Cytochrome P-450 CYP3A7 Inhibitors

Accession Number

DBCAT003892

Description

Not Available

Drugs

Drug	Drug Description
Erythromycin	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.
Cimetidine	A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.
Fluvoxamine	A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
Prasterone	A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
Progesterone	A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
Cobicistat	A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Itraconazole	A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
Ketoconazole	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Ritonavir	An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Troleandomycin	For the treatment of bacterial infection.
Indinavir	A protease inhibitor used to treat HIV infection.
Saquinavir	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
Aprepitant	A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
Imatinib	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
Chloramphenicol	A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
Delavirdine	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
Gestodene	Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
Mibefradil	For the treatment of angina and high blood pressure.
Mifepristone	A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
Norfloxacin	A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
Seproxetine	Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an...
Voriconazole	A triazole compound used to treat fungal infections.
Phenelzine	A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
Troglitazone	For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
Idelalisib	An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
Oxymetholone	An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
Rucaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Letermovir	An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.
Diltiazem	A calcium channel blocker used to treat hypertension and to manage chronic stable angina.
Cannabidiol	An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Medical Cannabis	The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
Nabiximols	In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
Menadione	The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
Dronabinol	A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
Cannabinol	Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Encorafenib	A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
Atazanavir	An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.

Drugs & Drug Targets

Drug	Target	Type
Erythromycin	23S ribosomal RNA	target
Erythromycin	Cytochrome P450 3A4	enzyme
Erythromycin	Cytochrome P450 3A7	enzyme
Erythromycin	ATP-dependent translocase ABCB1	transporter
Erythromycin	Solute carrier organic anion transporter family member 1B1	transporter
Erythromycin	Motilin receptor	target
Erythromycin	Potassium voltage-gated channel subfamily H member 2	target
Erythromycin	Cytochrome P450 3A5	enzyme
Erythromycin	Solute carrier organic anion transporter family member 1B3	transporter
Erythromycin	Bile salt export pump	transporter
Erythromycin	ATP-binding cassette sub-family C member 2	transporter
Erythromycin	Solute carrier organic anion transporter family member 1A2	transporter
Cimetidine	Histamine H2 receptor	target
Cimetidine	Cytochrome P450 1A2	enzyme
Cimetidine	Cytochrome P450 2D6	enzyme
Cimetidine	Cytochrome P450 2C19	enzyme
Cimetidine	Cytochrome P450 3A4	enzyme
Cimetidine	Cytochrome P450 3A5	enzyme
Cimetidine	ATP-dependent translocase ABCB1	transporter
Cimetidine	Solute carrier family 22 member 2	transporter
Cimetidine	Solute carrier family 22 member 1	transporter
Cimetidine	Solute carrier family 22 member 3	transporter
Cimetidine	Organic cation/carnitine transporter 2	transporter
Cimetidine	Solute carrier family 22 member 6	transporter
Cimetidine	Organic anion transporter 3	transporter
Cimetidine	Multidrug and toxin extrusion protein 1	transporter
Cimetidine	Solute carrier family 22 member 4	transporter
Cimetidine	Solute carrier family 22 member 11	transporter
Cimetidine	Solute carrier family 22 member 7	transporter
Cimetidine	Cytochrome P450 11B1, mitochondrial	enzyme
Cimetidine	Cytochrome P450 2C8	enzyme
Cimetidine	Cytochrome P450 2C9	enzyme
Cimetidine	Cytochrome P450 2E1	enzyme
Cimetidine	Flavin-containing monooxygenase 3	enzyme
Cimetidine	Flavin-containing monooxygenase 1	enzyme
Cimetidine	Bile salt export pump	transporter
Cimetidine	Multidrug and toxin extrusion protein 2	transporter
Cimetidine	Albumin	carrier
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit A	target
Ciprofloxacin	DNA topoisomerase 2-alpha	target
Ciprofloxacin	Cytochrome P450 1A2	enzyme
Ciprofloxacin	Cytochrome P450 3A4	enzyme
Ciprofloxacin	Cytochrome P450 3A5	enzyme
Ciprofloxacin	Cytochrome P450 3A7	enzyme
Ciprofloxacin	ATP-dependent translocase ABCB1	transporter
Ciprofloxacin	Potassium voltage-gated channel subfamily H member 2	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit B	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	Multidrug resistance protein MdtK	target
Ciprofloxacin	Gyrase A	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	Multidrug and toxin extrusion protein 1	transporter
Ciprofloxacin	Multidrug and toxin extrusion protein 2	transporter
Ciprofloxacin	Albumin	carrier
Ciprofloxacin	Thymidylate synthase	target
Ciprofloxacin	DNA gyrase subunit B	target
Fluvoxamine	Sodium-dependent serotonin transporter	target
Fluvoxamine	Cytochrome P450 1A2	enzyme
Fluvoxamine	Cytochrome P450 2D6	enzyme
Fluvoxamine	Cytochrome P450 2C9	enzyme
Fluvoxamine	Cytochrome P450 2C19	enzyme
Fluvoxamine	Cytochrome P450 1A1	enzyme
Fluvoxamine	Cytochrome P450 3A4	enzyme
Fluvoxamine	Cytochrome P450 3A Subfamily	enzyme
Fluvoxamine	ATP-dependent translocase ABCB1	transporter
Fluvoxamine	Cytochrome P450 2B6	enzyme
Fluvoxamine	Potassium voltage-gated channel subfamily H member 2	target
Fluvoxamine	Bile salt export pump	transporter
Prasterone	Cytochrome P450 3A7	enzyme
Prasterone	Peroxisome proliferator-activated receptor alpha	target
Prasterone	Estrogen receptor	target
Prasterone	Sigma non-opioid intracellular receptor 1	target
Prasterone	Estrogen receptor beta	target
Prasterone	Nuclear receptor subfamily 1 group I member 2	target
Prasterone	Nuclear receptor subfamily 1 group I member 3	target
Prasterone	GABA(A) Receptor	target
Prasterone	NMDA receptor	target
Prasterone	Androgen receptor	target
Prasterone	17-beta-hydroxysteroid dehydrogenase type 1	enzyme
Prasterone	Sulfotransferase 2A1	enzyme
Prasterone	Sulfotransferase 2B1	enzyme
Prasterone	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	enzyme
Prasterone	Cholesterol oxidase	enzyme
Prasterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Prasterone	Solute carrier organic anion transporter family member 1B3	transporter
Prasterone	Solute carrier organic anion transporter family member 2B1	transporter
Prasterone	Solute carrier organic anion transporter family member 1B1	transporter
Prasterone	Solute carrier organic anion transporter family member 1A2	transporter
Prasterone	Multidrug resistance-associated protein 1	transporter
Prasterone	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Prasterone	ATP-binding cassette sub-family C member 4	transporter
Prasterone	Glucose-6-phosphate 1-dehydrogenase	target
Progesterone	Progesterone receptor	target
Progesterone	Estrogen receptor	target
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Progesterone	Cytochrome P450 2C19	enzyme
Progesterone	Cytochrome P450 2C9	enzyme
Progesterone	Cytochrome P450 3A4	enzyme
Progesterone	Cytochrome P450 3A5	enzyme
Progesterone	Cytochrome P450 3A7	enzyme
Progesterone	ATP-dependent translocase ABCB1	transporter
Progesterone	Solute carrier family 22 member 2	transporter
Progesterone	Solute carrier family 22 member 1	transporter
Progesterone	Solute carrier family 22 member 3	transporter
Progesterone	Bile salt export pump	transporter
Progesterone	Multidrug resistance-associated protein 1	transporter
Progesterone	Hepatic sodium/bile acid cotransporter	transporter
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Progesterone	Cytochrome P450 1A1	enzyme
Progesterone	Cytochrome P450 1B1	enzyme
Progesterone	Cytochrome P450 2A6	enzyme
Progesterone	Cytochrome P450 2D6	enzyme
Progesterone	Mineralocorticoid receptor	target
Progesterone	Kappa-type opioid receptor	target
Progesterone	Alpha-1-acid glycoprotein 1	target
Progesterone	Glucocorticoid receptor	target
Progesterone	Androgen receptor	target
Progesterone	Sex hormone-binding globulin	target
Progesterone	Solute carrier organic anion transporter family member 1B1	transporter
Progesterone	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Progesterone	Estrogen receptor beta	target
Progesterone	Solute carrier organic anion transporter family member 1B3	transporter
Cobicistat	Cytochrome P450 2D6	enzyme
Cobicistat	ATP-dependent translocase ABCB1	transporter
Cobicistat	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Cobicistat	Cytochrome P450 3A5	enzyme
Cobicistat	Cytochrome P450 3A7	enzyme
Cobicistat	Solute carrier organic anion transporter family member 1B1	transporter
Cobicistat	Solute carrier organic anion transporter family member 1B3	transporter
Cobicistat	Cytochrome P450 3A4	target
Cobicistat	Cytochrome P450 3A4	enzyme
Cobicistat	Cytochrome P450 3A5	target
Cobicistat	Cytochrome P450 3A7	target
Nelfinavir	HIV-1 protease	target
Nelfinavir	Cytochrome P450 2C19	enzyme
Nelfinavir	Cytochrome P450 3A4	enzyme
Nelfinavir	Cytochrome P450 2B6	enzyme
Nelfinavir	Cytochrome P450 3A5	enzyme
Nelfinavir	Cytochrome P450 3A7	enzyme
Nelfinavir	ATP-dependent translocase ABCB1	transporter
Nelfinavir	Solute carrier family 22 member 1	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1A2	transporter
Nelfinavir	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1B1	transporter
Nelfinavir	Cytochrome P450 2D6	enzyme
Nelfinavir	Albumin	carrier
Nelfinavir	UDP-glucuronosyltransferase 1A1	enzyme
Nelfinavir	Solute carrier organic anion transporter family member 1B3	transporter
Nelfinavir	Solute carrier organic anion transporter family member 2B1	transporter
Nelfinavir	Bile salt export pump	transporter
Nelfinavir	Cytochrome P450 2C9	enzyme
Nelfinavir	Alpha-1-acid glycoprotein 1	carrier
Itraconazole	Cytochrome P450 3A4	enzyme
Itraconazole	Cytochrome P450 3A5	enzyme
Itraconazole	Cytochrome P450 3A7	enzyme
Itraconazole	Cytochrome P450 2B6	enzyme
Itraconazole	ATP-dependent translocase ABCB1	transporter
Itraconazole	Cytochrome P450 1A1	enzyme
Itraconazole	Cytochrome P450 2E1	enzyme
Itraconazole	Solute carrier organic anion transporter family member 2B1	transporter
Itraconazole	Cytochrome P450 3A Subfamily	enzyme
Itraconazole	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Itraconazole	Albumin	carrier
Itraconazole	Lanosterol 14-alpha demethylase	target
Itraconazole	Lanosterol 14-alpha demethylase	target
Ketoconazole	Cytochrome P450 3A4	enzyme
Ketoconazole	Cytochrome P450 2C9	enzyme
Ketoconazole	Cytochrome P450 2C19	enzyme
Ketoconazole	Cytochrome P450 3A5	enzyme
Ketoconazole	Cytochrome P450 1A2	enzyme
Ketoconazole	Cytochrome P450 2C8	enzyme
Ketoconazole	Cytochrome P450 1A1	enzyme
Ketoconazole	Cytochrome P450 2D6	enzyme
Ketoconazole	Bile salt export pump	transporter
Ketoconazole	ATP-dependent translocase ABCB1	transporter
Ketoconazole	Cytochrome P450 11B1, mitochondrial	enzyme
Ketoconazole	Cytochrome P450 1B1	enzyme
Ketoconazole	Cytochrome P450 2A6	enzyme
Ketoconazole	Cytochrome P450 2B6	enzyme
Ketoconazole	Lanosterol 14-alpha demethylase	target
Ketoconazole	Androgen receptor	target
Ketoconazole	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Ketoconazole	Steroid 21-hydroxylase	target
Ketoconazole	Potassium voltage-gated channel subfamily H member 2	target
Ketoconazole	Nuclear receptor subfamily 1 group I member 2	target
Ketoconazole	Nuclear receptor subfamily 1 group I member 3	target
Ketoconazole	UDP-glucuronosyltransferase 1A1	enzyme
Ketoconazole	UDP-glucuronosyltransferase 2B7	enzyme
Ketoconazole	Solute carrier organic anion transporter family member 1B1	transporter
Ketoconazole	Cytochrome P450 4F12	enzyme
Ketoconazole	Cytochrome P450 4F2	enzyme
Ketoconazole	Albumin	carrier
Ketoconazole	Sex hormone-binding globulin	carrier
Ketoconazole	Aromatase	enzyme
Ketoconazole	UDP-glucuronosyltransferase 1A7	enzyme
Ketoconazole	Lanosterol 14-alpha demethylase	target
Ritonavir	Pol polyprotein	target
Ritonavir	Cytochrome P450 2D6	enzyme
Ritonavir	Cytochrome P450 2C9	enzyme
Ritonavir	Cytochrome P450 2C19	enzyme
Ritonavir	Cytochrome P450 2B6	enzyme
Ritonavir	Cytochrome P450 2C8	enzyme
Ritonavir	ATP-dependent translocase ABCB1	transporter
Ritonavir	Multidrug resistance-associated protein 1	transporter
Ritonavir	ATP-binding cassette sub-family C member 2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1A2	transporter
Ritonavir	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1B1	transporter
Ritonavir	Cytochrome P450 1A2	enzyme
Ritonavir	Nuclear receptor subfamily 1 group I member 2	target
Ritonavir	Albumin	carrier
Ritonavir	Cytochrome P450 3A4	enzyme
Ritonavir	Cytochrome P450 3A5	enzyme
Ritonavir	Cytochrome P450 3A7	enzyme
Ritonavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Ritonavir	Solute carrier organic anion transporter family member 2B1	transporter
Ritonavir	Bile salt export pump	transporter
Ritonavir	Alpha-1-acid glycoprotein 1	carrier
Ritonavir	Solute carrier organic anion transporter family member 1B3	transporter
Ritonavir	Gag-Pol polyprotein	target
Troleandomycin	Cytochrome P450 3A5	enzyme
Troleandomycin	Cytochrome P450 3A43	enzyme
Troleandomycin	50S ribosomal protein L4	target
Troleandomycin	50S ribosomal protein L32	target
Troleandomycin	ATP-dependent translocase ABCB1	transporter
Troleandomycin	Cytochrome P450 2C8	enzyme
Troleandomycin	Cytochrome P450 3A4	enzyme
Troleandomycin	Nuclear receptor subfamily 1 group I member 2	target
Troleandomycin	Cytochrome P450 3A7	enzyme
Indinavir	Pol polyprotein	target
Indinavir	Cytochrome P450 3A4	enzyme
Indinavir	Cytochrome P450 3A5	enzyme
Indinavir	Cytochrome P450 3A7	enzyme
Indinavir	ATP-dependent translocase ABCB1	transporter
Indinavir	Solute carrier family 22 member 1	transporter
Indinavir	Multidrug resistance-associated protein 1	transporter
Indinavir	Solute carrier organic anion transporter family member 1A2	transporter
Indinavir	Solute carrier organic anion transporter family member 1B1	transporter
Indinavir	ATP-binding cassette sub-family C member 2	transporter
Indinavir	Cytochrome P450 2D6	enzyme
Indinavir	UDP-glucuronosyltransferase 1A1	enzyme
Indinavir	Solute carrier organic anion transporter family member 2B1	transporter
Indinavir	Bile salt export pump	transporter
Indinavir	Gag-Pol polyprotein	target
Saquinavir	Pol polyprotein	target
Saquinavir	Cytochrome P450 3A4	enzyme
Saquinavir	Cytochrome P450 3A5	enzyme
Saquinavir	Alpha-1-acid glycoprotein 1	carrier
Saquinavir	Albumin	carrier
Saquinavir	Cytochrome P450 3A7	enzyme
Saquinavir	ATP-dependent translocase ABCB1	transporter
Saquinavir	Solute carrier family 22 member 1	transporter
Saquinavir	Solute carrier organic anion transporter family member 1A2	transporter
Saquinavir	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Saquinavir	Solute carrier organic anion transporter family member 1B1	transporter
Saquinavir	Multidrug resistance-associated protein 1	transporter
Saquinavir	ATP-binding cassette sub-family C member 2	transporter
Saquinavir	Cytochrome P450 2C8	enzyme
Saquinavir	Cytochrome P450 2D6	enzyme
Saquinavir	Solute carrier organic anion transporter family member 2B1	transporter
Saquinavir	Bile salt export pump	transporter
Saquinavir	Gag-Pol polyprotein	target
Aprepitant	Substance-P receptor	target
Aprepitant	Cytochrome P450 3A4	enzyme
Aprepitant	Cytochrome P450 2C9	enzyme
Aprepitant	Cytochrome P450 2C19	enzyme
Imatinib	Platelet-derived growth factor receptor beta	target
Imatinib	Tyrosine-protein kinase ABL1	target
Imatinib	Mast/stem cell growth factor receptor Kit	target
Imatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Imatinib	High affinity nerve growth factor receptor	target
Imatinib	Macrophage colony-stimulating factor 1 receptor	target
Imatinib	Platelet-derived growth factor receptor alpha	target
Imatinib	Epithelial discoidin domain-containing receptor 1	target
Imatinib	Cytochrome P450 3A4	enzyme
Imatinib	Breakpoint cluster region protein	target
Imatinib	Cytochrome P450 1A2	enzyme
Imatinib	Cytochrome P450 2D6	enzyme
Imatinib	Cytochrome P450 2C9	enzyme
Imatinib	Cytochrome P450 2C19	enzyme
Imatinib	Cytochrome P450 3A5	enzyme
Imatinib	Cytochrome P450 3A7	enzyme
Imatinib	Solute carrier family 22 member 1	transporter
Imatinib	ATP-dependent translocase ABCB1	transporter
Imatinib	Solute carrier family 22 member 2	transporter
Imatinib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Imatinib	Phospholipid-transporting ATPase ABCA3	transporter
Imatinib	Albumin	carrier
Imatinib	Alpha-1-acid glycoprotein 1	carrier
Imatinib	Bile salt export pump	transporter
Imatinib	Cytochrome P450 2C8	enzyme
Imatinib	ATP-binding cassette sub-family C member 2	transporter
Imatinib	Multidrug resistance-associated protein 1	transporter
Imatinib	Organic cation/carnitine transporter 2	transporter
Imatinib	Solute carrier organic anion transporter family member 1B3	transporter
Imatinib	ATP-binding cassette sub-family C member 4	transporter
Imatinib	Solute carrier organic anion transporter family member 1A2	transporter
Imatinib	Discoidin domain-containing receptor 2	target
Imatinib	Induced myeloid leukemia cell differentiation protein Mcl-1	target
Chloramphenicol	Complement decay-accelerating factor	target
Chloramphenicol	Dr hemagglutinin structural subunit	target
Chloramphenicol	Cytochrome P450 2C19	enzyme
Chloramphenicol	Cytochrome P450 3A4	enzyme
Chloramphenicol	Cytochrome P450 3A5	enzyme
Chloramphenicol	Cytochrome P450 3A7	enzyme
Chloramphenicol	Solute carrier family 22 member 6	transporter
Chloramphenicol	50S ribosomal protein L16	target
Chloramphenicol	Chloramphenicol acetyltransferase 3	enzyme
Chloramphenicol	Chloramphenicol acetyltransferase	enzyme
Chloramphenicol	Chloramphenicol 3-O phosphotransferase	enzyme
Delavirdine	Cytochrome P450 3A4	enzyme
Delavirdine	Cytochrome P450 2C9	enzyme
Delavirdine	Cytochrome P450 2D6	enzyme
Delavirdine	Cytochrome P450 3A5	enzyme
Delavirdine	Cytochrome P450 3A7	enzyme
Delavirdine	Cytochrome P450 2C19	enzyme
Delavirdine	Reverse transcriptase/RNaseH	target
Delavirdine	Gag-Pol polyprotein	target
Gestodene	Cytochrome P450 3A5	enzyme
Gestodene	Cytochrome P450 3A7	enzyme
Gestodene	Progesterone receptor	target
Gestodene	Cytochrome P450 3A4	enzyme
Gestodene	Cytochrome P450 2C19	enzyme
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-1	target
Mibefradil	Cytochrome P450 3A4	enzyme
Mibefradil	Cytochrome P450 1A2	enzyme
Mibefradil	Cytochrome P450 2D6	enzyme
Mibefradil	Cytochrome P450 3A5	enzyme
Mibefradil	Cytochrome P450 3A7	enzyme
Mibefradil	ATP-dependent translocase ABCB1	transporter
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1F	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-2	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-3	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-4	target
Mibefradil	Cytochrome P450 11B1, mitochondrial	enzyme
Mibefradil	Cytochrome P450 11B2, mitochondrial	enzyme
Mifepristone	Progesterone receptor	target
Mifepristone	Glucocorticoid receptor	target
Mifepristone	Cytochrome P450 3A4	enzyme
Mifepristone	Cytochrome P450 3A5	enzyme
Mifepristone	ATP-dependent translocase ABCB1	transporter
Mifepristone	Multidrug resistance-associated protein 1	transporter
Mifepristone	Cytochrome P450 2D6	enzyme
Mifepristone	Prostate-specific antigen	target
Mifepristone	Nuclear receptor subfamily 1 group I member 2	target
Mifepristone	Bile salt export pump	transporter
Mifepristone	Cytochrome P450 2C8	enzyme
Mifepristone	Cytochrome P450 2C9	enzyme
Mifepristone	Solute carrier organic anion transporter family member 1B1	transporter
Mifepristone	Solute carrier organic anion transporter family member 1B3	transporter
Norfloxacin	DNA gyrase subunit A	target
Norfloxacin	DNA topoisomerase 4 subunit A	target
Norfloxacin	DNA topoisomerase 2-alpha	target
Norfloxacin	Cytochrome P450 1A2	enzyme
Norfloxacin	Cytochrome P450 3A4	enzyme
Norfloxacin	Organic cation/carnitine transporter 2	transporter
Norfloxacin	Solute carrier family 22 member 6	transporter
Norfloxacin	Cytochrome P450 1A1	enzyme
Norfloxacin	Cytochrome P450 3A7	enzyme
Norfloxacin	DNA gyrase subunit A	target
Norfloxacin	DNA topoisomerase 2	target
Norfloxacin	DNA topoisomerase 4 subunit A	target
Norfloxacin	DNA gyrase subunit B	target
Seproxetine	Cytochrome P450 3A5	enzyme
Seproxetine	Cytochrome P450 3A7	enzyme
Seproxetine	Cytochrome P450 2C9	enzyme
Seproxetine	Cytochrome P450 2C19	enzyme
Seproxetine	Cytochrome P450 3A4	enzyme
Seproxetine	Sodium-dependent noradrenaline transporter	target
Seproxetine	Sodium-dependent serotonin transporter	target
Seproxetine	Sodium-dependent dopamine transporter	target
Voriconazole	Cytochrome P450 2C19	enzyme
Voriconazole	Cytochrome P450 3A4	enzyme
Voriconazole	Cytochrome P450 2C9	enzyme
Voriconazole	Flavin-containing monooxygenase 1	enzyme
Voriconazole	Flavin-containing monooxygenase 3	enzyme
Voriconazole	Cytochrome P450 3A5	enzyme
Voriconazole	Cytochrome P450 3A7	enzyme
Voriconazole	Prostaglandin G/H synthase 1	enzyme
Voriconazole	Lanosterol 14-alpha demethylase	target
Voriconazole	Cytochrome P450 2B6	enzyme
Phenelzine	Amine oxidase [copper-containing] 3	target
Phenelzine	Amine oxidase [flavin-containing] B	target
Phenelzine	Amine oxidase [flavin-containing] A	target
Phenelzine	Amine oxidase [flavin-containing] A	enzyme
Phenelzine	Amine oxidase [flavin-containing] B	enzyme
Phenelzine	Cytochrome P450 2E1	enzyme
Phenelzine	4-aminobutyrate aminotransferase, mitochondrial	target
Phenelzine	Glutamic acid decarboxylase	target
Phenelzine	Alanine aminotransferase 1	target
Phenelzine	Alanine aminotransferase 2	target
Phenelzine	Cytochrome P450 2C19	enzyme
Phenelzine	Cytochrome P450 2C8	enzyme
Phenelzine	Cytochrome P450 3A4	enzyme
Phenelzine	Cytochrome P450 3A5	enzyme
Phenelzine	Cytochrome P450 3A7	enzyme
Phenelzine	Cytochrome P450 2D6	enzyme
Phenelzine	Cytochrome P450 3A Subfamily	enzyme
Troglitazone	Peroxisome proliferator-activated receptor gamma	target
Troglitazone	Long-chain-fatty-acid--CoA ligase 4	target
Troglitazone	Plasminogen activator inhibitor 1	target
Troglitazone	Equilibrative nucleoside transporter 1	target
Troglitazone	Cytochrome P450 3A4	enzyme
Troglitazone	Cytochrome P450 2C19	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A1	enzyme
Troglitazone	Cytochrome P450 2C8	enzyme
Troglitazone	Bile salt export pump	transporter
Troglitazone	Solute carrier organic anion transporter family member 1B1	transporter
Troglitazone	Estrogen-related receptor gamma	target
Troglitazone	Steroid hormone receptor ERR1	target
Troglitazone	Aromatase	enzyme
Troglitazone	Cytochrome P450 1A1	enzyme
Troglitazone	Cytochrome P450 2B6	enzyme
Troglitazone	Cytochrome P450 2C9	enzyme
Troglitazone	Cytochrome P450 3A5	enzyme
Troglitazone	Cytochrome P450 3A7	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A3	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A4	enzyme
Troglitazone	UDP-glucuronosyltransferase 1-6	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A7	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A8	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A9	enzyme
Troglitazone	UDP-glucuronosyltransferase 1A10	enzyme
Troglitazone	UDP-glucuronosyltransferase 2B7	enzyme
Troglitazone	UDP-glucuronosyltransferase 2B15	enzyme
Troglitazone	Peroxisome proliferator-activated receptor delta	target
Troglitazone	Peroxisome proliferator-activated receptor alpha	target
Troglitazone	Glutathione S-transferase P	target
Idelalisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Idelalisib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Idelalisib	ATP-dependent translocase ABCB1	transporter
Idelalisib	Aldehyde oxidase	enzyme
Idelalisib	Cytochrome P450 2C8	enzyme
Idelalisib	Cytochrome P450 2C19	enzyme
Idelalisib	Cytochrome P450 2B6	enzyme
Idelalisib	Cytochrome P450 3A4	enzyme
Idelalisib	Solute carrier organic anion transporter family member 1B1	transporter
Idelalisib	Solute carrier organic anion transporter family member 1B3	transporter
Idelalisib	Cytochrome P450 3A5	enzyme
Idelalisib	Cytochrome P450 3A43	enzyme
Idelalisib	Cytochrome P450 3A7	enzyme
Idelalisib	UDP-glucuronosyltransferase 1A4	enzyme
Oxymetholone	Androgen receptor	target
Oxymetholone	Albumin	carrier
Oxymetholone	Sex hormone-binding globulin	carrier
Oxymetholone	Natriuretic peptides B	target
Oxymetholone	Amine oxidase [flavin-containing] A	enzyme
Oxymetholone	Cytochrome P450 2D6	enzyme
Oxymetholone	3-oxo-5-alpha-steroid 4-dehydrogenase 1	enzyme
Oxymetholone	Cytochrome P450 3A4	enzyme
Oxymetholone	Cytochrome P450 3A5	enzyme
Oxymetholone	Cytochrome P450 3A7	enzyme
Oxymetholone	Cytochrome P450 3A43	enzyme
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Protein mono-ADP-ribosyltransferase PARP3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	ATP-dependent translocase ABCB1	transporter
Rucaparib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	ATP-binding cassette sub-family C member 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Organic anion transporter 3	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1A1	enzyme
Letermovir	UDP-glucuronosyltransferase 1A1	enzyme
Letermovir	UDP-glucuronosyltransferase 1A3	enzyme
Letermovir	Solute carrier organic anion transporter family member 1B1	transporter
Letermovir	Solute carrier organic anion transporter family member 1B3	transporter
Letermovir	Cytochrome P450 2D6	enzyme
Letermovir	Cytochrome P450 2C8	enzyme
Letermovir	Cytochrome P450 2C19	enzyme
Letermovir	Cytochrome P450 2C9	enzyme
Letermovir	Cytochrome P450 2B6	enzyme
Letermovir	ATP-dependent translocase ABCB1	transporter
Letermovir	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Letermovir	Bile salt export pump	transporter
Letermovir	Organic anion transporter 3	transporter
Letermovir	ATP-binding cassette sub-family C member 2	transporter
Letermovir	CMV DNA Terminase Complex	target
Letermovir	Cytochrome P450 3A Subfamily	enzyme
Diltiazem	Voltage-dependent calcium channel gamma-1 subunit	target
Diltiazem	Cytochrome P450 3A4	enzyme
Diltiazem	Cytochrome P450 2C19	enzyme
Diltiazem	Cytochrome P450 2D6	enzyme
Diltiazem	Cytochrome P450 3A5	enzyme
Diltiazem	Cytochrome P450 3A7	enzyme
Diltiazem	ATP-dependent translocase ABCB1	transporter
Diltiazem	Cytochrome P450 2C8	enzyme
Diltiazem	Albumin	carrier
Diltiazem	Alpha-1-acid glycoprotein 1	carrier
Diltiazem	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Diltiazem	Voltage-dependent calcium channel subunit alpha-2/delta-1	target
Cannabidiol	Cytochrome P450 2C9	enzyme
Cannabidiol	Cytochrome P450 2C19	enzyme
Cannabidiol	Cytochrome P450 2D6	enzyme
Cannabidiol	Cytochrome P450 3A4	enzyme
Cannabidiol	Cannabinoid receptor 1	target
Cannabidiol	Cannabinoid receptor 2	target
Cannabidiol	G-protein coupled receptor 12	target
Cannabidiol	Glycine receptor subunit alpha-1	target
Cannabidiol	Glycine receptor (alpha-1/beta)	target
Cannabidiol	Glycine receptor subunit alpha-3	target
Cannabidiol	N-arachidonyl glycine receptor	target
Cannabidiol	G-protein coupled receptor 55	target
Cannabidiol	5-hydroxytryptamine receptor 1A	target
Cannabidiol	5-hydroxytryptamine receptor 2A	target
Cannabidiol	Neuronal acetylcholine receptor subunit alpha-7	target
Cannabidiol	Delta-type opioid receptor	target
Cannabidiol	Mu-type opioid receptor	target
Cannabidiol	Peroxisome proliferator-activated receptor gamma	target
Cannabidiol	Cytochrome P450 3A5	enzyme
Cannabidiol	Serotonin N-acetyltransferase	enzyme
Cannabidiol	Cytochrome P450 1A1	enzyme
Cannabidiol	Fatty-acid amide hydrolase 1	enzyme
Cannabidiol	Polyunsaturated fatty acid 5-lipoxygenase	enzyme
Cannabidiol	Polyunsaturated fatty acid lipoxygenase ALOX15	enzyme
Cannabidiol	Quinone oxidoreductase	enzyme
Cannabidiol	Multidrug resistance-associated protein 1	transporter
Cannabidiol	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Cannabidiol	Equilibrative nucleoside transporter 1	transporter
Cannabidiol	Transient receptor potential cation channel subfamily V member 1	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Cannabidiol	Transient receptor potential cation channel subfamily A member 1	target
Cannabidiol	Transient receptor potential cation channel subfamily M member 8	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 2	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 3	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 4	target
Cannabidiol	Non-selective voltage-gated ion channel VDAC1	target
Cannabidiol	5-hydroxytryptamine receptor 3A	target
Cannabidiol	Adenosine receptor A1	target
Cannabidiol	Prostaglandin G/H synthase 1	target
Cannabidiol	Prostaglandin G/H synthase 2	target
Cannabidiol	Acetyl-CoA acetyltransferase, mitochondrial	target
Cannabidiol	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Cannabidiol	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Cannabidiol	Glutathione reductase, mitochondrial	target
Cannabidiol	Glutathione peroxidase 1	target
Cannabidiol	Indoleamine 2,3-dioxygenase 1	target
Cannabidiol	Cytochrome P450 1B1	target
Cannabidiol	NAD(P)H dehydrogenase [quinone] 1	target
Cannabidiol	Catalase	target
Cannabidiol	Cytochrome P450 3A5	target
Cannabidiol	Cytochrome P450 2D6	target
Cannabidiol	Superoxide dismutase [Cu-Zn]	target
Cannabidiol	Cytochrome P450 1A2	target
Cannabidiol	Cytochrome P450 3A7	target
Cannabidiol	Serotonin N-acetyltransferase	target
Cannabidiol	N-acylethanolamine-hydrolyzing acid amidase	target
Cannabidiol	Cytochrome P450 1A2	enzyme
Cannabidiol	Cytochrome P450 1B1	enzyme
Cannabidiol	Cytochrome P450 2A6	enzyme
Cannabidiol	Cytochrome P450 2B6	enzyme
Cannabidiol	Cytochrome P450 2C8	enzyme
Cannabidiol	Cytochrome P450 2E1	enzyme
Cannabidiol	Cytochrome P450 3A7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 1A7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 1A9	enzyme
Cannabidiol	UDP-glucuronosyltransferase 2B7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 2B17	enzyme
Cannabidiol	ATP-dependent translocase ABCB1	transporter
Cannabidiol	Cytochrome P450 2J2	enzyme
Cannabidiol	Liver carboxylesterase 1	enzyme
Medical Cannabis	Cannabinoid receptor 1	target
Medical Cannabis	Cannabinoid receptor 2	target
Medical Cannabis	Cytochrome P450 2C9	enzyme
Medical Cannabis	Cytochrome P450 2C19	enzyme
Medical Cannabis	Cytochrome P450 2D6	enzyme
Medical Cannabis	Cytochrome P450 3A4	enzyme
Medical Cannabis	G-protein coupled receptor 12	target
Medical Cannabis	Glycine receptor subunit alpha-1	target
Medical Cannabis	Glycine receptor (alpha-1/beta)	target
Medical Cannabis	Glycine receptor subunit alpha-3	target
Medical Cannabis	N-arachidonyl glycine receptor	target
Medical Cannabis	G-protein coupled receptor 55	target
Medical Cannabis	5-hydroxytryptamine receptor 1A	target
Medical Cannabis	5-hydroxytryptamine receptor 2A	target
Medical Cannabis	Neuronal acetylcholine receptor subunit alpha-7	target
Medical Cannabis	Delta-type opioid receptor	target
Medical Cannabis	Mu-type opioid receptor	target
Medical Cannabis	Peroxisome proliferator-activated receptor gamma	target
Medical Cannabis	Cytochrome P450 3A5	enzyme
Medical Cannabis	Cytochrome P450 3A7	enzyme
Medical Cannabis	Cytochrome P450 1A1	enzyme
Medical Cannabis	Cytochrome P450 1A2	enzyme
Medical Cannabis	Cytochrome P450 1B1	enzyme
Medical Cannabis	Polyunsaturated fatty acid 5-lipoxygenase	enzyme
Medical Cannabis	Polyunsaturated fatty acid lipoxygenase ALOX15	enzyme
Medical Cannabis	Superoxide dismutase [Cu-Zn]	enzyme
Medical Cannabis	Multidrug resistance-associated protein 1	transporter
Medical Cannabis	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Medical Cannabis	Equilibrative nucleoside transporter 1	transporter
Medical Cannabis	Transient receptor potential cation channel subfamily V member 1	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Medical Cannabis	Transient receptor potential cation channel subfamily A member 1	target
Medical Cannabis	Transient receptor potential cation channel subfamily M member 8	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 2	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 3	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 4	target
Medical Cannabis	Non-selective voltage-gated ion channel VDAC1	target
Medical Cannabis	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	target
Medical Cannabis	N-acylethanolamine-hydrolyzing acid amidase	target
Medical Cannabis	Serotonin N-acetyltransferase	target
Medical Cannabis	Phospholipase A2	target
Medical Cannabis	Superoxide dismutase [Cu-Zn]	target
Medical Cannabis	Fatty-acid amide hydrolase 1	target
Medical Cannabis	Catalase	target
Medical Cannabis	Quinone oxidoreductase	target
Medical Cannabis	Sphingomyelin phosphodiesterase	target
Medical Cannabis	Glutathione peroxidase 1	target
Medical Cannabis	Glutathione reductase, mitochondrial	target
Medical Cannabis	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Medical Cannabis	Indoleamine 2,3-dioxygenase 1	target
Medical Cannabis	Prostaglandin G/H synthase 1	target
Medical Cannabis	Prostaglandin G/H synthase 2	target
Medical Cannabis	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Medical Cannabis	Acetyl-CoA acetyltransferase, mitochondrial	target
Medical Cannabis	Cytochrome P450 2A6	enzyme
Medical Cannabis	Cytochrome P450 2B6	enzyme
Medical Cannabis	Cytochrome P450 2C8	enzyme
Medical Cannabis	Cytochrome P450 2E1	enzyme
Medical Cannabis	Cytochrome P450 2J2	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1A7	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1A8	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1A9	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1A10	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 2B17	enzyme
Medical Cannabis	Liver carboxylesterase 1	enzyme
Medical Cannabis	ATP-dependent translocase ABCB1	transporter
Medical Cannabis	UDP-glucuronosyltransferase 2B7	enzyme
Nabiximols	Cannabinoid receptor 1	target
Nabiximols	Cannabinoid receptor 2	target
Nabiximols	G-protein coupled receptor 12	target
Nabiximols	Cytochrome P450 2C9	enzyme
Nabiximols	Cytochrome P450 2C19	enzyme
Nabiximols	Cytochrome P450 2D6	enzyme
Nabiximols	Cytochrome P450 3A4	enzyme
Nabiximols	Glycine receptor subunit alpha-1	target
Nabiximols	Glycine receptor (alpha-1/beta)	target
Nabiximols	Glycine receptor subunit alpha-3	target
Nabiximols	N-arachidonyl glycine receptor	target
Nabiximols	G-protein coupled receptor 55	target
Nabiximols	5-hydroxytryptamine receptor 1A	target
Nabiximols	5-hydroxytryptamine receptor 2A	target
Nabiximols	Neuronal acetylcholine receptor subunit alpha-7	target
Nabiximols	Delta-type opioid receptor	target
Nabiximols	Mu-type opioid receptor	target
Nabiximols	Peroxisome proliferator-activated receptor gamma	target
Nabiximols	Cytochrome P450 3A5	enzyme
Nabiximols	Polyunsaturated fatty acid 5-lipoxygenase	enzyme
Nabiximols	Polyunsaturated fatty acid lipoxygenase ALOX15	enzyme
Nabiximols	Multidrug resistance-associated protein 1	transporter
Nabiximols	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Nabiximols	Equilibrative nucleoside transporter 1	transporter
Nabiximols	Transient receptor potential cation channel subfamily V member 1	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Nabiximols	Transient receptor potential cation channel subfamily A member 1	target
Nabiximols	Transient receptor potential cation channel subfamily M member 8	target
Nabiximols	Transient receptor potential cation channel subfamily V member 2	target
Nabiximols	Transient receptor potential cation channel subfamily V member 3	target
Nabiximols	Transient receptor potential cation channel subfamily V member 4	target
Nabiximols	Non-selective voltage-gated ion channel VDAC1	target
Nabiximols	Prostaglandin G/H synthase 1	target
Nabiximols	Prostaglandin G/H synthase 2	target
Nabiximols	Acetyl-CoA acetyltransferase, mitochondrial	target
Nabiximols	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Nabiximols	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Nabiximols	Glutathione reductase, mitochondrial	target
Nabiximols	Glutathione peroxidase 1	target
Nabiximols	Indoleamine 2,3-dioxygenase 1	target
Nabiximols	Serotonin N-acetyltransferase	target
Nabiximols	Cytochrome P450 1B1	target
Nabiximols	Cytochrome P450 3A5	target
Nabiximols	Cytochrome P450 2D6	target
Nabiximols	Cytochrome P450 1A2	target
Nabiximols	Cytochrome P450 1A1	target
Nabiximols	Cytochrome P450 3A7	target
Nabiximols	Quinone oxidoreductase	target
Nabiximols	Catalase	target
Nabiximols	Fatty-acid amide hydrolase 1	target
Nabiximols	Superoxide dismutase [Cu-Zn]	target
Nabiximols	N-acylethanolamine-hydrolyzing acid amidase	target
Menadione	Prothrombin	target
Menadione	Vitamin K epoxide reductase complex subunit 1	target
Menadione	Coagulation factor IX	target
Menadione	Vitamin K-dependent gamma-carboxylase	target
Menadione	Vitamin K-dependent protein C	target
Menadione	Vitamin K-dependent protein S	target
Menadione	NAD(P)H dehydrogenase [quinone] 1	target
Menadione	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Menadione	Vitamin K epoxide reductase complex subunit 1-like protein 1	target
Menadione	Xanthine dehydrogenase/oxidase	enzyme
Menadione	Aldehyde oxidase	enzyme
Menadione	Methylenetetrahydrofolate reductase (NADPH)	enzyme
Menadione	Cytochrome P450 1A1	enzyme
Menadione	Osteocalcin	target
Menadione	Cytochrome P450 1A2	enzyme
Menadione	Cytochrome P450 2A6	enzyme
Menadione	Cytochrome P450 1B1	enzyme
Menadione	Cytochrome P450 2B6	enzyme
Menadione	Cytochrome P450 2C8	enzyme
Menadione	Cytochrome P450 2C9	enzyme
Menadione	Cytochrome P450 2C19	enzyme
Menadione	Cytochrome P450 2D6	enzyme
Menadione	Cytochrome P450 2E1	enzyme
Menadione	Cytochrome P450 3A4	enzyme
Menadione	Cytochrome P450 3A5	enzyme
Menadione	Cytochrome P450 3A7	enzyme
Menadione	Aldehyde oxidase	target
Dronabinol	Cannabinoid receptor 1	target
Dronabinol	Cytochrome P450 3A4	enzyme
Dronabinol	Cytochrome P450 2C9	enzyme
Dronabinol	Cannabinoid receptor 2	target
Dronabinol	ATP-dependent translocase ABCB1	transporter
Dronabinol	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Dronabinol	Prostaglandin G/H synthase 1	enzyme
Dronabinol	Cytochrome P450 2C19	enzyme
Dronabinol	Cytochrome P450 1A1	enzyme
Dronabinol	Cytochrome P450 1A2	enzyme
Dronabinol	Cytochrome P450 1B1	enzyme
Dronabinol	Cytochrome P450 2A6	enzyme
Dronabinol	Cytochrome P450 2B6	enzyme
Dronabinol	Cytochrome P450 2D6	enzyme
Dronabinol	Cytochrome P450 2J2	enzyme
Dronabinol	Cytochrome P450 3A5	enzyme
Dronabinol	Cytochrome P450 3A7	enzyme
Dronabinol	Multidrug resistance-associated protein 1	transporter
Dronabinol	Liver carboxylesterase 1	enzyme
Dronabinol	UDP-glucuronosyltransferase 1A1	enzyme
Dronabinol	UDP-glucuronosyltransferase 1A3	enzyme
Dronabinol	UDP-glucuronosyltransferase 1A9	enzyme
Dronabinol	UDP-glucuronosyltransferase 1A10	enzyme
Cannabinol	Cytochrome P450 3A4	enzyme
Cannabinol	Cytochrome P450 2C19	enzyme
Cannabinol	Cytochrome P450 1A1	enzyme
Cannabinol	Cytochrome P450 1A2	enzyme
Cannabinol	Cytochrome P450 1B1	enzyme
Cannabinol	Cytochrome P450 2A6	enzyme
Cannabinol	Cytochrome P450 2B6	enzyme
Cannabinol	Cytochrome P450 2C9	enzyme
Cannabinol	Cytochrome P450 2D6	enzyme
Cannabinol	Cytochrome P450 3A5	enzyme
Cannabinol	Cytochrome P450 3A7	enzyme
Cannabinol	UDP-glucuronosyltransferase 1A7	enzyme
Cannabinol	UDP-glucuronosyltransferase 1A8	enzyme
Cannabinol	UDP-glucuronosyltransferase 1A9	enzyme
Cannabinol	UDP-glucuronosyltransferase 1A10	enzyme
Cannabinol	UDP-glucuronosyltransferase 2B7	enzyme
Cannabinol	ATP-dependent translocase ABCB1	transporter
Cannabinol	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Cannabinol	Multidrug resistance-associated protein 1	transporter
Cannabinol	Cytochrome P450 2E1	enzyme
Cannabinol	Cytochrome P450 2J2	enzyme
Cannabinol	Liver carboxylesterase 1	enzyme
Cannabinol	Cannabinoid receptor 1	target
Encorafenib	Cytochrome P450 3A4	enzyme
Encorafenib	Cytochrome P450 2C19	enzyme
Encorafenib	Cytochrome P450 2D6	enzyme
Encorafenib	Serine/threonine-protein kinase B-raf	target
Encorafenib	G1/S-specific cyclin-D1	target
Encorafenib	UDP-glucuronosyltransferase 1A1	enzyme
Encorafenib	Albumin	carrier
Encorafenib	Cytochrome P450 1A2	enzyme
Encorafenib	Cytochrome P450 2B6	enzyme
Encorafenib	Cytochrome P450 2C8	enzyme
Encorafenib	Cytochrome P450 2C9	enzyme
Encorafenib	Cytochrome P450 3A5	enzyme
Encorafenib	Cytochrome P450 3A7	enzyme
Encorafenib	ATP-dependent translocase ABCB1	transporter
Encorafenib	Solute carrier family 22 member 2	transporter
Encorafenib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
Encorafenib	Solute carrier family 22 member 6	transporter
Encorafenib	Organic anion transporter 3	transporter
Encorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Encorafenib	Solute carrier organic anion transporter family member 1B3	transporter
Encorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Encorafenib	Mitogen-activated protein kinase 8	target
Encorafenib	Mitogen-activated protein kinase 9	target
Encorafenib	Mitogen-activated protein kinase 10	target
Encorafenib	LIM domain kinase 1	target
Encorafenib	LIM domain kinase 2	target
Encorafenib	Dual specificity mitogen-activated protein kinase kinase 4	target
Encorafenib	Serine/threonine-protein kinase 36	target
Atazanavir	Pol polyprotein	target
Atazanavir	Cytochrome P450 3A4	enzyme
Atazanavir	Cytochrome P450 2C9	enzyme
Atazanavir	ATP-dependent translocase ABCB1	transporter
Atazanavir	Multidrug resistance-associated protein 1	transporter
Atazanavir	Albumin	carrier
Atazanavir	UDP-glucuronosyltransferase 1A1	enzyme
Atazanavir	Solute carrier organic anion transporter family member 1B1	transporter
Atazanavir	Solute carrier organic anion transporter family member 1B3	transporter
Atazanavir	Cytochrome P450 2C8	enzyme
Atazanavir	Bile salt export pump	transporter
Atazanavir	alpha1-acid glycoprotein	carrier
Atazanavir	Cytochrome P450 1A2	enzyme
Atazanavir	Solute carrier organic anion transporter family member 2B1	transporter
Atazanavir	Cytochrome P450 3A5	enzyme
Atazanavir	Cytochrome P450 3A7	enzyme
Atazanavir	Gag-Pol polyprotein	target