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Displaying drugs 2401 - 2425 of 3051 in total
Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs are being developed by Sarawak Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared...
Investigational
Matched Iupac: … (10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-6,10,11,12-tetrahydro-2H-1,5,9-trioxatriphenylen …
Investigational
Investigational
Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others.
Investigational
Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
Investigational
Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Experimental
Nutraceutical
Investigational
Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.
Investigational
Neovastat is a naturally occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of action that provide broad therapeutic potential for a number of diseases. It is currently in international Phase III trials for renal cell carcinoma and non-small-cell lung cancer.
Investigational
Heat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine.
Investigational
Matched Description: … Heat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine. …
Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks in Patients With Schizophrenia on Stable Antipsychotic Treatment.).
Investigational
Matched Description: … Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12
Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties. Lactoferrin, a protein found in breast milk is developed by Agennix. It increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation.
Investigational
Matched Categories: … Recombinant Proteins …
Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN.
Investigational
Matched Description: … Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN. …
VB4-845 is studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. VB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor...
Investigational
Matched Categories: … Recombinant Proteins …
Investigational
Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.[A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time.[A234215,...
Investigational
Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring lysines have been removed as compared to wild type human...
Investigational
Matched Description: … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). ... multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human ... Specifically, the amino acid sequence of MAXY-G34 differs from that of human wild type G-CSF at residues …
Matched Categories: … Recombinant Proteins …
1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Experimental
Matched Description: … 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. …
Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.
Experimental
CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).
Investigational
Matched Description: … CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP). …
Investigational
tgAAG-76 consists of a recombinant adeno-associated virus (serotype 2) (rAAV2) gene transfer agent expressing RPE65.
Investigational
Matched Description: … tgAAG-76 consists of a recombinant adeno-associated virus (serotype 2) (rAAV2) gene transfer agent expressing …
Displaying drugs 2401 - 2425 of 3051 in total