Phospholipase D1

BE0002181ProteinHumansPLD1

Function as phospholipase selective for phosphatidylcholine (PubMed:25936805, PubMed:8530346, PubMed:9582313). It is acted on by 6 drugs in DrugBank.

Gene name
PLD1
UniProtKB entry
Q13393Swiss-Prot
Cellular location
Cytoplasm, perinuclear region
Residues / weight
1,074 residues · 124,183 Da
Also known as
3.1.4.4 · Choline phosphatase 1 · hPLD1 · Phosphatidylcholine-hydrolyzing phospholipase D1 · PLD 1

Resolves to

Protein
UniProtQ13393UniProt namePLD1_HUMAN
Gene
HGNCHGNC:9067NCBI Gene5337GenBank1185463GeneCardsPLD1
Pharmacology
IUPHAR/GtoPdb1433KEGGhsa:5337
Structure
PDB6OHRPDB6U8Z
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Phospholipase D1, how selective are they, and which programs against it are still in active trials?

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