Displaying drugs 2101 - 2125 of 3079 in total
2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Experimental
Matched Name: … 2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … N-[(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl](tert-butoxy)carboximidic acid …
Matched Iupac: … N-[(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl](tert-butoxy)carboximidic acid …
Phenylalanine
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (S)-2-Amino-3-phenylpropionic acid ... (S)-alpha-Amino-beta-phenylpropionic acid …
Matched Iupac: … (2S)-2-amino-3-phenylpropanoic acid …
Matched Description: … ] (norepinephrine), and [thyroxine]. ... Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn II with Electrolytes in Dextrose with Calcium …
Matched Salts name: … Phenylalanine sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
Matched Iupac: … (2S)-2-amino-3-phenylpropanoic acid …
Matched Description: … ] (norepinephrine), and [thyroxine]. ... Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn II with Electrolytes in Dextrose with Calcium …
Matched Salts name: … Phenylalanine sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
N-Acetylalanine
Experimental
Matched Synonyms: … 2-acetamidopropionic acid ... (S)-2-(acetylamino)propanoic acid …
Matched Iupac: … (2S)-2-acetamidopropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-acetamidopropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Abequolixron
Investigational
Matched Synonyms: … ((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2- diphenylethyl)amino)butoxy)phenyl)acetic acid ... -((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid ... -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Zanamivir
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid ... 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Sialic Acids ... Hydroxy Acids ... Carboxylic Acids …
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Sialic Acids ... Hydroxy Acids ... Carboxylic Acids …
(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
Experimental
Matched Synonyms: … (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
S-Ethylisothiourea
S-Ethylisothiourea is a nitric oxide synthase inhibitor.
Experimental
Matched Synonyms: … CARBAMIMIDOTHIOIC ACID, ETHYL ESTER …
Matched Salts name: … S-ethylisothiouronium diethyl phosphate …
Matched Categories: … Hypnotics and Sedatives ... Sulfur Compounds …
Matched Salts name: … S-ethylisothiouronium diethyl phosphate …
Matched Categories: … Hypnotics and Sedatives ... Sulfur Compounds …
Cilomilast
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
Matched Synonyms: … cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and ... It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and ... It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Lithium citrate
Approved
Matched Synonyms: … Citric acid, trilithium salt …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
VMD-928
Investigational
Matched Synonyms: … 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID ... 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid ... BENZOIC ACID, 4-((4-AMINO-3-(4-CYCLOHEXYL-1-PIPERAZINYL)-9,10-DIHYDRO-9,10-DIOXO-1-ANTHRACENYL)AMINO) …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid …
Zomepirac
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Synonyms: … 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Salts name: … Zomepirac sodium ... Zomepirac sodium anhydrous …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Salts name: … Zomepirac sodium ... Zomepirac sodium anhydrous …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Glucarpidase
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Pteroylmonoglutamic acid hydrolase G2 …
Matched Description: … [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin ... It is a 390-amino acid homodimer protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin ... It is a 390-amino acid homodimer protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Indium In-111 pentetate
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Synonyms: … Indium (111In) pentetic acid …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …
Matched Iupac: … [(2R,3R,4R,5R,6S)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …
Matched Iupac: … [(2R,3R,4R,5R,6S)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …
Oleoyl-estrone
Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance. Body protein loss is an...
Investigational
Matched Synonyms: … Estrone oleic acid ester …
Matched Description: … This hormone occurs naturally and is found circulating in various animal species and humans. ... Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show ... Oleoyl-estrone (OE) is a fatty acid ester of estrone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Description: … This hormone occurs naturally and is found circulating in various animal species and humans. ... Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show ... Oleoyl-estrone (OE) is a fatty acid ester of estrone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
rhGAD65
rhGAD65 (recombinant human glutamic acid decarboxylase) is a vaccine being developed to treat insulin dependent type 1 diabetes.
Investigational
Matched Synonyms: … Recombinant human glutamic acid decarboxylase …
Matched Description: … rhGAD65 (recombinant human glutamic acid decarboxylase) is a vaccine being developed to treat insulin …
Matched Description: … rhGAD65 (recombinant human glutamic acid decarboxylase) is a vaccine being developed to treat insulin …
Bicyclol
Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).
Investigational
Matched Synonyms: … 4,4'-bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester …
Vonafexor
Investigational
Matched Synonyms: … 2-benzofurancarboxylic acid, 4-chloro-5-(4-((2,6-dichlorophenyl)sulfonyl)-1-piperazinyl)- …
Adapalene
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Synonyms: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester ... (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[5-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
Matched Iupac: … methyl N-[5-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
PXL-770 free acid anhydrous
Investigational
Matched Synonyms: … PXL770 free acid anhydrous ... PXL 770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Displaying drugs 2101 - 2125 of 3079 in total