Displaying drugs 2251 - 2275 of 3628 in total
SR-9009
SR-9009 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues .
Experimental
Matched Synonyms: … 1-Pyrrolidinecarboxylic acid, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-, …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Benzylparaben
Benzylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … p-Hydroxybenzoic acid benzyl ester …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
rAAV1-CB-hAAT
rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.
Investigational
Matched Synonyms: … recombinant adeno-associated virus alpha 1-antitrypsin vector …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … 2-(β-methylaminoethyl)pyridine ... 2-[2-(methylamino)ethyl]pyridine …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Non-selective Beta-adrenergic Agonists …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Non-selective Beta-adrenergic Agonists …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …
Candoxatril
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with …
Matched Categories: … beta-Lactams ... Thiazines …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with …
Matched Categories: … beta-Lactams ... Thiazines …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Aspacytarabine
Investigational
Matched Synonyms: … L-asparagine, n-(1-.beta.-d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)- ... N4-(1-.beta.-d-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)-l-asparagine …
Matched Iupac: … 5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}carbamoyl)propanoic acid …
Matched Iupac: … 5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}carbamoyl)propanoic acid …
(2R)-2-{(1R)-2-oxo-1-[(2-thienylacetyl)amino]ethyl}-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid
Experimental
Matched Name: … (2R)-2-{(1R)-2-oxo-1-[(2-thienylacetyl)amino]ethyl}-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid …
Matched Iupac: … (2R)-2-[(1R)-2-oxo-1-[2-(thiophen-2-yl)acetamido]ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid …
Matched Iupac: … (2R)-2-[(1R)-2-oxo-1-[2-(thiophen-2-yl)acetamido]ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid …
Cathinone
Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat). Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that its structure is a ketone. Other amphetamines to share...
Illicit
Matched Synonyms: … alpha-Aminopropiophenone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Topotecan
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …
Trimethoprim
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid ... (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Salts name: … Trimethoprim hydrochloride …
Matched Categories: … Folic Acid Antagonists ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Medications that reduce magnesium levels ... Trimethoprim and Derivatives ... Sulfonamides and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Salts name: … Trimethoprim hydrochloride …
Matched Categories: … Folic Acid Antagonists ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Medications that reduce magnesium levels ... Trimethoprim and Derivatives ... Sulfonamides and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …
Meperidine
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …
Naltrexone
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …
Nalmefene
Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …
(4e)-4-Aminohex-4-Enoic Acid
Experimental
Matched Name: … (4e)-4-Aminohex-4-Enoic Acid …
Matched Iupac: … (4E)-4-aminohex-4-enoic acid …
Matched Iupac: … (4E)-4-aminohex-4-enoic acid …
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
4-(Acetylamino)-3-Amino Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-Amino Benzoic Acid …
Matched Iupac: … 3-amino-4-acetamidobenzoic acid …
Matched Iupac: … 3-amino-4-acetamidobenzoic acid …
5-Mercapto-2-Nitro-Benzoic Acid
Experimental
Matched Name: … 5-Mercapto-2-Nitro-Benzoic Acid …
Matched Iupac: … 2-nitro-5-sulfanylbenzoic acid …
Matched Iupac: … 2-nitro-5-sulfanylbenzoic acid …
2-Anhydro-3-Fluoro-Quinic Acid
Experimental
Matched Name: … 2-Anhydro-3-Fluoro-Quinic Acid …
Matched Iupac: … (1R,4S,5R)-3-fluoro-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid …
Matched Iupac: … (1R,4S,5R)-3-fluoro-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid …
3-Fluoro-2-(Phosphonooxy)Propanoic Acid
Experimental
Matched Name: … 3-Fluoro-2-(Phosphonooxy)Propanoic Acid …
Matched Iupac: … (2R)-3-fluoro-2-(phosphonooxy)propanoic acid …
Matched Iupac: … (2R)-3-fluoro-2-(phosphonooxy)propanoic acid …
4-Methyl-Pyrroline-5-Carboxylic Acid
Experimental
Matched Name: … 4-Methyl-Pyrroline-5-Carboxylic Acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid
Experimental
Matched Name: … 3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid …
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid …
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid …
Displaying drugs 2251 - 2275 of 3628 in total