: … (5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL …
Matched Iupac: … [5-(3-{5-[(piperidin-1-yl)methyl]-1H-indol-2-yl}-1H-indazol-6-yl)-2H-1,2,3-triazol-4-yl]methanol …
Experimental
Matched Name: … (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and
Matched Mixtures name: … Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Candesartan STADA 4 mg Tabletten ... Candesartan STADA 8 mg Tabletten ... Candesartan STADA 16 mg Tabletten …
Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Description: … Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... fibrillation and flutter. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …
Matched Products: … FLECAINIDACET STADA 100MG …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying ... (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Dimethylfumarat STADA 120 mg magensaftresistente Hartkapseln ... Dimethylfumarat STADA 240 mg magensaftresistente Hartkapseln …
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched International brands: … You Care
Matched Description: … Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. ... Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain ... Imiquimod does not cure warts, and new warts may appear during treatment. …
Matched Categories: … Skin and Mucous Membrane Agents …
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically ... The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Teriflunomid STADA 14 mg Filmtabletten …
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB STADA 30MG ... ETORICOXIB STADA 60MG ... ETORICOXIB STADA 90MG …
Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Matched Description: … It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than ... [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a ... positive results obtained from 3 double-blind, randomized, controlled clinical trials known as FAST 1, 2, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze …
Displaying drugs 1676 - 1700 of 1813 in total