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Displaying drugs 2251 - 2275 of 6882 in total
Experimental
Matched Name: … (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE …
Matched Iupac: … (5R)-5-[(1E)-buta-1,3-dien-1-yl]-4-hydroxy-3,5-dimethyl-2,5-dihydrothiophen-2-one …
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. Additionally, genistein has antihelmintic activity. It has been...
Investigational
Matched Synonyms: … 5,7-dihydroxy-3-(4-hydroxyphenyl)-chromen-4-one ... 4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)- ... 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one …
Matched Iupac: … 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one …
Investigational
Matched Synonyms: … -d-ribofuranosyl)-5'-c-((2s)-5-(((4-butylphenyl)amino)carbonyl)-2,3,4,7-tetrahydro-1,4-dimethyl-3-oxo ... -2-yl]methyl}-N-(4-butylphenyl)-4,7-dimethyl-6-oxocyclohept-1-ene-1-carboxamide ... Uridine, 5'-o-(5-amino-5-deoxy-.beta. …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo ... (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... -2,3,4,7-tetrahydro-1H-1,4-diazepine-5-carboxamide …
JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug...
Investigational
INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.
Investigational
Matched Iupac: … 5-{4-[(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl] ... -4-methylpiperidine-1-carbonyl}-4,6-dimethylpyrimidine …
Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … (+)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methanesulfinyl)ethoxy)phenyl)piperazin-1- yl)ethyl)-8-(furan ... Thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, 5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl ... Thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, 5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methylsulfinyl …
Investigational
Matched Synonyms: … .,2.alpha.,4.beta.,5.alpha ... 1-((1s,2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-2,4(1h,3h)-pyrimidinedione ... 2,4(1h,3h)-pyrimidinedione, 1-((1s,2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl …
Matched Iupac: … 1-[(1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine …
Experimental
Matched Name: … 5-[4-(2-Hydroxyethyl)-1-piperidinyl]-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … (5R)-2-hydroxy-5-[4-(2-hydroxyethyl)piperidin-1-yl]-5-phenyl-1,4,5,6-tetrahydropyrimidine-4,6-dione …
Investigational
Matched Synonyms: … )-5-(2-(4-morpholinyl)ethyl)- ... 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl ... 4h-thieno(2,3-c)pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl …
Experimental
Matched Iupac: … (1S,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Experimental
Matched Synonyms: … 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid ... ACETIC ACID, (4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL)- …
Matched Iupac: … 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid …
Experimental
Matched Name: … 5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione …
Matched Iupac: … 5-methyl-5-(4-phenoxyphenyl)-1,3-diazinane-2,4,6-trione …
A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Experimental
Matched Synonyms: … 5'-CMP …
Matched Name: … Cytidine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase. …
Matched Salts name: … Cytidine 5'-Monophosphate Disodium Salt …
Investigational
Matched Synonyms: … ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl ... 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D -altrononitrile 6-(2-methylpropanoate) ... D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(2-methylpropanoate) …
Experimental
Matched Name: … 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL …
Matched Iupac: … 4-[(1S,2R,5S)-4,4,8-trimethyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol …
Experimental
Matched Iupac: … (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3R,4R,5S)-4-{2-[(3-aminopropyl)amino]ethoxy}-5-{[(1R ... ,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}- …
C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV).
Investigational
ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC)....
Investigational
Matched Description: … ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B …
Investigational
Experimental
Matched Synonyms: … o-Cymen-5-ol ... 4-Isopropyl-m-cresol ... 4-Isopropyl-3-methylphenol …
Matched Name: … o-Cymen-5-ol …
Matched Iupac: … 3-methyl-4-(propan-2-yl)phenol …
VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in Myeloma Patients).
Investigational
Matched Synonyms: … (3E,5E)-3,5-Bis[(4-Fluoro-3-Nitrophenyl)Methylidene]-1-(Prop-2-Enoyl)Azepan-4-0Ne …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Experimental
Investigational
Matched Synonyms: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Experimental
Matched Name: … (2R,4S,5R,6R)-5-Acetamido-4-amino-6-(diethylcarbamoyl)oxane-2-carboxylic acid …
Matched Iupac: … (2R,4S,5R,6R)-4-amino-6-(diethylcarbamoyl)-5-acetamidooxane-2-carboxylic acid …
Experimental
Matched Synonyms: … 5-hydroxy-2-(hydroxymethyl)-4-pyrone ... 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one …
Matched Iupac: … 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one …
Displaying drugs 2251 - 2275 of 6882 in total