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Displaying drugs 1726 - 1750 of 2451 in total
anti-OX40 antibody BMS 986178
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
Matched Categories: … Immune Checkpoint Inhibitors …
Glutaric Acid
Experimental
Matched Categories: … OAT1/SLC22A6 inhibitors ... OAT3/SLC22A8 Inhibitors …
E-2012
E-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's disease.
Investigational
Matched Categories: … Enzyme Inhibitors ... Gamma Secretase Inhibitors and Modulators …
3-isobutyl-1-methyl-7H-xanthine
Experimental
Matched Categories: … Enzyme Inhibitors ... Phosphodiesterase Inhibitors …
ABT-341
ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different).
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors …
BMS-986115
BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.
Investigational
Matched Categories: … Enzyme Inhibitors ... Gamma Secretase Inhibitors and Modulators …
Arsanilic acid
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Categories: … Enzyme Inhibitors ... Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Potent reversible inhibitor of phenylethanolamine N-methyltransferase.
Experimental
Matched Categories: … Enzyme Inhibitors ... Monoamine Oxidase Inhibitors ... Phenylethanolamine N-Methyltransferase, antagonists & inhibitors …
Olmutinib
Olmutinib is an orally active epidermal growth factor receptor inhibitor used in the treatment of T790M mutation positive non-small cell lung cancer. It is available under the brand name Olita made by Hanmi Pharmaceuticals . Olmutinib was developed by Hanmi Pharmaceuticals and Boehringer Ingelheim. Olmutinib recieved breakthrough therapy designation in...
Investigational
Matched Categories: … Protein Kinase Inhibitors ... Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Difloxacin
Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Vet approved
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Seliciclib
R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex...
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
PF-477736
PF-00477736 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Tenalisib
Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).
Investigational
Matched Categories: … Enzyme Inhibitors ... Phosphoinositide-3 Kinase Inhibitors …
Nemiralisib
Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Olomoucine
Experimental
Matched Categories: … Enzyme Inhibitors ... Cyclin-Dependent Kinases, antagonists & inhibitors …
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors ... Protein-Serine-Threonine Kinases, antagonists & inhibitors …
Retaspimycin
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors ... Protein-Serine-Threonine Kinases, antagonists & inhibitors …
Oclacitinib
Investigational
Vet approved
Matched Categories: … Janus Kinase 1, antagonists & inhibitors ... Janus Kinases, antagonists & inhibitors …
Trebananib
Trebananib is under investigation for the treatment of Ovarian Cancer, Peritoneal Cancer, and Fallopian Tube Cancer. Trebananib has been investigated for the treatment of Cancer, Oncology, Carcinoma, Metastases, and Colon Cancer, among others.
Investigational
Matched Categories: … Growth Inhibitors ... Angiogenesis Inhibitors …
Allosamidin
Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
Experimental
Matched Categories: … Enzyme Inhibitors ... Chitinases, antagonists & inhibitors …
Selonsertib
Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Avidin
Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors …
Acetyldinaline
Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
Investigational
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors …
Fenvalerate
Investigational
Matched Categories: … Enzyme Inhibitors ... Iodide Peroxidase, antagonists & inhibitors …
Solithromycin
Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Displaying drugs 1726 - 1750 of 2451 in total