Sulfonamides
- Name
- Sulfonamides
- Accession Number
- DBCAT000514 (DBCAT002222, DBCAT002263, DBCAT002527, DBCAT002687)
- Description
A group of compounds that contain the structure SO2NH2.
- ATC Classification
- Drugs
Drug Drug Description 4-(2-AMINOETHYL)BENZENESULFONAMIDE Not Available 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available ABT-639 ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain). ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Acetazolamide A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. Acetohexamide Used in the management of diabetes mellitus type 2 (adult-onset). Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Asnuciclib Asnuciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Asnuciclib is a cyclin dependant kinase inhibitor. Asnuciclib has a monoisotopic molecular... Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Batabulin Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients). Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Benzolamide Not Available Benzthiazide For the treatment of high blood pressure and management of edema. Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Buthiazide A diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases. Carbutamide Not Annotated Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Chlorothiazide A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Chlorpropamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Clofenamide Not Annotated Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Clorexolone Not Annotated Clorsulon Not Annotated Cyclopenthiazide Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... Cyclothiazide Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either... Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Deracoxib Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to... Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Dubermatinib Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL). Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Fasudil Fasudil has been investigated in Carotid Stenosis. Fedratinib Fedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis. Fenquizone Not Annotated Flumethiazide Flumethiazide is a small molecule drug. Flumethiazide has a monoisotopic molecular weight of 328.98 Da. Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Gefapixant A P2X3 receptor antagonist that reduces the cough reflex in patients with refractory or unexplained chronic cough. Gliclazide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Glybuzole Glybuzole is a small molecule drug. Glybuzole has a monoisotopic molecular weight of 297.06 Da. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Grapiprant The effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved... GSK-2981278 GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis). Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Hydroxyfasudil Not Available Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Indisulam Investigated for use/treatment in lung cancer. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Mebutizide Not Annotated Mefruside Not Annotated Methazolamide A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. Methyclothiazide A diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy. Meticrane Meticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure . Metolazone A thiazide-like diuretic used to treat hypertension. Mitapivat A pyruvate kinase activator used to treat anemia with thalassemia and hemolytic anemia in adults with pyruvate kinase (PK) deficiency. Omidenepag isopropyl An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure. Omipalisib Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis. Oveporexton An oral orexin receptor 2 (OX2R)-selective agonist indicated for narcolepsy type 1 in adults, restoring deficient orexin signaling to promote wakefulness and reduce cataplexy and other REM-sleep-related symptoms. p-Toluenesulfonamide Not Available PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Piretanide A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Quinethazone Used to treat hypertension. Risotilide Risotilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Risotilide is a sematilide derivative class III antiarrhythmic. Risotilide has a monoisotopic... Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . Setrobuvir Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Sonepiprazole Sonepiprazole is a small molecule drug. The usage of the INN stem '-prazole' in the name indicates that Sonepiprazole is a benzimidazole derivative antiulcer medication. Sonepiprazole has a monoisotopic molecular... Succinylsulfathiazole Not Annotated Sulfacarbamide Sulfacarbamide is a small molecule drug. Sulfacarbamide has a monoisotopic molecular weight of 215.04 Da. Sulfacetamide A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris. Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaclomide Sulfaclomide is a small molecule drug. Sulfaclomide has a monoisotopic molecular weight of 312.04 Da. Sulfaclozine Sulfaclozine is a small molecule drug. Sulfaclozine has a monoisotopic molecular weight of 284.01 Da. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sulfadicramide Not Annotated Sulfadimethoxine For use in the treatment of infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Sulfaethoxypyridazine Not Annotated Sulfaguanidine Sulfaguanidine is a sulfonamide antibiotic with antimicrobial and antibacterial activities. Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Sulfamazone Not Annotated Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Sulfametomidine Not Annotated Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Sulfamoxole For the treatment of bacterial infection. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfanitran Not Annotated Sulfaperin Not Annotated Sulfaphenazole For the treatment bacterial infections. Sulfaproxyline Sulfaproxyline is a small molecule drug. Sulfaproxyline has a monoisotopic molecular weight of 334.1 Da. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Sulfasalazine A salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Sulfasymazine Sulfasymazine is a small molecule drug. Sulfasymazine has a monoisotopic molecular weight of 307.11 Da. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfathiourea Not Annotated Sulfatolamide Not Annotated Sulfatroxazole Sulfatroxazole is a small molecule drug. Sulfatroxazole has a monoisotopic molecular weight of 267.07 Da. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Sulthiame A carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Susalimod Susalimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Susalimod is a immunomodulator, both stimulant/suppressive and stimulant. Susalimod has a monoisotopic... Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Tilmacoxib Tilmacoxib is a small molecule drug. The usage of the INN stem '-coxib' in the name indicates that Tilmacoxib is a selective cyclo-oxygenase inhibitor. Tilmacoxib has a monoisotopic molecular weight... Tinlorafenib Tinlorafenib (PF-07284890) is a potent, selective, highly brain-penetrant, small-molecule inhibitor of BRAF V600 mutations. TO-901317 TO-901317 is an LXRalpha and LXRbeta agonist. Tolazamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Tosifen Tosifen is a small molecule drug. Tosifen has a monoisotopic molecular weight of 332.12 Da. Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. Trametinib A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer. Trichlormethiazide Used in the treatment of oedema (including that associated with heart failure) and hypertension. TTI-101 Not Annotated Udenafil A PDE5 inhibitor used to treat erectile dysfunction. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. VLX-1005 Not Annotated Xipamide A diuretic indicated in the treatment of edema. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures.