Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
- Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
- Accession Number
Drug Drug Description Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Carbamazepine An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Plazomicin An aminoglycoside antibiotic used to treat complicated urinary tract infections. Procainamide A medication used to treat life threatening ventricular arrhythmias. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Warfarin A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. Lithium carbonate A medication used to treat manic episodes of bipolar disorder. Pemetrexed A folate analog used to treat mesothelioma and non-small cell lung cancer. Cisplatin A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Netilmicin An aminoglycoside used to treat a wide variety of infections in the body. Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. Ribostamycin A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Gentamicin C1a Not Available Arbekacin Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Sisomicin Sisomicin has been used in trials studying the treatment of Pyoderma. Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . Micronomicin Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina. Isepamicin Not Annotated Bekanamycin An aminoglycoside antibiotic indicated in the treatment of eye infections. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Floxuridine An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy. Pentostatin An adenosine deaminase inhibitor used to treat hairy cell leukemia. Nedaplatin Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers .
- Drugs & Drug Targets