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Displaying drugs 2326 - 2350 of 2435 in total
3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
Experimental
Matched Categories: … Triose-Phosphate Isomerase, antagonists & inhibitors …
Sar9, Met (O2)11-Substance P
Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
Investigational
Matched Categories: … Receptors, Neurokinin-3, antagonists & inhibitors …
Tanzisertib
Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
Investigational
Matched Categories: … JNK Mitogen-Activated Protein Kinases, antagonists & inhibitors …
N,O-didansyl-L-tyrosine
Experimental
Matched Categories: … Thymidylate Synthase, antagonists & inhibitors …
Pegdinetanib
CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway. As a result, CT-322 blocks all known ligands for VEGFR-2.
Investigational
Matched Categories: … Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitors …
Regramostim
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Categories: … Cholinesterase Inhibitors …
Istaroxime
Investigational
Matched Categories: … Sodium-Potassium-Exchanging ATPase, antagonists & inhibitors …
Limaprost
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Investigational
Matched Categories: … Platelet Aggregation Inhibitors Excl. Heparin …
Firocoxib
Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use...
Experimental
Vet approved
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Masitinib
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Categories: … Protein Kinase Inhibitors …
ONO-8539
ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
Investigational
Matched Categories: … Receptors, Prostaglandin E, EP1 Subtype, antagonists & inhibitors …
Chelerythrine
A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Categories: … Protein Kinase C, antagonists & inhibitors …
Atamestane
Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent.
Investigational
Matched Categories: … Enzyme Inhibitors …
Surinabant
Surinabant has been investigated for the treatment of Smoking Cessation.
Investigational
Matched Categories: … Receptor, Cannabinoid, CB1, antagonists & inhibitors …
13-cis-12-(3'-Carboxyphenyl)retinoic acid
Experimental
Matched Categories: … Phospholipases A, antagonists & inhibitors …
Ellipticine
Ellipticine is a potent antineoplastic agent.
Investigational
Matched Categories: … Enzyme Inhibitors …
Y-27632
Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Experimental
Matched Categories: … Enzyme Inhibitors …
Umifenovir
Umifenovir is an indole-based, hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of influenza and other respiratory infections. It has been in use in Russia for approximately 25 years and in China since 2006. Its invention is credited to a collaboration between Russian scientists from several research...
Investigational
Matched Categories: … UGT1A9 Inhibitors ... UGT2B7 Inhibitors …
Ibipinabant
Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
Investigational
Matched Categories: … Receptor, Cannabinoid, CB1, antagonists & inhibitors …
Omipalisib
Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Coagulation factor XIa
Coagulation factor XIa is under investigation in clinical trial NCT01701947 (HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency).
Investigational
Matched Categories: … Factor XIa, antagonists & inhibitors …
Oglufanide
Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before being acquired by...
Investigational
Matched Categories: … Growth Inhibitors …
Displaying drugs 2326 - 2350 of 2435 in total