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Displaying drugs 151 - 175 of 9336 in total

Besilesomab

Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved

Valrubicin

Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Synonyms: … (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido ... 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino] ... hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate …
Matched Iupac: … -2-yl]oxy}-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate ... 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-4-{[(2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)oxan …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Mixtures name: … NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM ... Clearskin 2 Tinted Blemish Crm ... Sodium Sulfacetamide 10%, Sulfur 2% …
Matched Products: … Postacne Lotion 2% ... Postacne Lotion - 2% ... Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 …
Matched Salts cas: … 1639324-62-1 …
Matched Categories: … Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors …

Hydroxychloroquine

Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Synonyms: … 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline ... 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline ... 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinoline …
Matched Iupac: … 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol …
Matched Description: … A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … PLAQUENIL 200 MG FILM KAPLI TABLET, 60 ADET …

Dihydroergocornine

Dihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects. It is an artificial derivative of the crude extract of ergot and later purified, ergocornine. The formation of dihydroergocornine implies the hydrogenation of the double bonds in the lysergic acid. Dihydroergocornine presents a formula of 9,10...
Approved
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-2-hydroxy-5,8-dioxo-4,7-bis(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0^ ... {2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … [A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl …

Ulmus crassifolia pollen

Ulmus crassifolia pollen is the pollen of the Ulmus crassifolia plant. Ulmus crassifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Salts cas: … 148-72-1 ... 63036-94-2 …
Matched Mixtures name: … E-pilo-1 Oph Soln ... E-pilo 1 Ophthalmic Solution ... Timpilo 2 …
Matched Products: … -carpine 1% ... PILOMANN 1% ... Pilocarpine 1% …

Cefepime

Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ROXIPIME 2 G IV ENJEKSIYON VE INFÜZYON IÇIN TOZ IÇEREN FLAKON ,1 ADET ... Maxipime 2 g - Trockenstechampullen ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …

Methyl nicotinate

Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Betula lenta pollen

Betula lenta pollen is the pollen of the Betula lenta plant. Betula lenta pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Synonyms: … -4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Iupac: … -4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … [A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the …
Matched Products: … PERIOCLINE PERIODONTAL OINTMENT 2% W/W …

Technetium Tc-99m medronate

Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way...
Approved
Matched Salts cas: … 65871-22-9 …

Quercus alba pollen

Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis and treatment of allergic disease to grass pollen. It can be subcutaneously administered to initiate an immune response in case of an allergic reaction. Diagnostic allergenic extracts are primarily indicated for establishing clinical relevance...
Approved
Matched Mixtures name: … 2-oak Mix, Red/white Pollen ... 9 Tree Mix ... 9 Tree Mix …

Voxilaprevir

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Iupac: … (1R,18R,20R,24S,27S,28S)-24-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl …
Matched Description: … Vosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Notably, Vosevi is approved for use in patients with genotypes 1-6 who have been previously treated with …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Palbociclib

Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Synonyms: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H) …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …

Dehydrocholic acid

Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Iupac: … 1R,3aS,3bR,5aS,9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …

Fraxinus americana pollen

Fraxinus americana pollen is the pollen of the Fraxinus americana plant. Fraxinus americana pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Acer saccharinum pollen

Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix …

Lorcaserin

Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Matched Iupac: … (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … MATE 1 Substrates ... MATE 2 Substrates …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …

Levonorgestrel

Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Mixtures name: … PIL KB 1 KOMBINASI ... PIL KB 1 KOMBINASI …
Matched Products: … Option 2 ... KIERD-1 ... VALENOR 2 …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … [A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved

Tioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … 2-Amino 6MP ... 2-Aminopurin-6-thiol ... 2-Amino-6-purinethiol …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 151 - 175 of 9336 in total