Displaying drugs 2101 - 2125 of 2865 in total
Gemfibrozil
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Eluxadoline
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Guaiacol
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
DPDPE
A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Experimental
Matched Synonyms: … L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide …
Matched Iupac: … -7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid …
Matched Description: … peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … -7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid …
Matched Description: … peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … 6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide …
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances ... Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... and other systemic adverse effects. …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances ... Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... and other systemic adverse effects. …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Iloprost
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid ... )-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acid ... PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately ... [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately ... [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Udonitrectag
Investigational
Matched Synonyms: … (1s,4r,5r,7s)-3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid ... 3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid, (1s,4r,5r,7s)- ... 6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylic acid, 2-oxo-3,4-bis(phenylmethyl)-, (1s,4r,5r,7s)- …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
Matched Salts name: … Udonitrectag L-lysine …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
Matched Salts name: … Udonitrectag L-lysine …
3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid …
5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid …
2-Amino-3-Oxo-4-Sulfo-Butyric Acid
Experimental
Matched Name: … 2-Amino-3-Oxo-4-Sulfo-Butyric Acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid …
3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid
Experimental
Matched Name: … 3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid …
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid …
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid …
2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Experimental
Matched Name: … 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid …
11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID
Experimental
Matched Name: … 11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID …
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid …
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid …
(2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Experimental
Matched Name: … METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER …
Matched Iupac: … methyl(4-nitrophenoxy)phosphinic acid …
Matched Iupac: … methyl(4-nitrophenoxy)phosphinic acid …
2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID
Experimental
Matched Name: … 2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Ezabenlimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 …
Zimberelimab
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mimosine
Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
Experimental
Matched Synonyms: … Leucenine …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid …
Matched Description: … Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alanine ... Amino Acids …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid …
Matched Description: … Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alanine ... Amino Acids …
N-2-Thiophen-2-Yl-Acetamide Boronic Acid
Experimental
Matched Name: … N-2-Thiophen-2-Yl-Acetamide Boronic Acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Hexanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Vitamin B6 Complexed with 2-Amino-Pentanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Pentanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
Displaying drugs 2101 - 2125 of 2865 in total