Displaying all 19 drugs
Dolutegravir
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Synonyms: … Dolutegravir …
Matched Name: … Dolutegravir …
Matched Description: … Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. ... [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir ... dolutegravir ... dolutegravir and rilpivirine …
Matched Products: … Dolutegravir ... DOLUTEGRAVIR SODIUM ... DULET (Dolutegravir film-coated Tablets 50mg) …
Matched Name: … Dolutegravir …
Matched Description: … Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. ... [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir ... dolutegravir ... dolutegravir and rilpivirine …
Matched Products: … Dolutegravir ... DOLUTEGRAVIR SODIUM ... DULET (Dolutegravir film-coated Tablets 50mg) …
Abacavir
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … Abacavir …
Matched Name: … Abacavir …
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. ... Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV …
Matched Mixtures name: … Abacavir and Lamivudine ... Abacavir and Lamivudine ... Abacavir and lamivudine …
Matched Salts name: … Abacavir sulfate ... Abacavir hydrochloride ... Abacavir hydrochloride monohydrate …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and abacavir ... zidovudine, lamivudine and abacavir ... abacavir …
Matched Products: … ABALAM ABACAVIR SULFATE & LAMIVUDINE TABLETS 600/300 MG ... Abacavir ... Apo-abacavir …
Matched Name: … Abacavir …
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. ... Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV …
Matched Mixtures name: … Abacavir and Lamivudine ... Abacavir and Lamivudine ... Abacavir and lamivudine …
Matched Salts name: … Abacavir sulfate ... Abacavir hydrochloride ... Abacavir hydrochloride monohydrate …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and abacavir ... zidovudine, lamivudine and abacavir ... abacavir …
Matched Products: … ABALAM ABACAVIR SULFATE & LAMIVUDINE TABLETS 600/300 MG ... Abacavir ... Apo-abacavir …
Zidovudine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Mixtures name: … Abacavir, Lamivudine and Zidovudine ... Apo-abacavir-lamivudine-zidovudine ... Abacavir Sulfate, Lamivudine and Zidovudine …
Matched Categories: … zidovudine, lamivudine and abacavir ... zidovudine and lamivudine ... zidovudine, lamivudine and nevirapine …
Matched Categories: … zidovudine, lamivudine and abacavir ... zidovudine and lamivudine ... zidovudine, lamivudine and nevirapine …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... Apo-zidovudine-lamivudine-nevirapine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine …
Matched Categories: … stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine …
Adefovir dipivoxil
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Cabotegravir
Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193]
Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than [dolutegravir …
Entecavir
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine …
Doravirine
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Raltegravir
Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Categories: … lamivudine and raltegravir …
Lamivudine
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … Lamivudine …
Matched Name: … Lamivudine …
Matched Mixtures name: … Abacavir and Lamivudine ... Abacavir and Lamivudine ... Abacavir and lamivudine …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and abacavir ... lamivudine and dolutegravir ... zidovudine, lamivudine and abacavir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … Lamivudine ... LAMIVUDINE ... Apo-lamivudine …
Matched Name: … Lamivudine …
Matched Mixtures name: … Abacavir and Lamivudine ... Abacavir and Lamivudine ... Abacavir and lamivudine …
Matched Categories: … lamivudine, abacavir and dolutegravir ... lamivudine and abacavir ... lamivudine and dolutegravir ... zidovudine, lamivudine and abacavir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … Lamivudine ... LAMIVUDINE ... Apo-lamivudine …
Tenofovir disoproxil
Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … lamivudine, tenofovir disoproxil and dolutegravir ... lamivudine and tenofovir disoproxil ... lamivudine, tenofovir disoproxil and efavirenz ... lamivudine, tenofovir disoproxil and doravirine …
Matched Categories: … lamivudine, tenofovir disoproxil and dolutegravir ... lamivudine and tenofovir disoproxil ... lamivudine, tenofovir disoproxil and efavirenz ... lamivudine, tenofovir disoproxil and doravirine …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Description: … For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … lamivudine, tenofovir disoproxil and efavirenz …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … lamivudine, tenofovir disoproxil and efavirenz …
Stavudine
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Categories: … stavudine and lamivudine ... stavudine, lamivudine and nevirapine …
Rilpivirine
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [L1030] On November 21, 2017, Rilpivirine, in combination with [dolutegravir], was approved as part of …
Matched Categories: … dolutegravir and rilpivirine …
Matched Categories: … dolutegravir and rilpivirine …
Atazanavir
Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day)...
Approved
Investigational
Abacavir hydroxyacetate
Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.
Investigational
Matched Name: … Abacavir hydroxyacetate …
Oxymatrine
Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).
Investigational
Matched Description: … Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects). ... Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination …
Racivir
Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.
Investigational
Matched Description: … known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine …
Displaying all 19 drugs