Doramapimod

DB03044InvestigationalSmall molecule

Doramapimod is a P38 MAP kinase inhibitor.

Chemical structure of Doramapimod
Mechanism
Curator reviewed
Formula / weight
C31H37N5O3 · 527.6572 g/mol (avg)
Code names
BIRB-796 · BIRB-796 BS

Resolves to

Compound
UNIIHO1A8B3YVVCAS285983-48-4ChEMBLCHEMBL103667ChEBI40953PubChem156422KEGGD03736
Structure
InChIKeyMVCOAUNKQVWQHZ-UHFFFAOYSA-NSMILESCC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=CC=C(OCCN2CCOCC2)C2=C1C=CC=C2)C(C)(C)C
Targets
Q16539MAPK14P08631HCK

What you can answer from here — as of September 12, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Doramapimod, and which of those have an active Phase 3 trial?

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