Carbonic anhydrase 6

BE0003628ProteinHumansCA6

Reversible hydration of carbon dioxide. It is acted on by 16 drugs in DrugBank.

Gene name
CA6
UniProtKB entry
P23280Swiss-Prot
Cellular location
Secreted
Residues / weight
308 residues · 35,367 Da
Also known as
4.2.1.1 · CA-VI · Carbonate dehydratase VI · Carbonic anhydrase VI · Salivary carbonic anhydrase

Resolves to

Protein
UniProtP23280UniProt nameCAH6_HUMAN
Gene
HGNCHGNC:1380NCBI Gene765GeneCardsCA6
Pharmacology
KEGGhsa:765
Structure
PDB3FE4
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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56+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carbonic anhydrase 6, how selective are they, and which programs against it are still in active trials?

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