Leishmaniasis (DBCOND0013913)

Identifiers

Synonyms
Leishmaniasis, unspecified / Leishmania infections / Leishmaniasis (disorder) / Leishmaniasis NOS

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amphotericin B
An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
Sodium stibogluconate
For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment...
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00344188
Diagnosis and Treatment of Leishmania InfectionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02429505
Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient RegistryNot AvailableNot Availablewithdrawn
NCT02656797
Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasistreatment2completed
NCT03294161
Fourth-generation Immucillin Derivative DI4G Associated Therapy in Cutaneous Leishmaniasistreatment2completed
NCT03993093
Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART CentreNo drug interventionsNot AvailableNot Availablecompleted
NCT06307171
Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential BiomarkersNo drug interventionsdiagnosticNot Availablerecruiting
NCT01300975
Intralesional Antimony for Bolivian Cutaneous Leishmaniasistreatment2completed
NCT04512742
A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand FliesNo drug interventionsotherNot Availablecompleted
NCT00401349
Expression of Mif Alleles in Individuals With LeishmaniasisNo drug interventionsNot AvailableNot Availablecompleted
NCT00657618
Use of Sodium Stibogluconate as a Treatment for Leishmaniasistreatment1 / 2completed
NCT03874234
Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy SubjectsNo drug interventionstreatment1terminated
NCT03641339
Defining Skin Immunity of a Bite of Key Insect Vectors in HumansNo drug interventionsbasic_scienceNot Availablecompleted
NCT00401557
Mechanisms Relating to the Distinct in Vitro Susceptibility of Human Macrophages to L. Viannia InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01377974
Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasistreatment2completed
NCT01437020
SCH708980 With and Without AmBisome for Visceral Leishmaniasistreatment1 / 2withdrawn
NCT00373776
Miltefosine for Mucosal Leishmaniasistreatment1 / 2completed
NCT06124144
Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adultstreatment1terminated
NCT00662012
Sodium Stibogluconate Treatment of Leishmaniasistreatment2completed
NCT00401297
Th1/Th2 Polarization and Linkage to L. Viannia Infection OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT02530697
The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Braziltreatment2active_not_recruiting
NCT05449717
Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South SudanNo drug interventionsNot AvailableNot Availablerecruiting
NCT04504435
Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy ParticipantsNo drug interventionstreatment1completed
NCT03009422
Fractional CO2 Laser With Topical Pentostam Treatment for Cutaneous Leishmaniasis.treatmentNot Availableunknown_status
NCT01751048
LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccineprevention1completed
NCT03784248
Mediterranean Visceral Leishmaniasis With Leishmania InfantumNo drug interventionsNot AvailableNot Availablerecruiting
NCT01484548
Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteersprevention1completed
NCT00373568
Miltefosine (Long Course) for Bolivian Mucosal Leishmaniasistreatment1 / 2completed
NCT00001169
Clinical Investigation of Infections Due to Leishmanial ParasitesNo drug interventionsNot AvailableNot Availablecompleted
NCT00004755
Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Braziltreatment2completed