- Accession Number
Compounds consisting of the cycloheptene ring with one or two BENZENE rings fused to it.
Drug Drug Description Cyproheptadine A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. Loratadine A second generation antihistamine used to manage the symptoms of allergic rhinitis. Nortriptyline A tricyclic antidepressant used in the treatment of depression. Azatadine An H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion. Cyclobenzaprine A skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin. Desloratadine A second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria. Asenapine An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia. Amineptine For the treatment of depression. Elacridar For the treatment of solid tumors. OMS-103HP Investigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic). AMG-222 Investigated for use/treatment in diabetes mellitus type 2. Zosuquidar Investigated for use/treatment in leukemia (myeloid) and myelodysplastic syndrome. Demexiptiline Demexiptiline is marketed under the names Deparon or Tinoran. It is a tricyclic antidepressant which acts primarily as a norepinephrine reuptake inhibitor. Butriptyline Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline. Amitriptylinoxide A tricyclic antidepressant indicated in the treatment of depressive disorders. Protriptyline A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision. Rupatadine A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
- Drugs & Drug Targets