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Displaying drugs 2001 - 2025 of 3013 in total
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
Matched Description: … New Zealand and Canada have also followed suit in recalling the drug. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … (2Z)-2-(benzoylamino)-3-[4-(2-bromophenoxy)phenyl]-2-propenoic acid
Matched Name: … (2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid
Matched Iupac: … (2Z)-3-[4-(2-bromophenoxy)phenyl]-2-(phenylformamido)prop-2-enoic acid
Experimental
Matched Synonyms: … 2'-guanylic acid
Matched Iupac: … acid ... 2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Arbaclofen, or STX209, is the R-enantiomer of baclofen. It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo controlled trials. It has also been investigated as...
Investigational
Matched Synonyms: … (R)-4-amino-3-(4-chlorophenyl)butan­oic acid
Matched Iupac: … (3R)-4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated ... as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo ... It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord …
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … AZATHIOPRIN ACIS 50MG …
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Neomycin Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives …
Matched Products: … DEXAMETHASON ACIS 4MG ... DEXAMETHASON ACIS 8MG ... DEXAMETHASON ACIS 40MG …
Experimental
Matched Synonyms: … Methylphosphonic acid bis(1-methylethyl)ester …
Experimental
Matched Synonyms: … 3'-Uridylic acid
Matched Iupac: … acid ... ,3S,4R,5R)-4-hydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Synonyms: … Nitric acid, gallium salt, anhydrate …
Matched Description: … [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. ... cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and
Matched Categories: … Calcium-Regulating Hormones and Agents …
Lithium has been used to treat manic episodes since the 19th century . Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Approved
Matched Synonyms: … Carbonic acid, dilithium salt …
Matched Description: … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse …
Matched Categories: … Acids ... Carbonic Acid ... Acids, Noncarboxylic …
Experimental
Matched Synonyms: … Hexadecanoic acid, hexadecyl ester …
Matched Categories: … Fatty Acids ... Palmitic Acids
Experimental
Matched Synonyms: … 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide …
Experimental
Matched Name: … 3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol …
Matched Iupac: … 3-[4-(but-2-yn-1-yloxy)benzenesulfonyl]propane-1-thiol …
Experimental
Matched Synonyms: … Vanillic acid, methyl ester ... 4-hydroxy-3-methoxybenzoic acid methyl ester …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid ... 5-[[trans-4-[(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Experimental
Matched Synonyms: … 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
Matched Description: … inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and ... Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl
Experimental
Investigational
Matched Synonyms: … Hexahydro-2-imino-1h-thieno(3,4-d)imidazole-4-pentanoic acid
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … 3-(4-diethylamino-2-hydroxy-phenyl)-2-methyl-propionic acid
Matched Name: … alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid
Matched Iupac: … (2E)-3-[4-(diethylamino)-2-hydroxyphenyl]-2-methylprop-2-enoic acid
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Synonyms: … meso-Tetra-O-methylnordihydroguaiaretic acid
Matched Description: … Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors. …
Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium oxide.
Experimental
Matched Synonyms: … Aspartic acid, magnesium salt …
Matched Description: … magnesium citrate, magnesium carbonate and magnesium oxide. ... It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as ... Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... indometacin and antiinfectives ... Topical Products for Joint and Muscular Pain …
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Synonyms: … (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ... all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid
Matched Iupac: … (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Matched Categories: … Skin and Mucous Membrane Agents …
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and ... Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Investigational
Matched Synonyms: … 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Experimental
Nutraceutical
Matched Synonyms: … Palmitic acid monoethanolamide ... Monoethanolamine palmitic acid amide …
Matched Description: … In Italy and Spain (300 mg and 600 mg tablets). ... Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes …
Matched Categories: … Cannabinoids and similars ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Fatty Acids
Displaying drugs 2001 - 2025 of 3013 in total