ATP-binding cassette sub-family C member 10

BE0003651ProteinHumansABCC10

ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. It is acted on by 22 drugs in DrugBank.

Gene name
ABCC10
UniProtKB entry
Q5T3U5Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,492 residues · 161,627 Da
Also known as
7.6.2.2 · 7.6.2.3 · MRP7 · Multidrug resistance-associated protein 7 · SIMRP7

Resolves to

Protein
UniProtQ5T3U5UniProt nameMRP7_HUMAN
Gene
HGNCHGNC:52NCBI Gene89845GenBank21103955GeneCardsABCC10
Pharmacology
KEGGhsa:89845
Drugs

What you can answer from here — as of September 03, 2024

22DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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40+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP-binding cassette sub-family C member 10, how selective are they, and which programs against it are still in active trials?

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