Protein S100-A11
Details
- Name
- Protein S100-A11
- Kind
- protein
- Synonyms
- Calgizzarin
- Metastatic lymph node gene 70 protein
- MLN 70
- MLN70
- Protein S100-C
- S100 calcium-binding protein A11
- S100C
- Gene Name
- S100A11
- UniProtKB Entry
- P31949Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0016894|Protein S100-A11 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT
- Number of residues
- 105
- Molecular Weight
- 11740.33
- Theoretical pI
- 7.26
- GO Classification
- Functionscadherin binding involved in cell-cell adhesionProcessesnegative regulation of cell population proliferation / positive regulation of smooth muscle cell migrationComponentsadherens junction / extracellular region / secretory granule lumen
- General Function
- Facilitates the differentiation and the cornification of keratinocytes
- Specific Function
- cadherin binding involved in cell-cell adhesion
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0016895|Protein S100-A11 (S100A11) ATGGCAAAAATCTCCAGCCCTACAGAGACTGAGCGGTGCATCGAGTCCCTGATTGCTGTC TTCCAGAAGTATGCTGGAAAGGATGGTTATAACTACACTCTCTCCAAGACAGAGTTCCTA AGCTTCATGAATACAGAACTAGCTGCCTTCACAAAGAACCAGAAGGACCCTGGTGTCCTT GACCGCATGATGAAGAAACTGGACACCAACAGTGATGGTCAGCTAGATTTCTCAGAATTT CTTAATCTGATTGGTGGCCTAGCTATGGCTTGCCATGACTCCTTCCTCAAGGCTGTCCCT TCCCAGAAGCGGACCTGA
- Chromosome Location
- 1
- Locus
- 1q21.3
- External Identifiers
Resource Link UniProtKB ID P31949 UniProtKB Entry Name S10AB_HUMAN GenBank Gene ID D38583 GeneCard ID S100A11 GenAtlas ID S100A11 HGNC ID HGNC:10488 PDB ID(s) 1V4Z, 1V50, 2LUC KEGG ID hsa:6282 NCBI Gene ID 6282 - General References
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- Tomasetto C, Regnier C, Moog-Lutz C, Mattei MG, Chenard MP, Lidereau R, Basset P, Rio MC: Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics. 1995 Aug 10;28(3):367-76. [Article]
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- Rasmussen HH, van Damme J, Puype M, Gesser B, Celis JE, Vandekerckhove J: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. Electrophoresis. 1992 Dec;13(12):960-9. [Article]
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Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Phosphonothreonine experimental unknown target Details