Displaying drugs 1 - 25 of 14351 in total
Darbepoetin alfa
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Synonyms: … Darbepoetin alfa ... Darbepoetina alfa ... Darbepoetin alfa,recombinant …
Matched Name: … Darbepoetin alfa …
Matched Categories: … darbepoetin alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Name: … Darbepoetin alfa …
Matched Categories: … darbepoetin alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Aglucosidase alfa ... Alglucosidasa alfa ... Alglucosidase alfa …
Matched Name: … Alglucosidase alfa …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates …
Matched Categories: … alglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … (Alglucosidase alfa) 50mg Powder for Solution for Infusion …
Matched Name: … Alglucosidase alfa …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates …
Matched Categories: … alglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … (Alglucosidase alfa) 50mg Powder for Solution for Infusion …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Vestronidase alfa ... Vestronidase alfa-vjbk …
Matched Name: … Vestronidase alfa …
Matched Description: … In clinical trials, vestronidase alfa treatment demonstrated improvement and stabilization in motor symptoms ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … vestronidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Vestronidase alfa …
Matched Description: … In clinical trials, vestronidase alfa treatment demonstrated improvement and stabilization in motor symptoms ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … vestronidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Simoctocog alfa
Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Synonyms: … Simoctocog alfa …
Matched Name: … Simoctocog alfa …
Matched Description: … The harvested product is concentrated and purified by a series of chromatography steps. ... + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and ... potentially immunogenic glycosylation patterns found in non-human cell lines led to decreased immunogenicity and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Simoctocog alfa …
Matched Description: … The harvested product is concentrated and purified by a series of chromatography steps. ... + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and ... potentially immunogenic glycosylation patterns found in non-human cell lines led to decreased immunogenicity and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efgartigimod alfa
Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction. The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in...
Approved
Investigational
Matched Synonyms: … Efgartigimod alfa …
Matched Name: … Efgartigimod alfa …
Matched Description: … Efgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European ... [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was approved ... [L39509] By antagonizing this interaction, efgartigimod alfa prevents this recycling phase and thus decreases …
Matched Categories: … efgartigimod alfa ... Antineoplastic and Immunomodulating Agents …
Matched Name: … Efgartigimod alfa …
Matched Description: … Efgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European ... [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was approved ... [L39509] By antagonizing this interaction, efgartigimod alfa prevents this recycling phase and thus decreases …
Matched Categories: … efgartigimod alfa ... Antineoplastic and Immunomodulating Agents …
Andexanet alfa
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Synonyms: … Andexanet alfa …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … andexanet alfa ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … andexanet alfa ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Dibotermin alfa ... Dibotermina alfa …
Matched Name: … Dibotermin alfa …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... Dibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. ... Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Categories: … dibotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Name: … Dibotermin alfa …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... Dibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. ... Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Categories: … dibotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin alfa …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … PEG-IFN alfa-2A ... PEG-Interferon alfa-2A ... Peginterferon alfa-2a …
Matched Name: … Peginterferon alfa-2a …
Matched Description: … Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... When combined together, Peginterferon alfa-2a and [DB00811] have been shown to achieve a SVR between ... aggravation and development of endocrine and autoimmune disorders, retinopathies, cardiovascular and …
Matched Categories: … Alfa Interferons ... peginterferon alfa-2a ... Amino Acids, Peptides, and Proteins ... peginterferon alfa-2a, combinations ... Antineoplastic and Immunomodulating Agents …
Matched Name: … Peginterferon alfa-2a …
Matched Description: … Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... When combined together, Peginterferon alfa-2a and [DB00811] have been shown to achieve a SVR between ... aggravation and development of endocrine and autoimmune disorders, retinopathies, cardiovascular and …
Matched Categories: … Alfa Interferons ... peginterferon alfa-2a ... Amino Acids, Peptides, and Proteins ... peginterferon alfa-2a, combinations ... Antineoplastic and Immunomodulating Agents …
Antithrombin Alfa
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin Alfa …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Eptotermin alfa ... Eptotermina alfa …
Matched Name: … Eptotermin alfa …
Matched Description: … Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. ... It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … eptotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Name: … Eptotermin alfa …
Matched Description: … Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. ... It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … eptotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Eftrenonacog alfa …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Elosulfase alfa …
Matched Name: … Elosulfase alfa …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Categories: … elosulfase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Matched Name: … Elosulfase alfa …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Categories: … elosulfase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Ropeginterferon alfa-2b
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Ropeginterferon alfa-2b ... Ropeginterferon alfa-2b-njft …
Matched Name: … Ropeginterferon alfa-2b …
Matched Description: … [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models ... [A242010, A242015] Ropeginterferon alfa-2b was approved by the FDA on November 12, 2021, and is currently ... [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Alfa Interferons ... ropeginterferon alfa-2b …
Matched Name: … Ropeginterferon alfa-2b …
Matched Description: … [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models ... [A242010, A242015] Ropeginterferon alfa-2b was approved by the FDA on November 12, 2021, and is currently ... [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Alfa Interferons ... ropeginterferon alfa-2b …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Cerliponase alfa …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Inbakicept nogapendekin alfa fusion complex ... Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Name: … Nogapendekin alfa …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... product also containing [inbakicept], where a single inbakicept is complexed with two nogapendekin alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Nogapendekin alfa …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... product also containing [inbakicept], where a single inbakicept is complexed with two nogapendekin alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Name: … Efbemalenograstim alfa …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... GC-627-05 in the US and Europe respectively. …
Matched Categories: … efbemalenograstim alfa ... Antineoplastic and Immunomodulating Agents …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... GC-627-05 in the US and Europe respectively. …
Matched Categories: … efbemalenograstim alfa ... Antineoplastic and Immunomodulating Agents …
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Name: … Poractant alfa …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Epoetin alfa ... Epoetin alfa rDNA ... Epoetina alfa …
Matched Description: … States, followed by other alfa and beta formulations. ... Epoetin alfa biosimilar, such as Retacrit (epoetin alfa-epbx or epoetin zeta), has been formulated to ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EPOETIN ALFA ... Epoetin Alfa Hexal ... EPOETIN ALFA HEXAL 1000IE …
Matched Description: … States, followed by other alfa and beta formulations. ... Epoetin alfa biosimilar, such as Retacrit (epoetin alfa-epbx or epoetin zeta), has been formulated to ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EPOETIN ALFA ... Epoetin Alfa Hexal ... EPOETIN ALFA HEXAL 1000IE …
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Vorhyaluronidase alfa …
Matched Description: … Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Description: … Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Colestipol
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Eurotium amstelodami
Eurotium amstelodami allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, aspergillus amsterdami …
Tarlatamab
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and ... delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and ... delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Description: … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SOMATOSTATINA ALFA BIOTECH …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SOMATOSTATINA ALFA BIOTECH …
Displaying drugs 1 - 25 of 14351 in total