Subfoveal Choroidal Neovascularization (CNV) (DBCOND0037885)

Identifiers

Synonyms
Neovascularization, Choroidal / Choroidal Neovascularization / Subfoveal Choroidal Neovascularization / Choroidal Neovascularization (CNV) / Choroidal neovascularisation

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Verteporfin
A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06125977
Impact of Non-Exudative Type 1 MNV on AMD ProgressionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03038880
Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degenerationtreatment2completed
NCT01162746
Comparison of Ranibizumab Monotherapy and Ranibizumab Combination Therapies in Recurrent or Persistent Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT00260403
TTT Versus PDT for Treatment of Choroidal Neovascularization in Age-Related Macular DegenerationNo drug interventionstreatment2 / 3unknown_status
NCT00417703
Intraocular Pressure Immediately Following Intravitreous Injection of RanibizumabNo drug interventionsNot AvailableNot Availablecompleted
NCT01570790
Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degenerationtreatment1 / 2completed
NCT00331864
SUSTAIN - Study of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degenerationtreatment3completed
NCT00492284
Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)treatment2completed
NCT04488887
OCTA Metrics Repeatability and Reproducibility in Different DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT02260687
Special Drug Use Investigation of EYLEA for Myopic Choroidal NeovascularizationNot AvailableNot Availablecompleted
NCT01628354
Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degenerationtreatment4completed
NCT00395551
Safety Study of Ranibizumab Eye Injections to Treat Choroidal Neovascularization That Was Caused Other Than by Age-Related Macular Degeneration.treatment1completed
NCT02015351
Intravitreal Bevacizumab for the Treatment of CNV in VKH Disease - A Prospective StudytreatmentNot Availablecompleted
NCT00436553
Efficacy/Safety of Verteporfin Photodynamic Therapy and Ranibizumab Compared With Ranibizumab in Patients With Subfoveal Choroidal Neovascularizationtreatment3completed
NCT00426998
Combination Bevacizumab and Verteporfin (Two Different Sequences of Treatment)in Neovascular AMDtreatment2completed
NCT00570193
Photodynamic and Pharmacologic Treatment of CNVtreatment1 / 2completed
NCT04782271
Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye DropsNo drug interventionstreatment1completed
NCT03042871
Dosing Strategy of Intravitreal Ranibizumab for Pathological Myopia Choroidal Neovascularizationtreatment4completed
NCT01880788
Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT04075188
Treatment of Polypoidal Choroidal Vasculopathy in PachychoroidtreatmentNot Availablecompleted
NCT00008515
Fluocinolone Implant to Treat Macular Degenerationtreatment1completed
NCT02308215
Retinal Therapy Guided by 3D OCT Image AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT00102115
Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Diseasetreatment1terminated
NCT01256632
Evaluation of the Effect of Vitreous Composition Determined by Ultrasound and Optical Coherence Tomography (OCT) on Ranibizumab TherapyNot AvailableNot Availablecompleted
NCT01136252
Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT00251459
A Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)treatment3completed
NCT05494775
Effect of Corona Virus on Intravitreal InjectionsNo drug interventionstreatmentNot Availableunknown_status
NCT01531842
A Research Study to Evaluate the Effects of Repeated Intravitreal Injections on Bacteria Around the EyeNo drug interventionssupportive_careNot Availableunknown_status
NCT01666236
Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal VasculopathyNo drug interventionstreatment4withdrawn
NCT00021736
Phase II/III Study of Anti-VEGF in Neovascular AMDtreatment2 / 3completed
NCT00407719
Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD)treatment1completed
NCT03024424
Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMDNo drug interventionspreventionNot Availablecompleted
NCT01908816
An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases.treatment3completed
NCT00370786
Effect of Intravitreal Bevacizumab on Non -Age-Related Macular Degeneration (AMD) Related Choroidal Neovascularization (CNV)treatment3completed
NCT01948830
Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMDsupportive_care3completed
NCT00509548
Open-Label, Pilot Study of TG100801 in Patients With Choroidal Neovascularization Due to AMDtreatment2terminated
NCT00272766
Macugen for HistoplasmosistreatmentNot Availableterminated
NCT00599820
Use of Intravitreal Bevacizumab in Eyes With Choroidal Neovascularization Secondary to Angioid Streakstreatment3terminated
NCT02307682
Efficacy and Safety of RTH258 Versus Aflibercept - Study 1treatment3completed
NCT03452527
Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)treatment2terminated
NCT02857894
Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated)No drug interventionsNot AvailableNot Availableterminated
NCT00568191
Stratus Versus Cirrus OCT in AMDNo drug interventionsNot AvailableNot Availableunknown_status
NCT00712491
Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degenerationtreatment1 / 2terminated
NCT01256580
Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMDtreatmentNot Availablewithdrawn
NCT02358889
Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT00406744
Efficacy of Retreatments With Intravitreal Bevacizumabtreatment3terminated
NCT01298440
Bevacizumab Effect on Blood VelocityNo drug interventionsNot AvailableNot Availablecompleted
NCT00417846
Age-related Macular Degeneration: Detection of Onset of New Choroidal Neovascularization (AMD DOC Study)No drug interventionsNot AvailableNot Availablecompleted
NCT00813514
Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)?No drug interventionsdiagnosticNot Availablewithdrawn
NCT03409250
SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopiatreatment4completed
NCT00967850
Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High Myopiatreatment3completed
NCT00855608
Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Studytreatment1unknown_status
NCT04439708
Biomarkers and Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availableunknown_status
NCT05662943
Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCVNot AvailableNot Availablecompleted
NCT02484690
A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)treatment2completed
NCT02486484
Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injectiontreatment2unknown_status
NCT03838679
Imaging of the Angiofibrotic Switch in Neovascular AMDNo drug interventionsNot AvailableNot Availableunknown_status
NCT00100087
Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy SystemNo drug interventionstreatment1 / 2unknown_status
NCT00417833
Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)TreatmentNot Available2 / 3terminated
NCT00304954
Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degenerationtreatment2completed
NCT02821247
Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in GreeceNot AvailableNot Availablecompleted
NCT02434328
Efficacy and Safety of RTH258 Versus Aflibercept - Study 2treatment3completed
NCT00775411
Safety and Efficacy of a New Therapy as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) in Subjects With Wet Age-Related Macular Degeneration (AMD)treatment2completed
NCT00604071
Sensitivity of the Home Macular Perimeter (HMP)No drug interventionsNot AvailableNot Availablecompleted
NCT00470678
EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)treatment3completed
NCT01336907
Comparison Between Home Macular Perimeter and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)No drug interventionsNot AvailableNot Availablewithdrawn
NCT03105609
Enhancing the Lucentis (Ranibizumab) Management of Choroidal Neovascular Membranes With Hyperspectral ImagingNo drug interventionsNot AvailableNot Availableterminated
NCT01021956
Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMDNo drug interventionstreatment2terminated
NCT00403156
Imatinib Mesylate Combined With Intravitreal Ranibizumab in the Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degenerationtreatment1withdrawn
NCT00001615
Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular DegenerationNo drug interventionstreatment1completed
NCT00766337
Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degenerationtreatment2terminated
NCT03793400
Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth FactorNot AvailableNot Availablecompleted
NCT00473642
Reduced Fluence Photodynamic Therapy (PDT) With Visudyne in Combination With Lucentis for Age-Related Macular Degenerationtreatment4completed
NCT01445899
PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME)treatment2completed
NCT04455399
Time Efficiency Comparison of Two IntraVitreal Injection TechniquesNo drug interventionstreatmentNot Availablecompleted
NCT06243406
Study on the Biomarkers of Anti-VEGF Treatment for Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00511706
Safety and Efficacy of a New Treatment as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment in Patients With Age-Related Macular Degeneration (AMD)treatment2completed
NCT01423149
Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopiatreatment2completed
NCT02934841
Conbercept in Choroidal Neovascularization Secondary to Uveitistreatment2unknown_status
NCT00433017
Verteporfin Photodynamic Therapy Administered in Conjunction With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)treatment2 / 3terminated
NCT00000158
Macular Photocoagulation Study (MPS)No drug interventionstreatment3unknown_status
NCT01025063
Use of Spectral OCT in Combination TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00305630
Neovascular Age Related Macular Degeneration (AMD), Periocular Corticosteroids, and Photodynamic Therapy (PDT)treatment2 / 3completed
NCT00510965
Ranibizumab to Treat Choroidal Neovascularization (CNV) in Patients With Pseudoxanthoma Elasticum (PXE)treatment2completed
NCT00533520
Evaluation of Dosing Interval of Higher Doses of Ranibizumabtreatment4completed
NCT01578720
Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrometreatment1completed
NCT05055973
OCTA Insights in CNVM, Morphological Characteristics and Correlation With Structural OCT.No drug interventionsNot AvailableNot Availableunknown_status
NCT01334294
Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00429962
Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNVtreatment3completed
NCT00242580
A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanibtreatment3completed
NCT03393767
Time Course of Activity Signs at SD-OCT High Frequency Intravitreal Ranibizumab Treatment in CNV Due to AMDtreatment4completed
NCT00363168
Ranibizumab in Hemorrhagic Choroidal Neovascularization Trialtreatment1completed
NCT00729846
Bevacizumab in Combination With Visudyne Photodynamic Therapy (PDT)treatment2completed
NCT01175395
20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD)treatment1 / 2completed
NCT00363714
A Dose Escalation Trial of an Intravitreal Injection of Sirna-027 in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)treatment1 / 2completed
NCT00406250
Intravitreal Bevacizumab in Agioid Streakstreatment1completed
NCT02599064
Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMDNo drug interventionstreatment1 / 2unknown_status
NCT01122511
Safety and Efficacy of Dexamethasone as Adjunctive Therapy to Ranibizumab in Subjects With Choroidal Neovascularization and Age-Related Macular Degenerationtreatment2terminated
NCT00930189
Comparative Study With Photodynamic Therapy And Triamcinolone Versus Photodynamic Therapy, Triamcinolone And Ranibizumab In Patients With Subfoveal Choroidal Neovascularizationtreatment2 / 3withdrawn
NCT00327470
An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMDtreatment4terminated
NCT00902785
A Study Of Early Markers Of Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availableterminated
NCT01840410
Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.treatment3completed
NCT00504959
Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment4completed