Displaying drugs 2451 - 2475 of 3646 in total
LM-030
Investigational
Matched Synonyms: … (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL ... -.ALPHA.-((1S)-1-METHYLPROPYL)-2-OXO-1-PIPERIDINEACETYL-N-METHYL-L-TYROSYL-, (6->2)-LACTONE ... L-ISOLEUCINE, N2-(2-METHYL-1-OXOPROPYL)-L-GLUTAMINYL-L-THREONYL-L-LEUCYL-(.ALPHA.S,3S,6R)-3-AMINO-6-HYDROXY …
2-Fluoro-2-Deoxy-Beta-D-Galactopyranosyl-Beta-D-Glucopyranose
Experimental
Matched Name: … 2-Fluoro-2-Deoxy-Beta-D-Galactopyranosyl-Beta-D-Glucopyranose …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Salts name: … Etoricoxib hydrochloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB BETA 30MG ... ETORICOXIB BETA 60MG ... ETORICOXIB BETA 90MG …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Salts name: … Etoricoxib hydrochloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB BETA 30MG ... ETORICOXIB BETA 60MG ... ETORICOXIB BETA 90MG …
Auranofin
Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Synonyms: … (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate ... 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold …
Matched Iupac: … ,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-lambda5-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate …
Matched Description: … Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …
Matched Iupac: … ,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-lambda5-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate …
Matched Description: … Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …
4-nitrophenyl-beta-D-galactoside
Experimental
Matched Synonyms: … p-Nitrophenyl-beta-D-galactoside ... 4-Nitrophenyl-beta-D-galactopyranoside ... p-Nitrophenyl beta-D-galactopyranoside …
Matched Name: … 4-nitrophenyl-beta-D-galactoside …
Matched Categories: … Indicators and Reagents …
Matched Name: … 4-nitrophenyl-beta-D-galactoside …
Matched Categories: … Indicators and Reagents …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Synonyms: … methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(3,4-d)pyrimidine-5-carboxylic acid ... Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl …
Matched Iupac: … methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4-d]pyrimidine-5-carboxylic acid …
Matched Description: … , and reproductive dysfunction. ... It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis ... [A253642,A253647] It is similar to other GnRH receptor antagonists like [cetrorelix], [relugolix], and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins …
Matched Iupac: … methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4-d]pyrimidine-5-carboxylic acid …
Matched Description: … , and reproductive dysfunction. ... It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis ... [A253642,A253647] It is similar to other GnRH receptor antagonists like [cetrorelix], [relugolix], and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins …
Olmesartan
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid ... methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid …
Matched Iupac: … )-2-propyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid …
Matched Description: … and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [valsartan], and …
Matched Mixtures name: … OLMESART AMLO BETA 20/5MG ... OLMESART AMLO BETA 20/5MG ... OLMESART AMLO BETA 20/5MG …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine …
Matched Iupac: … )-2-propyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid …
Matched Description: … and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [valsartan], and …
Matched Mixtures name: … OLMESART AMLO BETA 20/5MG ... OLMESART AMLO BETA 20/5MG ... OLMESART AMLO BETA 20/5MG …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine …
Nafcillin
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Synonyms: … 6-(2-ethoxy-1-naphthamido)penicillanic acid ... )-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … )-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … beta-Lactams ... Beta-Lactam Antibacterials ... Beta-Lactamase Resistant Penicillins …
Matched Iupac: … )-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … beta-Lactams ... Beta-Lactam Antibacterials ... Beta-Lactamase Resistant Penicillins …
Cudetaxestat
Investigational
Matched Synonyms: … 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluorobenzoic acid ... Benzoic acid, 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluoro- …
Matched Iupac: … 3-{[2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]sulfanyl}-2-fluorobenzoic acid …
Matched Iupac: … 3-{[2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]sulfanyl}-2-fluorobenzoic acid …
Topiroxostat
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Xanthine oxidase inhibitors are classified into two groups; purine analogs such as...
Experimental
Matched Synonyms: … 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia ... Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the ... Xanthine oxidase inhibitors are classified into two groups; purine analogs such as [DB00437] and [DB05262 …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia ... Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the ... Xanthine oxidase inhibitors are classified into two groups; purine analogs such as [DB00437] and [DB05262 …
Oxaliplatin
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Description: … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. ... refractory to an initial fluorouracil and leucovorin combination. ... [A260396] The DACH moiety also prevents cross-resistance with cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXITEL …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXITEL …
Sotalol
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm …
Matched Salts name: … Sotalol hydrochloride …
Matched Categories: … sotalol and acetylsalicylic acid ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Medications that reduce magnesium levels ... sotalol and thiazides …
Matched Products: … Sotalol Hydrochloride ... Sotalol hydrochloride ... Sotalol Hydrochloride AF …
Matched Salts name: … Sotalol hydrochloride …
Matched Categories: … sotalol and acetylsalicylic acid ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Medications that reduce magnesium levels ... sotalol and thiazides …
Matched Products: … Sotalol Hydrochloride ... Sotalol hydrochloride ... Sotalol Hydrochloride AF …
Colesevelam
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Colesevelam Hydrochloride ... Colesevelam hydrochloride …
Matched Salts name: … Colesevelam hydrochloride …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Colesevelam Hydrochloride ... Colesevelam hydrochloride …
Aminoglutethimide
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … DL-Aminoglutethimide …
Matched Description: … Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
4-Thio-beta-D-glucopyranose
Experimental
Matched Synonyms: … 4-deoxy-4-Thio-beta-D-glucopyranose …
Matched Name: … 4-Thio-beta-D-glucopyranose …
Matched Name: … 4-Thio-beta-D-glucopyranose …
beta-D-Ribose-5-phosphate
Experimental
Matched Synonyms: … 5-O-phosphono-beta-D-ribofuranose …
Matched Name: … beta-D-Ribose-5-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Name: … beta-D-Ribose-5-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid …
beta-D-fructofuranose 1,6-bisphosphate
Experimental
Matched Synonyms: … beta-D-Fructose 1,6-bisphosphate …
Matched Name: … beta-D-fructofuranose 1,6-bisphosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4,5-trihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]methoxy}phosphonic acid …
Matched Name: … beta-D-fructofuranose 1,6-bisphosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-3,4,5-trihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]methoxy}phosphonic acid …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Salts name: … Idarubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Hydrochloride ... Idarubicin Hydrochloride Injection …
Matched Salts name: … Idarubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Hydrochloride ... Idarubicin Hydrochloride Injection …
octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside
Experimental
Matched Name: … octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside …
Trisaccharide A
Investigational
Matched Synonyms: … 3-o-(2-acetamido-2-deoxy-.alpha.-d-galactopyranosyl)-2-o-(.alpha.-l-fucopyranosyl)-d-galactose …
Metelimumab
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Human anti-transforming growth factor beta 1 monoclonal antibody ... Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta …
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors …
Matched Products: … Zinox Tablet 600mg ... LINEZOLID BETA 600MG FTA …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors …
Matched Products: … Zinox Tablet 600mg ... LINEZOLID BETA 600MG FTA …
Displaying drugs 2451 - 2475 of 3646 in total