Displaying drugs 2176 - 2200 of 6806 in total
CEP-9722
CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
Investigational
Matched Iupac: … 14-methoxy-9-[(4-methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.0^{2,6}.0^{7,11}.0^{13,18}] …
ASN90
Investigational
SRP-9005
SRP-9005 is a rAAVrh74 vector containing a codon-optimized human SGCG transgene. Developed by the Kurt+Peter Foundation and Sarepta Therapeutics, it is being investigated for the treatment of Limb-girdle muscular dystrophy (LGMD) type 2C/R5.
Investigational
o-Cymen-5-ol
Experimental
Matched Synonyms: … o-Cymen-5-ol ... 4-Isopropyl-m-cresol ... 4-Isopropyl-3-methylphenol …
Matched Name: … o-Cymen-5-ol …
Matched Iupac: … 3-methyl-4-(propan-2-yl)phenol …
Matched Name: … o-Cymen-5-ol …
Matched Iupac: … 3-methyl-4-(propan-2-yl)phenol …
VLX-1570
VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in Myeloma Patients).
Investigational
Matched Synonyms: … (3E,5E)-3,5-Bis[(4-Fluoro-3-Nitrophenyl)Methylidene]-1-(Prop-2-Enoyl)Azepan-4-0Ne …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
Experimental
Matched Name: … 5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE …
Matched Iupac: … 5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]-1,3-diazinane-2,4,6-trione …
Matched Iupac: … 5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]-1,3-diazinane-2,4,6-trione …
Obeldesivir
Investigational
Matched Synonyms: … ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl ... 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D -altrononitrile 6-(2-methylpropanoate) ... D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(2-methylpropanoate) …
2''-O-[N-(3-(aminopropyl)2-aminoethyl]paromomycin
Experimental
Matched Iupac: … (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3R,4R,5S)-4-{2-[(3-aminopropyl)amino]ethoxy}-5-{[(1R ... ,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}- …
Kojic acid
Experimental
Matched Synonyms: … 5-hydroxy-2-(hydroxymethyl)-4-pyrone ... 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one …
Matched Iupac: … 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one …
Matched Iupac: … 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one …
Denifanstat
Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.
Investigational
Matched Synonyms: … Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)- …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
ANC-501
ANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Investigational
Matched Synonyms: … 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4- ... triazole-4-acetamide …
5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
Experimental
Matched Name: … 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
Bioymifi
Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent.[A257048,A257053]
Investigational
Matched Synonyms: … 5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione ... 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3- …
Matched Iupac: … 6-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-hydroxy-1H-isoindol …
Matched Description: … Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through …
Matched Iupac: … 6-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-hydroxy-1H-isoindol …
Matched Description: … Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through …
EGT-301
EGT-301 is a gene therapy being investigated for Hunter Syndrome. It consists of an adeno-associated viral vector serotype 9 (AAV9) containing the human Iduronate-2-sulfatase (I2S) transgene designed to restore I2S functional deficiency in patients with Hunter syndrome.
Investigational
Matched Description: … It consists of an adeno-associated viral vector serotype 9 (AAV9) containing the human Iduronate-2-sulfatase …
KX-2361
Investigational
Matched Synonyms: … 2-pyridineacetamide, n-((3-fluorophenyl)methyl)-5-(4-(4-morpholinyl)phenyl)- ... N-(3-fluorobenzyl)-2-(5-(4-morpholinophenyl) pyridin-2-yl) acetamide …
Matched Iupac: … N-[(3-fluorophenyl)methyl]-2-{5-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}acetamide …
Matched Iupac: … N-[(3-fluorophenyl)methyl]-2-{5-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}acetamide …
Tyrphostin B44
Experimental
Deuruxolitinib
Deuruxolitinib is under investigation in clinical trial NCT03898479 (Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata).
Investigational
Matched Synonyms: … -(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)- ... (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile …
Brevenal
Investigational
2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid
Experimental
Matched Synonyms: … (2R,4S,5R,6R)-5-Acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … (2R,4S,5R,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … (2R,4S,5R,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic …
Gaboxadol
Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of benzodiazepines. Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in...
Investigational
4-Methylimidazole
Experimental
Matched Synonyms: … 4(5)-methylimidazole ... 4-MEI …
Matched Name: … 4-Methylimidazole …
Matched Iupac: … 4-methyl-1H-imidazole …
Matched Name: … 4-Methylimidazole …
Matched Iupac: … 4-methyl-1H-imidazole …
Safusidenib
Investigational
Matched Synonyms: … (2E)-3-[1-[[5-(1-Fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]-3-methyl-1H-indol ... 2-Propenoic acid, 3-[1-[[5-(1-fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]- ... -4-yl]-2-propenoic acid …
C-(1-hydrogyl-beta-D-glucopyranosyl) formamide
Experimental
5-phospho-D-arabinohydroxamic acid
Experimental
Matched Synonyms: … (2R,3R,4S)-2,3,4-Trihydroxy-5-(hydroxyamino)-5-oxopentyl dihydrogen phosphate …
Matched Name: … 5-phospho-D-arabinohydroxamic acid …
Matched Iupac: … [(2R,3R,4S)-2,3,4-trihydroxy-4-(hydroxycarbamoyl)butoxy]phosphonic acid …
Matched Name: … 5-phospho-D-arabinohydroxamic acid …
Matched Iupac: … [(2R,3R,4S)-2,3,4-trihydroxy-4-(hydroxycarbamoyl)butoxy]phosphonic acid …
Fenvalerate
Investigational
Matched Synonyms: … methyl (R)-4-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-((4-((pyridin-3- ylmethyl)amino ... -cyano-3-phenoxybenzyl (2rs)-2-(4-chlorophenyl)-3-methylbutyrate ... -cyano-3-phenoxybenzyl (rs)-2-(4-chloro-phenyl)-3-methylbutyrate …
Matched Iupac: … cyano(3-phenoxyphenyl)methyl 2-(4-chlorophenyl)-3-methylbutanoate …
Matched Iupac: … cyano(3-phenoxyphenyl)methyl 2-(4-chlorophenyl)-3-methylbutanoate …
Displaying drugs 2176 - 2200 of 6806 in total