Narrow Therapeutic Index Drugs

DBCAT003972Pharmacologic class

Narrow therapeutic index (NTI) drugs are defined as those drugs where small differences in dose or blood concentration may lead to dose and blood concentration dependent, serious therapeutic failures or adverse drug reactions. Serious events... A DrugBank category of 253 drugs. 243 of them are approved.

Also known as: Drugs with Narrow Therapeutic Indexes · Drugs with Narrow Therapeutic Ranges · Narrow Therapeutic Range Drugs · NTI Drugs · NTID
Drugs: Abemaciclib
Acalabrutinib
Acenocoumarol
Alatrofloxacin
Aldesleukin
Alectinib
Alemtuzumab
Alpelisib
Altretamine
Amikacin
Amineptine
Aminoglutethimide
Aminophylline
Amiodarone
Amitriptyline
Amitriptylinoxide
Amoxapine
Amphotericin B
Amsacrine
Anagrelide
Arbekacin
Argatroban
Arsenic trioxide
Asparaginase Erwinia chrysanthemi
Asparaginase Escherichia coli
and 228 more with a free account

What you can answer from here — as of September 12, 2018

253DrugsEach linked to its full drug card

480Drug targetsEvery drug–target pair in the class, with bond type

34,379Marketed productsAcross the regions we cover, with dosage forms and routes

46Routes of administrationHow the drugs in this class are given

Which targets do Narrow Therapeutic Index Drugs share, and which companies have late-stage candidates in this class?

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