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Displaying drugs 151 - 175 of 179 in total
KUR-113
KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.
Investigational
Matched Synonyms: … Fibrin-based agent containing a N-terminally modified parathyroid hormone fragment TGplPTH1-34 …
Matched Description: … KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone …
Matched Description: … KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone …
Palopegteriparatide
Palopegteriparatide is a mPEG conjugated parathyroid hormone 1-34.
Investigational
Matched Synonyms: … Transcon parathyroid hormone (1-34) ... Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino ... cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34)-peptide of parathyroid …
Matched Description: … Palopegteriparatide is a mPEG conjugated parathyroid hormone 1-34. …
Matched Categories: … Parathyroid Hormones and Analogues …
Matched Description: … Palopegteriparatide is a mPEG conjugated parathyroid hormone 1-34. …
Matched Categories: … Parathyroid Hormones and Analogues …
PCO-371
PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).
Investigational
Matched Synonyms: … non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I …
BOS172722
BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment,...
Experimental
1alpha,24S-Dihydroxyvitamin D2
LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol,...
Investigational
Frankincense
Experimental
Evocalcet
Evocalcet has been used in trials studying the treatment of Hyperparathyroidism and Secondary Hyperparathyroidism.
Investigational
Matched Categories: … Anti-Parathyroid Agents …
Boserolimab
Investigational
ABX-PTH
ABX-PTH is a fully human monoclonal antibody generated by Abgenix's technology platform. This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary hyperparathyroidism.
Investigational
Matched Description: … This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary …
Calcium
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
MBX-2109
MBX-2109 is a long-acting parathyroid hormone peptide prodrug under investigation for the treatment of hyperparathyroidism.
Investigational
Matched Description: … MBX-2109 is a long-acting parathyroid hormone peptide prodrug under investigation for the treatment of …
QR-334
QR-334 is under investigation for the treatment of sialorrhea. Sialorrhea is an excess secretion of saliva produced by the salivary glands, resulting in drooling. No pharmaceutical interventions currently exist to treat sialorrhea. The symptom is associated with many diseases including Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease,...
Investigational
NPS-2143
Investigational
PAC-113
PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. In vitro studies demonstrate that it has potent anti-fungal activity against the Candida albicans, including drug-resistant HIV patient isolates. PAC-113 is targeting oral...
Investigational
Colforsin
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Description: … relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland …
Calcitonin porcine
Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in...
Experimental
Matched Description: … Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals …
CTA018
CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D...
Investigational
Royal jelly
Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
AP1081
A transdermal gel containing ethinyl estradiol and norelgestromin being investigated by Antares Pharma for use as a female contraceptive.
Investigational
Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Tasosartan
Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.
Experimental
TAS-108
Investigational
Displaying drugs 151 - 175 of 179 in total