Displaying drugs 1676 - 1700 of 2030 in total
Esmolol
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Matched Products: … Esmolol Hydrochloride In Sodium Chloride …
Matched Products: … Esmolol Hydrochloride In Sodium Chloride …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Melanoma antigen recognized by T-cells 1
Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery).
Investigational
Matched Name: … Melanoma antigen recognized by T-cells 1 …
Matched Description: … Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery ... Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery ... Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Paclitaxel
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound ... paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Lanimostim
Investigational
Matched Synonyms: … 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced) …
Begelomab
Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … DIPEPTIDYLPEPTIDASE 4, DIPEPTIDYLPEPTIDASE IV, ADENOSINE DEAMINASE COMPLEXING PROTEIN 2, ADCP2, TP103, T CELL …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
KITE-222
Investigational
Matched Synonyms: … An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and ... Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human …
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and ... Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human …
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human intercellular adhesion molecule icam-1) (human monoclonal bi-505 .gamma ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … in a Chinese hamster ovary cell line. ... Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … in a Chinese hamster ovary cell line. ... Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
BI-836858
Investigational
Matched Synonyms: … Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Maplirpacept
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Retlirafusp alfa
Investigational
Matched Synonyms: … isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with ... Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Angelica archangelica root
Angelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Archangelica Officinalis Root Extract …
Yohimbine
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched International brands: … Baron-X …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Oxytocin
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … Dale first identified oxytocin and its uterine contractile properties in 1906. ... and central effects. ... [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Oxytocin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PITOCIN 10 UNIDADES X ML. AMPOLLETAS …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Oxytocin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PITOCIN 10 UNIDADES X ML. AMPOLLETAS …
Colchicine
Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Description: … [L8192] Colchicine is used in the treatment of gout flares and Familial Mediterranean fever,[L8138] and ... [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … colchicine and probenecid …
Matched Products: … COLCHICINA COMPRIMIDO X 0.5 MG …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … colchicine and probenecid …
Matched Products: … COLCHICINA COMPRIMIDO X 0.5 MG …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Cefalotin
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Salts name: … Cefalotin sodium …
Matched Products: … CEFALOTINA (SODICA)1 G FRASCO AMPOLLA …
Matched Products: … CEFALOTINA (SODICA)1 G FRASCO AMPOLLA …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... doses of 125, 25, and 50 mg is approximately 93%. ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ROFECOXIB TABLETAS X 50 MG …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ROFECOXIB TABLETAS X 50 MG …
Insulin-like growth factor II
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Human oligopeptide-24 ... Human insulin-like growth factor II ... Insulin-like growth factor II (human) …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... To perform its biological activities, this growth factor can present some dependence to [somatotropin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... To perform its biological activities, this growth factor can present some dependence to [somatotropin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1676 - 1700 of 2030 in total