Quinazolines
- Name
- Quinazolines
- Accession Number
- DBCAT000883
- Description
Cyclic compounds that include atoms other than carbon in their ring structure.
- Drugs
Drug Drug Description 2X-121 2X-121 is under investigation in clinical trial NCT03562832 (Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRP). Afatinib An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. Altanserin Altanserin is a small molecule drug. The usage of the INN stem '-anserin' in the name indicates that Altanserin is a serotonin receptor antagonist. Altanserin is under investigation in clinical... Apabetalone Apabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease. ATH434 Not Annotated ATX-914 Axt914 is under investigation in clinical trial NCT00417261 (Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.). Avadomide Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma). Butanserin Butanserin is a small molecule drug. The usage of the INN stem '-anserin' in the name indicates that Butanserin is a serotonin receptor antagonist. Butanserin has a monoisotopic molecular weight... Carotegrast methyl Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and Efficacy of AJM300 in Participants With Active Ulcerative Colitis). Dacomitinib A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. Doxazosin An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. Elinogrel Investigated for use/treatment in cardiovascular disorders and myocardial infarction. Erlotinib An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers. Gefitinib A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. Halofuginone For the treatment of scleroderma, cancer, and restenosis. Idelalisib An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). Ketanserin Ketanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer. Lapatinib An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Methaqualone For the treatment of insomnia, and as a sedative and muscle relaxant. Metolazone A thiazide-like diuretic used to treat hypertension. MK-0249 MK0249 has been used in trials studying the treatment of Hypopnea Syndrome, Alzheimer's Disease, Paranoid Schizophrenia, Sleep Apnea, Obstructive, and Excessive Daytime Sleepiness, among others. Moquizone Moquizone is a small molecule drug. The usage of the INN stem '-zone' in the name indicates that Moquizone is a anti-inflammatory analgesic, phenylbutazone derivative. Moquizone has a monoisotopic molecular... Prazosin An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. Selurampanel Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal. SP-8203 SP-8203 has been used in trials studying the treatment of Ischemic Stroke. Terazosin An alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension. Tetrodotoxin For the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence. Tiodazosin Tiodazosin is a small molecule drug. Tiodazosin has a monoisotopic molecular weight of 431.14 Da. Trimetrexate A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. - Drugs & Drug Targets