Mustard Compounds
DBCAT000681Pharmacologic class
Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. A DrugBank category of 26 drugs. 10 of them are approved.
- Also known as
- Compounds, Mustard
- Drugs
- Ambamustine
- Bendamustine
- Chlorambucil
- Cyclophosphamide
- Estramustine
- Estramustine phosphate
- Evofosfamide
- Glufosfamide
- Ifosfamide
- Mafosfamide
- Mannomustine
- Mechlorethamine
- Melphalan
- Melphalan flufenamide
- Metamelfalan
- Mitoclomine
- Mitozolomide
- Palifosfamide
- Perfosfamide
- PR-104
- Prednimustine
- Quinacrine mustard
- Spiromustine
- Tallimustine
- Trofosfamide
What you can answer from here — as of August 24, 2016
Which targets do Mustard Compounds share, and which companies have late-stage candidates in this class?
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