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Displaying drugs 2251 - 2275 of 3566 in total
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ... [(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … -7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Salts name: … Cefalexin sodium ... Cefalexin monohydrate
Matched Categories: … Sulfur Compounds …
Matched Products: … CEFALEXIN MONOHYDRATE ... เซฟฟ่า 125 ... วาทาเซฟ 125
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Synonyms: … Acetic acid 4-(2-hydroxy-3-isopropylamino-propoxy)-2,3,6-trimethyl-phenyl ester …
Matched Description: … A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. ... It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent. …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... metipranolol and thiazides, combinations …
Experimental
Matched Synonyms: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Experimental
Matched Synonyms: … (+/-)-alpha-amino-4-hydroxybenzeneacetic acid
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Matched Description: … , thereby reducing serum uric acid levels. ... a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints ... granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and
Matched Categories: … Preparations Inhibiting Uric Acid Production ... Sulfur Compounds …
Matched Products: … ADENURIC 120 MG ... GOUTEX 120 MG ... FEBUDAY®120 MG …
Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Synonyms: … Technetium-99m-Diisopropyliminodiacetic Acid
Matched Iupac: … 2-[({[2,6-bis(propan-2-yl)phenyl]carbamoyl}methyl)(carboxymethyl)amino]acetic acid (99Tc)technetium …
Matched Description: … and its hepatic uptake is not as highly dependent on serum bilirubin levels (a competitive inhibitor ... Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with ... the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Amino Acids ... Amino Acids, Cyclic …
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Synonyms: … Technetium Tc 99m dimercaptosuccinic acid
Matched Iupac: … (2R,3S)-2,3-disulfanylbutanedioic acid (99Tc)technetium …
Matched Description: … (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular ... Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid ... Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography …
Matched Categories: … Indicators and Reagents ... Sulfur Compounds ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis.
Vet approved
Matched Synonyms: … 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid
Matched Description: … Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and ... as hip dysplasia and arthritis. ... It is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such …
Investigational
Matched Synonyms: … Blood group b trisaccharide …
Matched Categories: … ABO Blood-Group System …
Experimental
Matched Synonyms: … D-Fructose 6-phosphoric acid
Matched Iupac: … {[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acid
An obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Experimental
Matched Synonyms: … 2-Methylbenzoic acid anilide …
Matched Description: … An obsolete fungicide used to control various pathogens on cereals and seed potatoes. …
Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Investigational
Matched Synonyms: … 3'-thymidylic acid, monobutyl ester, 5'-(butyl hydrogen phosphate) …
Matched Iupac: … phosphoryl]oxy}-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid
Investigational
Matched Synonyms: … 1h-pyrazole-4-carboxylic acid, 1-(3-cyano-1-(1-methylethyl)-1h-indol-5-yl)- …
Investigational
Matched Synonyms: … H-arg-leu-phe-phe-tyr-arg-lys-ser-val-oh ... L-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl-l-valine ... L-valine, l-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …
Experimental
Matched Synonyms: … (E)-4-(3-Oxo-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
Matched Iupac: … 4-[(1E)-3-oxo-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid
Experimental
Matched Synonyms: … Deoxyuridylic acid
Matched Iupac: … {[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Description: … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for ... The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and
Matched Products: … Fypalan 12 mg-Filmtabletten ... FYCOMPA FILM-COATED TABLET 12MG ... LAPAROL® 12MG TABLETA RECUBIERTA …
Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 ... γ1-chain), disulfide with human-Mus musculus monoclonal JNJ-63733657 κ-chain, dimer …
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Matched Description: … broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … Pegylated human c-peptide …
Matched Name: … Pegylated synthetic human c-peptide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Blood Glucose Lowering Agents …
Investigational
Matched Synonyms: … Ciliary neurotrophic factor, recombinant human
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Investigational
Matched Synonyms: … RECOMBINANT HUMAN PLACENTAL GROWTH FACTOR …
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Displaying drugs 2251 - 2275 of 3566 in total