Accession Number

A class of natural cyclic peptide antibiotics produced by certain subspecies of STREPTOMYCES. They include two structurally unrelated components, STREPTOGRAMIN GROUP A and STREPTOGRAMIN GROUP B, which generally act synergistically to inhibit bacterial growth.

ATC Classification
DrugDrug Description
PristinamycinNot Annotated
Virginiamycin M1For the treatment of bacterial infections.
Virginiamycin S1One of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. It is used to treat infections...
VirginiamycinVirginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent...
QuinupristinAn antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections.
DalfopristinAn antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.
Drugs & Drug Targets
Virginiamycin M1Streptogramin A acetyltransferasetarget
Virginiamycin S160S ribosomal protein L37target
Quinupristin23S ribosomal RNAtarget
Quinupristin50S ribosomal protein L10target
Quinupristin50S ribosomal protein L22target
QuinupristinCytochrome P450 3A4enzyme
DalfopristinStreptogramin A acetyltransferasetarget
DalfopristinCytochrome P450 3A4enzyme