Hepatotoxic Agents, Most DILI Concern

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DBCAT006071Pharmacologic class

Drugs classified as Most-DILI-Concern in the FDA DILIrank 2.0 dataset. These agents carry hepatotoxicity in the most serious sections of their FDA labeling, such as boxed warnings, together with a causal association with clinically significant... A DrugBank category of 210 drugs. 187 of them are approved.

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Hepatotoxic Agents
Drugs

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What you can answer from here — as of July 02, 2026

210DrugsEach linked to its full drug card
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474Drug targetsEvery drug–target pair in the class, with bond type
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67,859Marketed productsAcross the regions we cover, with dosage forms and routes
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37Routes of administrationHow the drugs in this class are given
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1ReferenceSupporting the category definition
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Which targets do Hepatotoxic Agents, Most DILI Concern share, and which companies have late-stage candidates in this class?

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