Transcription factor RelB

BE0013795ProteinHumansRELB

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. It is acted on by 14 drugs in DrugBank.

Gene name
RELB
UniProtKB entry
Q01201Swiss-Prot
Cellular location
Nucleus
Residues / weight
579 residues · 62,134 Da
Also known as
I-Rel

Resolves to

Protein
UniProtQ01201UniProt nameRELB_HUMAN
Gene
HGNCHGNC:9956NCBI Gene5971GeneCardsRELB
Pharmacology
KEGGhsa:5971
Structure
PDB8G8R
Drugs

What you can answer from here — as of September 03, 2024

14DrugsApproved to experimental, with action, bond type and pharmacological action
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24GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transcription factor RelB, how selective are they, and which programs against it are still in active trials?

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