OATP2B1/SLCO2B1 substrates

Accession Number

DBCAT005523

Description

Not Available

Drugs

Drug	Drug Description
Pravastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
Diethylstilbestrol	Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
Conjugated estrogens	A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
Montelukast	A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
Dinoprostone	A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
Salicylic acid	An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Fexofenadine	A selective H1-antagonist for the symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria.
Glyburide	A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
Ibuprofen	An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
Benzylpenicillin	A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
Atorvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Iloprost	A synthetic prostacyclin analog used to treat pulmonary arterial hypertension (PAH) and frostbites.
Tolbutamide	A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Prasterone	A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
Acetic acid	An antimicrobial agent used to treat susceptible infections of the external auditory canal.
Taurocholic acid	The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
Lactic acid	An emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties.
Simeprevir	A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
Pitavastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Asunaprevir	An NS3 protease inhibitor used to treat hepatitis C genotype 1b.
Lifitegrast	A medication used to treat dry eye disease.
Opicapone	A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor.
Latanoprostene bunod	A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma.
Mesalazine	An aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
Elacestrant	An estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
Alprostadil	A prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis.

Drugs & Drug Targets

Drug	Target	Type
Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pravastatin	Solute carrier organic anion transporter family member 2B1	transporter
Pravastatin	P-glycoprotein 1	transporter
Pravastatin	Solute carrier organic anion transporter family member 1A2	transporter
Pravastatin	Solute carrier family 22 member 6	transporter
Pravastatin	Solute carrier family 22 member 8	transporter
Pravastatin	Canalicular multispecific organic anion transporter 1	transporter
Pravastatin	Solute carrier family 22 member 11	transporter
Pravastatin	ATP-binding cassette sub-family G member 2	transporter
Pravastatin	Solute carrier family 22 member 7	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B1	transporter
Pravastatin	Monocarboxylate transporter 1	transporter
Pravastatin	Bile salt export pump	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B3	transporter
Pravastatin	Histone deacetylase 2	target
Diethylstilbestrol	Estrogen receptor alpha	target
Diethylstilbestrol	Estrogen-related receptor gamma	target
Diethylstilbestrol	Transthyretin	carrier
Diethylstilbestrol	Catechol O-methyltransferase	enzyme
Diethylstilbestrol	Cytochrome P450 19A1	enzyme
Diethylstilbestrol	ATP-binding cassette sub-family G member 2	transporter
Diethylstilbestrol	P-glycoprotein 1	transporter
Diethylstilbestrol	Estrogen receptor beta	target
Diethylstilbestrol	Cytochrome P450 3A4	enzyme
Diethylstilbestrol	Cytochrome P450 2C8	enzyme
Diethylstilbestrol	Cytochrome P450 2C9	enzyme
Diethylstilbestrol	Cytochrome P450 2E1	enzyme
Diethylstilbestrol	Steroid hormone receptor ERR1	target
Diethylstilbestrol	Steroid hormone receptor ERR2	target
Diethylstilbestrol	Nuclear receptor coactivator 2	target
Diethylstilbestrol	Nuclear receptor subfamily 1 group I member 2	target
Diethylstilbestrol	Androgen receptor	target
Diethylstilbestrol	Sex hormone-binding globulin	target
Diethylstilbestrol	Solute carrier organic anion transporter family member 1B1	transporter
Diethylstilbestrol	Solute carrier organic anion transporter family member 2B1	transporter
Diethylstilbestrol	Bile salt export pump	transporter
Conjugated estrogens	Estrogen receptor alpha	target
Conjugated estrogens	Cytochrome P450 3A4	enzyme
Conjugated estrogens	Cytochrome P450 1A2	enzyme
Conjugated estrogens	Catechol O-methyltransferase	enzyme
Conjugated estrogens	Canalicular multispecific organic anion transporter 2	transporter
Conjugated estrogens	Multidrug resistance-associated protein 4	transporter
Conjugated estrogens	Multidrug resistance-associated protein 1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1A2	transporter
Conjugated estrogens	Sodium/bile acid cotransporter	transporter
Conjugated estrogens	Solute carrier family 22 member 10	transporter
Conjugated estrogens	Solute carrier family 22 member 8	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1C1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1B1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 2B1	transporter
Conjugated estrogens	P-glycoprotein 1	transporter
Conjugated estrogens	Solute carrier family 22 member 6	transporter
Conjugated estrogens	Organic solute transporter subunit alpha	transporter
Conjugated estrogens	Organic solute transporter subunit beta	transporter
Conjugated estrogens	Canalicular multispecific organic anion transporter 1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 4A1	transporter
Conjugated estrogens	ATP-binding cassette sub-family C member 11	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1B3	transporter
Conjugated estrogens	Solute carrier family 22 member 11	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 3A1	transporter
Conjugated estrogens	ATP-binding cassette sub-family G member 2	transporter
Conjugated estrogens	Thyroxine-binding globulin	carrier
Conjugated estrogens	Sex hormone-binding globulin	carrier
Conjugated estrogens	Serum albumin	carrier
Conjugated estrogens	Estrogen receptor beta	target
Montelukast	Cysteinyl leukotriene receptor 1	target
Montelukast	Arachidonate 5-lipoxygenase	target
Montelukast	Cytochrome P450 3A4	enzyme
Montelukast	Cytochrome P450 2C9	enzyme
Montelukast	Cytochrome P450 2C8	enzyme
Montelukast	Solute carrier organic anion transporter family member 2B1	transporter
Montelukast	Prostaglandin G/H synthase 1	enzyme
Montelukast	Cytochrome P450 2A6	enzyme
Dinoprostone	Prostaglandin E2 receptor EP2 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP1 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP4 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP3 subtype	target
Dinoprostone	Solute carrier family 22 member 2	transporter
Dinoprostone	Multidrug resistance-associated protein 5	transporter
Dinoprostone	Solute carrier family 22 member 6	transporter
Dinoprostone	Solute carrier family 22 member 8	transporter
Dinoprostone	Solute carrier family 22 member 11	transporter
Dinoprostone	Solute carrier family 22 member 7	transporter
Dinoprostone	Multidrug resistance-associated protein 4	transporter
Dinoprostone	Solute carrier organic anion transporter family member 2B1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1A2	transporter
Dinoprostone	Organic solute transporter subunit alpha	transporter
Dinoprostone	Organic solute transporter subunit beta	transporter
Dinoprostone	Solute carrier organic anion transporter family member 2A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 4A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1C1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 3A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1B1	transporter
Dinoprostone	Prostaglandin D2 receptor 2	target
Salicylic acid	Serum albumin	carrier
Salicylic acid	Prostaglandin G/H synthase 1	target
Salicylic acid	Prostaglandin G/H synthase 2	target
Salicylic acid	Aldo-keto reductase family 1 member C1	target
Salicylic acid	Solute carrier family 22 member 6	transporter
Salicylic acid	Solute carrier family 22 member 10	transporter
Salicylic acid	Solute carrier family 22 member 8	transporter
Salicylic acid	Solute carrier family 22 member 11	transporter
Salicylic acid	Solute carrier organic anion transporter family member 2B1	transporter
Salicylic acid	Monocarboxylate transporter 1	transporter
Salicylic acid	Solute carrier family 22 member 7	transporter
Salicylic acid	Cytochrome P450 2C9	enzyme
Fexofenadine	Histamine H1 receptor	target
Fexofenadine	P-glycoprotein 1	transporter
Fexofenadine	Solute carrier organic anion transporter family member 2B1	transporter
Fexofenadine	Solute carrier organic anion transporter family member 1A2	transporter
Fexofenadine	Solute carrier organic anion transporter family member 1B1	transporter
Fexofenadine	Solute carrier organic anion transporter family member 1B3	transporter
Fexofenadine	Solute carrier family 22 member 8	transporter
Fexofenadine	Canalicular multispecific organic anion transporter 1	transporter
Fexofenadine	Canalicular multispecific organic anion transporter 2	transporter
Fexofenadine	Serum albumin	carrier
Fexofenadine	alpha1-acid glycoprotein	carrier
Glyburide	ATP-binding cassette sub-family C member 9	target
Glyburide	Bile salt export pump	target
Glyburide	ATP-binding cassette sub-family A member 1	target
Glyburide	Cystic fibrosis transmembrane conductance regulator	target
Glyburide	Sulfonylurea receptor 1, Kir6.2	target
Glyburide	Cytochrome P450 2C9	enzyme
Glyburide	Canalicular multispecific organic anion transporter 2	transporter
Glyburide	Bile salt export pump	transporter
Glyburide	P-glycoprotein 1	transporter
Glyburide	Multidrug resistance-associated protein 1	transporter
Glyburide	Solute carrier family 15 member 1	transporter
Glyburide	Solute carrier organic anion transporter family member 1A2	transporter
Glyburide	Solute carrier family 15 member 2	transporter
Glyburide	Solute carrier family 22 member 6	transporter
Glyburide	Canalicular multispecific organic anion transporter 1	transporter
Glyburide	ATP-binding cassette sub-family G member 2	transporter
Glyburide	Solute carrier family 22 member 7	transporter
Glyburide	Solute carrier organic anion transporter family member 2B1	transporter
Glyburide	Cytochrome P450 2C19	enzyme
Glyburide	Cytochrome P450 3A4	enzyme
Glyburide	Serum albumin	carrier
Glyburide	Mitochondrial ATP-sensitive potassium channel	target
Glyburide	Carnitine O-palmitoyltransferase 1, liver isoform	target
Glyburide	Cytochrome P450 3A7	enzyme
Glyburide	Cytochrome P450 3A5	enzyme
Glyburide	Transient receptor potential cation channel subfamily M member 4	target
Ibuprofen	Prostaglandin G/H synthase 1	target
Ibuprofen	Prostaglandin G/H synthase 2	target
Ibuprofen	Cytochrome P450 2C9	enzyme
Ibuprofen	Serum albumin	carrier
Ibuprofen	Multidrug resistance-associated protein 4	transporter
Ibuprofen	Multidrug resistance-associated protein 1	transporter
Ibuprofen	Solute carrier organic anion transporter family member 1A2	transporter
Ibuprofen	Solute carrier family 22 member 6	transporter
Ibuprofen	Solute carrier family 22 member 8	transporter
Ibuprofen	Solute carrier family 22 member 11	transporter
Ibuprofen	Solute carrier organic anion transporter family member 2B1	transporter
Ibuprofen	P-glycoprotein 1	transporter
Ibuprofen	UDP-glucuronosyltransferase 1-3	enzyme
Ibuprofen	UDP-glucuronosyltransferase 1-9	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B4	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B7	enzyme
Ibuprofen	Cytochrome P450 2C8	enzyme
Ibuprofen	Cytochrome P450 2C19	enzyme
Ibuprofen	Apoptosis regulator Bcl-2	target
Ibuprofen	Thrombomodulin	target
Ibuprofen	Fatty acid-binding protein, intestinal	target
Ibuprofen	Peroxisome proliferator-activated receptor gamma	target
Ibuprofen	Cystic fibrosis transmembrane conductance regulator	target
Ibuprofen	Peroxisome proliferator-activated receptor alpha	target
Ibuprofen	Platelet glycoprotein Ib alpha chain	target
Ibuprofen	Protein S100-A7	target
Ibuprofen	Alpha-methylacyl-CoA racemase	enzyme
Ibuprofen	Cytochrome P450 3A4	enzyme
Benzylpenicillin	Solute carrier family 22 member 5	transporter
Benzylpenicillin	Solute carrier family 15 member 1	transporter
Benzylpenicillin	Solute carrier family 15 member 2	transporter
Benzylpenicillin	Solute carrier family 22 member 6	transporter
Benzylpenicillin	Solute carrier family 22 member 8	transporter
Benzylpenicillin	Solute carrier family 22 member 4	transporter
Benzylpenicillin	Solute carrier family 22 member 11	transporter
Benzylpenicillin	Solute carrier organic anion transporter family member 2B1	transporter
Benzylpenicillin	Solute carrier organic anion transporter family member 4A1	transporter
Benzylpenicillin	Solute carrier organic anion transporter family member 3A1	transporter
Benzylpenicillin	Solute carrier organic anion transporter family member 1B1	transporter
Benzylpenicillin	Penicillin-binding protein 3	target
Benzylpenicillin	Solute carrier family 22 member 8	target
Benzylpenicillin	Solute carrier family 15 member 1	target
Benzylpenicillin	Solute carrier family 15 member 2	target
Benzylpenicillin	Beta-lactamase TEM	enzyme
Benzylpenicillin	Serum albumin	carrier
Atorvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Atorvastatin	Cytochrome P450 3A4	enzyme
Atorvastatin	Dipeptidyl peptidase 4	target
Atorvastatin	Cytochrome P450 2D6	enzyme
Atorvastatin	Cytochrome P450 2C9	enzyme
Atorvastatin	Cytochrome P450 2C19	enzyme
Atorvastatin	Cytochrome P450 3A5	enzyme
Atorvastatin	Cytochrome P450 3A7	enzyme
Atorvastatin	P-glycoprotein 1	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1A2	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1B1	transporter
Atorvastatin	Multidrug resistance-associated protein 4	transporter
Atorvastatin	Multidrug resistance-associated protein 5	transporter
Atorvastatin	Multidrug resistance-associated protein 1	transporter
Atorvastatin	Cytochrome P450 2B6	enzyme
Atorvastatin	Cytochrome P450 2C8	enzyme
Atorvastatin	Aryl hydrocarbon receptor	target
Atorvastatin	Solute carrier organic anion transporter family member 2B1	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1B3	transporter
Atorvastatin	UDP-glucuronosyltransferase 1-1	enzyme
Atorvastatin	UDP-glucuronosyltransferase 1-3	enzyme
Atorvastatin	Canalicular multispecific organic anion transporter 1	transporter
Atorvastatin	Bile salt export pump	transporter
Atorvastatin	Serum albumin	carrier
Atorvastatin	Histone deacetylase 2	target
Atorvastatin	Nuclear receptor subfamily 1 group I member 3	target
Iloprost	Prostacyclin receptor	target
Iloprost	Tissue-type plasminogen activator	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Iloprost	Solute carrier organic anion transporter family member 2B1	transporter
Iloprost	Solute carrier organic anion transporter family member 2A1	transporter
Iloprost	Solute carrier organic anion transporter family member 3A1	transporter
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Iloprost	Prostaglandin E2 receptor EP1 subtype	target
Iloprost	Prostaglandin D2 receptor 2	target
Iloprost	Serum albumin	carrier
Tolbutamide	ATP-sensitive inward rectifier potassium channel 1	target
Tolbutamide	Cytochrome P450 2C19	enzyme
Tolbutamide	Cytochrome P450 2C9	enzyme
Tolbutamide	Cytochrome P450 2C8	enzyme
Tolbutamide	ATP-binding cassette sub-family C member 8	target
Tolbutamide	Solute carrier family 15 member 1	transporter
Tolbutamide	Solute carrier organic anion transporter family member 1A2	transporter
Tolbutamide	Solute carrier family 15 member 2	transporter
Tolbutamide	Solute carrier family 22 member 6	transporter
Tolbutamide	Solute carrier organic anion transporter family member 2B1	transporter
Tolbutamide	Cytochrome P450 2C18	enzyme
Tolbutamide	Serum albumin	carrier
Prasterone	Cytochrome P450 3A7	enzyme
Prasterone	Peroxisome proliferator-activated receptor alpha	target
Prasterone	Estrogen receptor alpha	target
Prasterone	Sigma non-opioid intracellular receptor 1	target
Prasterone	Estrogen receptor beta	target
Prasterone	Nuclear receptor subfamily 1 group I member 2	target
Prasterone	Nuclear receptor subfamily 1 group I member 3	target
Prasterone	GABA(A) Receptor	target
Prasterone	NMDA receptor	target
Prasterone	Androgen receptor	target
Prasterone	Estradiol 17-beta-dehydrogenase 1	enzyme
Prasterone	Bile salt sulfotransferase	enzyme
Prasterone	Sulfotransferase family cytosolic 2B member 1	enzyme
Prasterone	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	enzyme
Prasterone	Cholesterol oxidase	enzyme
Prasterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Prasterone	Solute carrier organic anion transporter family member 1B3	transporter
Prasterone	Solute carrier organic anion transporter family member 2B1	transporter
Prasterone	Solute carrier organic anion transporter family member 1B1	transporter
Prasterone	Solute carrier organic anion transporter family member 1A2	transporter
Prasterone	Multidrug resistance-associated protein 1	transporter
Prasterone	ATP-binding cassette sub-family G member 2	transporter
Prasterone	Multidrug resistance-associated protein 4	transporter
Acetic acid	Solute carrier organic anion transporter family member 2B1	transporter
Acetic acid	Monocarboxylate transporter 1	transporter
Taurocholic acid	Bile salt-activated lipase	target
Taurocholic acid	Gastrotropin	target
Taurocholic acid	Bile salt export pump	transporter
Taurocholic acid	Multidrug resistance-associated protein 1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1A2	transporter
Taurocholic acid	Ileal sodium/bile acid cotransporter	transporter
Taurocholic acid	Canalicular multispecific organic anion transporter 1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1B1	transporter
Taurocholic acid	Canalicular multispecific organic anion transporter 2	transporter
Taurocholic acid	Multidrug resistance-associated protein 4	transporter
Taurocholic acid	P-glycoprotein 1	transporter
Taurocholic acid	Solute carrier family 22 member 6	transporter
Taurocholic acid	Multidrug resistance-associated protein 7	transporter
Taurocholic acid	Solute carrier family 22 member 8	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 4A1	transporter
Taurocholic acid	ATP-binding cassette sub-family C member 11	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1C1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 3A1	transporter
Taurocholic acid	ATP-binding cassette sub-family G member 2	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 2B1	transporter
Taurocholic acid	Monocarboxylate transporter 1	transporter
Taurocholic acid	Sodium/bile acid cotransporter	transporter
Taurocholic acid	Organic solute transporter subunit alpha	transporter
Taurocholic acid	Organic solute transporter subunit beta	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1B3	transporter
Taurocholic acid	Cystine/glutamate transporter	transporter
Taurocholic acid	Bile acid receptor	target
Lactic acid	Bifunctional protein PutA	target
Lactic acid	NimA-related protein	target
Lactic acid	Monocarboxylate transporter 2	transporter
Lactic acid	Solute carrier organic anion transporter family member 2B1	transporter
Lactic acid	Monocarboxylate transporter 1	transporter
Lactic acid	Monocarboxylate transporter 10	transporter
Lactic acid	Solute carrier organic anion transporter family member 2A1	transporter
Lactic acid	Monocarboxylate transporter 4	transporter
Simeprevir	NS3 protease	target
Simeprevir	Serum albumin	carrier
Simeprevir	Cytochrome P450 1A2	enzyme
Simeprevir	P-glycoprotein 1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B3	transporter
Simeprevir	Cytochrome P450 3A4	enzyme
Simeprevir	Canalicular multispecific organic anion transporter 1	transporter
Simeprevir	ATP-binding cassette sub-family G member 2	transporter
Simeprevir	Solute carrier organic anion transporter family member 2B1	transporter
Simeprevir	Sodium/bile acid cotransporter	transporter
Simeprevir	Bile salt export pump	transporter
Simeprevir	NS3/4A protein	target
Pitavastatin	Solute carrier organic anion transporter family member 1B1	transporter
Pitavastatin	Solute carrier organic anion transporter family member 1B3	transporter
Pitavastatin	UDP-glucuronosyltransferase 2B7	enzyme
Pitavastatin	UDP-glucuronosyltransferase 1-3	enzyme
Pitavastatin	Cytochrome P450 2C9	enzyme
Pitavastatin	Cytochrome P450 2C8	enzyme
Pitavastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pitavastatin	Solute carrier organic anion transporter family member 2B1	transporter
Pitavastatin	Sodium/bile acid cotransporter	transporter
Pitavastatin	ATP-binding cassette sub-family G member 2	transporter
Pitavastatin	P-glycoprotein 1	transporter
Pitavastatin	Canalicular multispecific organic anion transporter 1	transporter
Pitavastatin	Serum albumin	carrier
Pitavastatin	Alpha-1-acid glycoprotein 1	carrier
Pitavastatin	Bile salt export pump	transporter
Pitavastatin	Integrin alpha-L	target
Asunaprevir	Genome polyprotein	target
Asunaprevir	Cytochrome P450 3A4	enzyme
Asunaprevir	Cytochrome P450 3A5	enzyme
Asunaprevir	Cytochrome P450 2A6	enzyme
Asunaprevir	Cytochrome P450 2B6	enzyme
Asunaprevir	Cytochrome P450 2C9	enzyme
Asunaprevir	Cytochrome P450 2C19	enzyme
Asunaprevir	Cytochrome P450 2D6	enzyme
Asunaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Asunaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Asunaprevir	Solute carrier organic anion transporter family member 2B1	transporter
Asunaprevir	P-glycoprotein 1	transporter
Lifitegrast	Integrin alpha-L	target
Lifitegrast	Cytochrome P450 2C9	enzyme
Lifitegrast	Solute carrier organic anion transporter family member 1A2	transporter
Lifitegrast	Solute carrier organic anion transporter family member 2B1	transporter
Opicapone	Cytochrome P450 2C19	enzyme
Opicapone	Cytochrome P450 2C8	enzyme
Opicapone	Catechol O-methyltransferase	target
Opicapone	Solute carrier organic anion transporter family member 1B1	transporter
Opicapone	P-glycoprotein 1	transporter
Opicapone	ATP-binding cassette sub-family G member 2	transporter
Opicapone	Solute carrier organic anion transporter family member 1B3	transporter
Opicapone	Solute carrier organic anion transporter family member 2B1	transporter
Opicapone	Cytochrome P450 2C9	enzyme
Opicapone	Cytochrome P450 1A2	enzyme
Opicapone	Cytochrome P450 2B6	enzyme
Latanoprostene bunod	Prostaglandin F2-alpha receptor	target
Latanoprostene bunod	Solute carrier organic anion transporter family member 2B1	transporter
Mesalazine	Prostaglandin G/H synthase 1	target
Mesalazine	Prostaglandin G/H synthase 2	target
Mesalazine	Peroxisome proliferator-activated receptor gamma	target
Mesalazine	Inhibitor of nuclear factor kappa-B kinase subunit alpha	target
Mesalazine	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Mesalazine	Arachidonate 5-lipoxygenase	target
Mesalazine	Arylamine N-acetyltransferase 1	enzyme
Mesalazine	Solute carrier organic anion transporter family member 1B1	transporter
Mesalazine	Solute carrier organic anion transporter family member 1B3	transporter
Mesalazine	Solute carrier organic anion transporter family member 2B1	transporter
Mesalazine	Nitric oxide synthase, inducible	target
Elacestrant	Estrogen receptor alpha	target
Elacestrant	Cytochrome P450 3A4	enzyme
Elacestrant	Cytochrome P450 2A6	enzyme
Elacestrant	Cytochrome P450 2C9	enzyme
Elacestrant	Solute carrier organic anion transporter family member 2B1	transporter
Elacestrant	P-glycoprotein 1	transporter
Elacestrant	ATP-binding cassette sub-family G member 2	transporter
Alprostadil	Prostaglandin E2 receptor EP2 subtype	target
Alprostadil	Prostaglandin E2 receptor EP1 subtype	target
Alprostadil	Multidrug resistance-associated protein 5	transporter
Alprostadil	Solute carrier organic anion transporter family member 2B1	transporter
Alprostadil	Solute carrier organic anion transporter family member 3A1	transporter
Alprostadil	Multidrug resistance-associated protein 4	transporter
Alprostadil	Solute carrier organic anion transporter family member 2A1	transporter
Alprostadil	Prostaglandin D2 receptor 2	target
Alprostadil	Solute carrier family 22 member 6	transporter
Alprostadil	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	enzyme
Alprostadil	Serum albumin	carrier
Alprostadil	Prostaglandin E2 receptor EP3 subtype	target
Alprostadil	Prostaglandin E2 receptor EP4 subtype	target