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Displaying drugs 1676 - 1700 of 1909 in total

Dasatinib

Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … ) gene transcribe the chimeric protein BCR-ABL. ... pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds ... Protein Kinase Inhibitors …
Matched Products: … DASİKAM 20 MG FİLM KAPLI TABLET ... DASİKAM 50 MG FİLM KAPLI TABLET ... DASİKAM 70 MG FİLM KAPLI TABLET …

Tolterodine

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOLTEX 2 MG FILM TABLET, 28 ADET ... TOLTEX FİLM 1 MG TABLET , 28 ADET ... URIDYN 1 MG FILM TABLET ,28 ADET …

Famciclovir

Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … FAMVIR 250 MG FILM TABLET, 21 ADET ... VIRMOL 125 MG FILM KAPLI TABLET, 14 ADET ... VIRMOL 500 MG FILM KAPLI TABLET, 14 ADET …

Lacosamide

Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved ... Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium …
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … VIMPAT 50 MG (FILM-COATED TABLETS) ... VIMPAT 100 MG (FILM-COATED TABLETS) ... BENVIDA 50 MG FILM KAPLI TABLET, 14 ADET …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Letara Film Coated Tablet 2.5mg ... Trozet Film Coated Tablet 2.5mg ... FEMARA 2.5MG FILM-COATED TABLET …

Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon has not been shown to produce dependence and has shown no potential for abuse. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … RAMELDA 8 MG FILM KAPLI TABLET,30 ADET ... RAMELDA 8 MG FILM KAPLI TABLET,10 ADET ... ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET …

Dexibuprofen

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … IBUDEX 400 FILM TABLET, 10 ADET ... IBUDEX 400 FILM TABLET, 30 ADET ... IBUDEX 400 MG FILM TABLET, 20 ADET …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … URSOKOL 250 MG FILM TABLET,100 ADET ... URSOKOL 500 MG FILM TABLET,100 ADET ... URSOKOL 750 MG FİLM TABLET, 50 ADET …

Varenicline

Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Chantix, has been associated with seizures and that some patients who drink while taking the drug may ... In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Products: … CHAMPIX 0.5MG FILM-COATED TABLETS ... CHAMPIX 1.0MG FILM-COATED TABLETS ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …

Clesrovimab

Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus f protein …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …

Teropavimab

Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … KARDORITM PLUS 10 MG/25 MG FILM TABLET ,FILM TABLET, 30 ADET ... Cosyrel 5mg/5mg film-coated tablets ... Cosyrel 5mg/10mg film-coated tablets …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... ramipril and bisoprolol ... bisoprolol and thiazides ... perindopril and bisoprolol …
Matched Products: … Concor 5mg Film coated Tablet ... ADROTEN FILM-COATED TABLET 5MG ... Concor 10mg Film coated Tablet …

Zolmitriptan

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... It is currently available in both tablet and nasal spray forms.[L12978] ... [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET ... MIGTERA 5 MG FİLM TABLET, 6 ADET …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … MOLAX-M FILM COATED TABLET ... DOMPERIDON - CT 10MG FILMT ... MOTILIUM 10 MG FILM TABLET, 21 ADET …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Categories: … moxonidine and diuretics …
Matched Products: … MOXONIDIN - CT 0.2MG FILM ... MOXONIDIN - CT 0.3MG FILM ... MOXONIDIN - CT 0.4MG FILM …

Piracetam

Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … KNOWFUL FILM COATED TABLET 800MG ... Ceretam 800mg Film-Coated Tablet ... KNOFUL (FILM COATED TABLET 800 MG) …

Ofloxacin

A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … OFCIN FILM COATED TABLET 200MG ... OFCIN FILM COATED TABLET 400MG ... OFCIN FILM COATED TABLET 400 mg …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … FILUT® TABLETAS ... FILUT NX® SOLUCION ... FILUT® TERBINAFINA AL 1% …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing and ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … Tagrisso Film-Coated Tablet 40mg ... Tagrisso Film-Coated Tablet 80mg ... TAGRİSSO 40 MG FİLM KAPLI TABLET …

Fimasartan

Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and ... Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand …
Matched Mixtures name: … ARAHKOR - PRE …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... fimasartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... fimasartan and amlodipine ... rosuvastatin and fimasartan …
Matched Products: … Kanarb Film-Coated Tablets 60mg ... Kanarb Film-Coated Tablets 120mg ... KANARB®PLUS FILM COATED TABLETS 60 MG/12.5 MG …

Diosmin

Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... Diosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) ... Davmorid Film Coated Tablet ... DIOSPER FILM COATED TABLET …
Matched Products: … DAFLON FILM-COATED TABLET 1000 mg ... RUVENTIN FILM COATED TABLET 500MG ... DAFLON 500 MG FILM TABLET, 60 ADET …

Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …

Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen

Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …

Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... capsular antigens of *Streptococcus pneumoniae* serotype 10A individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein …

Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... capsular antigens of *Streptococcus pneumoniae* serotype 12F individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein …
Displaying drugs 1676 - 1700 of 1909 in total