Glycosaminoglycans

Name
Glycosaminoglycans
Accession Number
DBCAT001272
Description

Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.

Drugs
DrugDrug Description
ArdeparinFor prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery.
HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
EnoxaparinA low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction.
SemuloparinInvestigated for use/treatment in thrombosis.
DanaparoidA heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT.
DalteparinA low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
TinzaparinA low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.
NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
Hyaluronic acidA glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
BemiparinAn ultra-low molecular weight heparin (ultra-LMWH) used to prevent thromboembolism following surgery and extracorporeal clotting during dialysis.
ReviparinBy the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of...
ParnaparinA low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
CertoparinA low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
Chondroitin sulfateChondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
Antithrombin III humanAn alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
Pentosan polysulfateA sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
SevuparinSevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin).
Dermatan sulfateA medication indicated to prevent deep vein thrombosis.
Drugs & Drug Targets
DrugTargetType
ArdeparinHeparin cofactor 2target
ArdeparinAntithrombin-IIItarget
HeparinAntithrombin-IIItarget
HeparinCoagulation factor Xtarget
HeparinP-selectintarget
HeparinHeparanaseenzyme
HeparinFibroblast growth factor receptor 4target
HeparinFibroblast growth factor 4target
HeparinFibroblast growth factor 19target
HeparinFibroblast growth factor receptor 1target
HeparinFibroblast growth factor 1target
HeparinFibroblast growth factor receptor 2target
HeparinFibroblast growth factor 2target
HeparinPlatelet factor 4target
HeparinHepatocyte growth factortarget
HeparinThyroxine-binding globulincarrier
EnoxaparinAntithrombin-IIItarget
EnoxaparinCoagulation factor Xtarget
EnoxaparinMyeloperoxidaseenzyme
EnoxaparinProthrombintarget
DanaparoidAntithrombin-IIItarget
DalteparinVascular endothelial growth factor Atarget
DalteparinTissue factor pathway inhibitortarget
DalteparinHeparanaseenzyme
DalteparinAntithrombin-IIItarget
DalteparinP-selectintarget
TinzaparinAntithrombin-IIItarget
TinzaparinA disintegrin and metalloproteinase with thrombospondin motifs 4enzyme
TinzaparinIntegrin alpha-4target
TinzaparinStromal cell-derived factor 1target
NadroparinProto-oncogene c-Fostarget
NadroparinMyc proto-oncogene proteintarget
NadroparinP-selectintarget
NadroparinAntithrombin-IIItarget
Hyaluronic acidCD44 antigentarget
Hyaluronic acidIntercellular adhesion molecule 1target
Hyaluronic acidHyaluronan mediated motility receptortarget
Hyaluronic acidNeurocan core proteintarget
Hyaluronic acidVersican core proteintarget
Hyaluronic acidComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
Hyaluronic acidHyaluronan and proteoglycan link protein 1target
Hyaluronic acidHyaluronan and proteoglycan link protein 3target
Hyaluronic acidHyaluronan-binding protein 2target
Hyaluronic acidLayilintarget
Hyaluronic acidStabilin-2target
Hyaluronic acidTumor necrosis factor-inducible gene 6 proteintarget
Hyaluronic acidInterphotoreceptor matrix proteoglycan 2target
Hyaluronic acidIntracellular hyaluronan-binding protein 4target
Hyaluronic acidHyaluronidase enzymesenzyme
Hyaluronic acidMultidrug resistance-associated protein 5transporter
Hyaluronic acidLymphatic vessel endothelial hyaluronic acid receptor 1target
BemiparinCoagulation factor Xtarget
BemiparinAntithrombin-IIItarget
BemiparinHeparin cofactor 2target
Chondroitin sulfateBrain-derived neurotrophic factortarget
Chondroitin sulfateGlial cell line-derived neurotrophic factortarget
Chondroitin sulfateVascular endothelial growth factor Atarget
Chondroitin sulfateC-C motif chemokine 2target
Chondroitin sulfateBeta-glucuronidaseenzyme
Chondroitin sulfateBeta-hexosaminidase subunit betaenzyme
Chondroitin sulfateN-acetylgalactosamine-6-sulfataseenzyme
Chondroitin sulfateIduronate 2-sulfataseenzyme
Chondroitin sulfateAlpha-L-iduronidaseenzyme
Chondroitin sulfateArylsulfatase Benzyme
Antithrombin III humanAntithrombin-IIItarget
Pentosan polysulfateFibroblast growth factor 1target
Pentosan polysulfateFibroblast growth factor 4target
Pentosan polysulfateFibroblast growth factor 2target