Otitis Media (OM) (DBCOND0059550)

Identifiers

Synonyms
Otitis Media / Otitis media, unspecified / Otitis media, unspecified, unspecified ear / Otitis media (disorder) / Middle ear infection / Unspecified otitis media / Otitis media NOS / Middle ear inflammation / Catarrh of middle ear

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Antipyrine
An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
Carbocisteine
A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
Cefpodoxime
A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
Cephalexin
A first generation cephalosporin used to treat certain susceptible bacterial infections.
Ciprofloxacin
A second generation fluoroquinolone used to treat various susceptible bacterial infections.
Clarithromycin
A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
Clavulanic acid
A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
Fludrocortisone
A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
Midecamycin
A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.
Naphazoline
A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
Sitafloxacin
A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01694329
Impact of Introduction of PHiD-CV for Nunavik Children, Quebec, CanadaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01735084
Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Lifeprevention4completed
NCT01496287
Tympanostomy Tube Placement in Children in the Office (Inova Study)No drug interventionstreatmentNot Availablecompleted
NCT05741333
In-Office Clinical Study of the Solo+ TTDNo drug interventionstreatmentNot Availablerecruiting
NCT04016051
Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infectionstreatment3completed
NCT04219553
Antimicrobial Stewardship in Community PharmacyNo drug interventionsotherNot Availablecompleted
NCT01046877
Singapore Tympanostomy Tube Delivery System StudyNo drug interventionstreatmentNot Availablecompleted
NCT00001605
Vaccination for Middle Ear InfectionNo drug interventionstreatment1completed
NCT05127161
Broad Implementation of Outpatient StewardshipNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT00174811
Comparative Study to Evaluate the Efficacy and Safety of Telithromycin Given Once Daily Versus Cefuroxime Axetil Given Twice Daily in Children With Middle Ear Infectionstreatment3terminated
NCT00581711
Improving Otitis Media Care With Clinical Decision SupportNo drug interventionstreatment3completed
NCT01324271
inVENT-In-Office StudyNo drug interventionstreatmentNot Availablecompleted
NCT03890107
Clinical Evaluation of the OtoSightNo drug interventionsNot AvailableNot Availablecompleted
NCT04743609
RSV Burden in Outpatient SettingsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01775709
Evaluation of a New Biocompatible Pressure Equalizing TubeNo drug interventionspreventionNot Availablewithdrawn
NCT00847756
Host-pathogen Interaction in Otitis MediaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05641285
Diagnostic Utility of Otosight Middle Ear ScopeNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04600752
Study to Evaluate the Safety and Clinical Efficacy of Augmentin® Extra Strength-600 in Children With Acute Otitis Media in Indiatreatment4completed
NCT00360100
Zmax Pediatric Vs Adult Concentration For The Treatment Of Acute Otitis Mediatreatment3completed
NCT00250900
Wait and See Antibiotic Prescription for Acute Otitis Media: A Randomized Controlled TrialNo drug interventionstreatmentNot Availablecompleted
NCT02600559
Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubestreatment3completed
NCT01174849
Pneumococcal Vaccines Early and in Combinationprevention4completed
NCT01437436
The Effect of Obesity on Ventilation Tube InsertionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00422136
Genetics of Middle Ear DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06260618
Effect of Chitodex Gel in Tympanoplasty SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT00378417
Efficacy Trial of Two Pneumococcal Conjugate Vaccines (PncCRM and PncOMPC) for Prevention of Acute Otitis Media Due to Vaccine Serotypesprevention3completed
NCT04148417
Clinical Study of the Solo+ Tympanostomy Tube DeviceNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00768534
Study Evaluating Microbiological Analysis of Spontaneous Draining Acute Otitis MediaNo drug interventionsNot AvailableNot Availablecompleted
NCT01199016
Effect of Prevnar 13 on Ear Infections in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT02592096
Pazufloxacin Mesilate Ear Drops Clinical Trial Protocoltreatment1unknown_status
NCT01588535
Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis Mediasupportive_care2completed
NCT00000363
Acute Otitis Media: Adjuvant Therapy to Improve OutcomeNo drug interventionstreatment3completed
NCT02788422
Video Discharge Instructions for Acute Otitis MediaNo drug interventionstreatmentNot Availablecompleted
NCT02979626
Evaluation of Moderate to Severe Influenza Outcomes in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT00617682
Maternal Immunization To Prevent Infant Otitis MediaNo drug interventionsprevention1 / 2completed
NCT01535131
Furlow Palatoplasty With Tensor TenopexyNo drug interventionstreatmentNot Availablecompleted
NCT00044473
A Study of the Effectiness and Safety of Levofloxacin in Treating Children With a Rapid and Severe Onset of Infection and Inflammation of the Middle Ear That is Difficult to Treattreatment3completed
NCT00162994
Prevention Recurrent Otitis Media in the Young ChildrenNo drug interventionspreventionNot Availableunknown_status
NCT03503591
Study of the Hummingbird TTS™ Tympanostomy Tube SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT00248391
The Influence of Feeding Position on Pulmonary Morbidity in Young ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT01619462
Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Childrentreatment3unknown_status
NCT00419380
Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)treatment4completed
NCT00365092
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11No drug interventionstreatmentNot Availablecompleted
NCT02150044
Acclarent Tympanostomy Tube Delivery System for the Treatment of Patients Requiring Tympanostomy Tube InsertionNo drug interventionstreatmentNot Availablecompleted
NCT00219401
Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New GuineaNo drug interventionsprevention2completed
NCT00689468
Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis MediaNo drug interventionspreventionNot Availablecompleted
NCT05353569
Coherent Optical Detection of Middle Ear DiseaseNo drug interventionsdiagnosticNot Availablerecruiting
NCT01339546
National Trends in Otitis Media in Children Under 5 Years of AgeNo drug interventionsNot AvailableNot Availablecompleted
NCT01003210
Homeopathic Ear Drops for Otitis Media Studysupportive_careNot Availablecompleted
NCT02972281
Systematic Search for Primary Immunodeficiency in Adults With InfectionsNo drug interventionsdiagnosticNot Availableterminated
NCT03864055
Otogenic CSVT Retrospective Case Series and Associated ThrombophiliaNo drug interventionsNot AvailableNot Availablecompleted
NCT01908764
Pharmacokinetic Study of AL-60371 Otic Suspension in Pediatric Subjects Following Tympanostomy Tube Surgerybasic_science1withdrawn
NCT02452164
Family MobilePhone Otoscopy in Diagnostics of Otitis MediaNo drug interventionsdiagnosticNot Availablecompleted
NCT04447521
Surveillance of Non-invasive Streptococcus Pneumoniae Infections in BelgiumNo drug interventionsNot AvailableNot Availablerecruiting
NCT00781521
Safety and Efficacy of Floxin Otic Solution in the Treatment of Acute Otitis Media in Childrentreatment3completed
NCT02165384
Hummingbird TTS Ear Tube Delivery StudyNo drug interventionstreatmentNot Availablecompleted
NCT02742753
Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT00051753
Levofloxacin In The Treatment Of Children With Recurrent And/or Persistent Acute Otitis Mediatreatment3completed
NCT02817347
A Clinical Trial of YH1177 in Patients With Otitis Media and Otorrheatreatment1 / 2terminated
NCT00195611
Study of Streptococcus Pneumoniae in Nose and Throats of Infants With Acute Otitis MediaNo drug interventionsNot AvailableNot Availablecompleted
NCT05915078
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02957578
Clinical Study of Solo Tympanostomy Tube Device (TTD)No drug interventionstreatmentNot Availableunknown_status
NCT02490332
The Effects of Ventilation Tubes - The SIUTIT TrialNo drug interventionspreventionNot Availableterminated
NCT00457600
ParentLink: Better and Safer Emergency Care for ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT00393159
The Influence of The Ear Popper on Serous Otitis Media and on the Accompanying Conductive Hearing Loss in ChildrenNo drug interventionstreatment4unknown_status
NCT00276042
A Trial to Evaluate Faropenem Medoxomil in the Treatment of Acute Otitis Mediatreatment2completed
NCT02653742
Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Childrentreatment4unknown_status
NCT00539149
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Childrenprevention4completed
NCT05429541
Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia.No drug interventionsNot AvailableNot Availablerecruiting
NCT00638534
Japanese Study Evaluating the Effects of Telithromycin in Children With Acute Otitis Mediatreatment3completed
NCT02616458
The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income PopulationNo drug interventionspreventionNot Availablecompleted
NCT00778063
Study Using Dexmedetomidine to Decreases Emergence Delirium in Pediatric PatientspreventionNot Availableterminated
NCT00956748
N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Mediatreatment4withdrawn
NCT01244126
Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomytreatment4completed
NCT00010465
Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in ChildrenNo drug interventionstreatment2completed
NCT03655665
Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Presentother4recruiting
NCT02592382
Nasal Xylitol in the Prevention of Otitis MediaNo drug interventionspreventionNot Availablecompleted
NCT03722160
Clinical Study of the Solo Tympanostomy Tube DeviceNo drug interventionstreatmentNot Availableunknown_status
NCT01444391
inVENT-visIOn StudyNo drug interventionstreatmentNot Availablecompleted
NCT00189462
A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Childrenprevention4completed
NCT03916029
Hearing for Learning Initiative - a Health Facilitator Model for Otitis MediaNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT00422929
Eustachian Tube Growth and DevelopmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02703389
Improving Knowledge Translation Upon Emergency Department DischargeNo drug interventionstreatment3completed
NCT05799404
Stapes Footplate Thickness Measured With UHR-CTNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01611246
Earset Healthy Volunteer StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03544138
In-Office Study of the Hummingbird® in Children 6 Months-21 Years OldNo drug interventionstreatmentNot Availablecompleted
NCT01312038
Effect of Simethicone on Eustachian Tube Dysfunctiontreatment2completed