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Displaying drugs 1801 - 1825 of 2447 in total
K-252a
Experimental
Matched Categories: … Enzyme Inhibitors ... Protein Kinase C, antagonists & inhibitors …
Acumapimod
Acumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Calyculin A
Experimental
Matched Categories: … Enzyme Inhibitors ... Phosphoprotein Phosphatases, antagonists & inhibitors …
Varespladib methyl
Varespladib methyl has been investigated for the treatment of Acute Coronary Syndrome. Studies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.
Investigational
Matched Categories: … Enzyme Inhibitors ... Phospholipase A2 Inhibitors …
Tacedinaline
Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
Investigational
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors …
Beloranib
Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
Investigational
Matched Categories: … Growth Inhibitors ... Angiogenesis Inhibitors …
Nolatrexed
Nolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
Investigational
Matched Categories: … Enzyme Inhibitors ... Thymidylate Synthase, antagonists & inhibitors …
Ridogrel
Ridogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. However, there currently are no clinical indications for preferential use of ridogrel over aspirin.
Experimental
Matched Categories: … Enzyme Inhibitors ... Thromboxane-A Synthase, antagonists & inhibitors …
Rebastinib
Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Talarozole
Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Investigational
Matched Categories: … Enzyme Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …
S-Ethylisothiourea
S-Ethylisothiourea is a nitric oxide synthase inhibitor.
Experimental
Matched Categories: … Enzyme Inhibitors ... Nitric Oxide Synthase, antagonists & inhibitors …
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Categories: … Lipopolysaccharides, antagonists & inhibitors ... Toll-Like Receptor 4, antagonists & inhibitors …
Galeterone
Galeterone has been used in trials studying the treatment of Prostate Cancer.
Investigational
Matched Categories: … Enzyme Inhibitors ... Steroid 17-alpha-Hydroxylase, antagonists & inhibitors …
Dapoxetine
Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (weak) ... Selective Serotonin Reuptake Inhibitors …
TMC-310911
TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections. TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to...
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... HIV Protease Inhibitors …
Islatravir
Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
Investigational
Matched Categories: … Enzyme Inhibitors ... Nucleic Acid Synthesis Inhibitors ... Reverse Transcriptase Inhibitors …
Rosmarinic acid
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Serine Protease Inhibitors ... Aldehyde Reductase, antagonists & inhibitors …
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Categories: … Enzyme Inhibitors ... P-glycoprotein inhibitors …
5-iodotubercidin
Experimental
Matched Categories: … Enzyme Inhibitors ... Adenosine Kinase, antagonists & inhibitors …
Trapidil
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Categories: … Enzyme Inhibitors ... Phosphodiesterase Inhibitors …
Roquinimex
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Categories: … Growth Inhibitors ... Angiogenesis Inhibitors …
Ruboxistaurin
Ruboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase C, antagonists & inhibitors …
Posiphen
Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Investigational
Matched Categories: … Enzyme Inhibitors ... Cholinesterase Inhibitors …
Ricolinostat
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors …
Displaying drugs 1801 - 1825 of 2447 in total