Toxic Actions

Toxic Actions
Accession Number

A broad category of chemical actions with harmful or deadly effect on living organisms.

DrugDrug Description
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
VidarabineAn antiviral agent used to treat various viral infections.
MitomycinAn antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
TemozolomideAn alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
FenofibrateA peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
ThalidomideA medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
TrimetrexateA folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
LomustineAn alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
DecitabineA chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
PitavastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Hydrogen peroxideA compound used as a disinfectant and sterilizer.
Carbamide peroxideA medication used to loosen ear wax, whiten teeth, and clean oral wounds.
TriclocarbanAn antibacterial agent used in liquid soaps and body washes.
MoxidectinMoxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and...
Carbon monoxideA gas used as a marker of respiratory status in spirometry tests.
AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Polatuzumab vedotinA CD79b antibody conjugate indicated to treat different types of large B-cell lymphoma.
Sacituzumab govitecanSacituzumab govitecan targets TROP-2-expressing cancer cells through a humanized antibody (RS7) before subsequently becoming internalized and releasing the topoisomerase I inhibitor SN-38 to induce DNA damage-mediated apoptosis.
Trastuzumab deruxtecanAn antibody used to treat certain types of unresectable or metastatic HER2 positive breast cancer.
Ferric chlorideNot Annotated
MechlorethamineAn antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
Bisphenol ANot Available
Sulfur dioxideNot Annotated
Gemtuzumab ozogamicinA monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia.
PipobromanFor the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
CycloserineA broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
CrotamitonA topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus.
ChlorambucilA chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas.
RaltitrexedA folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
FloxuridineAn antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
TioguanineA purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
LindaneAn ectoparasiticide and ovicide used in the treatment of Pediculosis humanis capitis (head lice) and Phthirus pubis (crab lice).
TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
AltretamineAn antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
PropylthiouracilA thiourea antithyroid agent used to treat hyperthyroidism.
ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
StavudineA dideoxynucleoside used in the treatment of HIV infection.
Benzyl benzoateA topical treatment for scabies and lice.
MalathionA parasympathomimetic organophosphate used to treat head lice.
Uracil mustardUsed for its antineoplastic properties.
TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
RibavirinA guanosine nucleoside used to treat some forms of Hepatitis C.
DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
DidanosineA reverse transcriptase inhibitor used to treat HIV.
AzacitidineA pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
ZalcitabineA dideoxynucleoside used to treat HIV.
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
MelphalanAn alkylating agent used to treat multiple myeloma, ovarian carcinoma, uveal melanoma with unresectable hepatic metastases, and for high-dose conditioning before hematopoietic stem cell transplant in patients.
FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
CapecitabineA nucleoside metabolic inhibitor indicated to treat different gastrointestinal, including pancreatic cancer, and breast cancer.
ProguanilA medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
EstramustineAn antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
8-azaguanine8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
HadacidinNot Available
2-MethoxyethanolNot Available
Calyculin ANot Available
Cacodylic acidNot Available
BromoformNot Available
TubercidinAn antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic...
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
Malachite GreenNot Available
GlyphosateNot Available
ThiotepaAn alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
ImazaquinNot Available
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
CarboxinA systemic agricultural fungicide and seed treatment agent.
Octylphenoxy polyethoxyethanolNot Available
DantronA drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx.
UrethaneUrethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
Fenoxaprop-ethylChronic angina and Coronary Artery Disease
Chlorotoxin I-131Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma
PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
Trastuzumab emtansineAn antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
IrofulvenInvestigated for use/treatment in brain cancer, breast cancer, endometrial cancer, liver cancer, lung cancer, ovarian cancer, pancreatic cancer, pediatric indications, prostate cancer, and sarcoma.
Inotuzumab ozogamicinAn antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL).
LonidamineInvestigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).
AnilineAniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor...
BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
NiclosamideAn anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
Nonoxynol-9A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception.
CarbazoleNot Available
AcifluorfenAcifluorfen is a protoporphyrinogen oxidase inhibitor.
AtrazineAtrazine is a selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans. Acutely poisoned sheep and cattle may show muscular...
TerbutrynNot Available
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridinePhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
ThiaclopridNot Available
SpinosadA pediculicide used topically to treat head lice.
2-deoxyglucoseAs of July 2013, there is no approved therapeutic indication for 2-deoxyglucose. 2-deoxyglucose may have several potential indications as an adjunct to chemotherapy and radiotherapy in the treatment of solid...
Brentuximab vedotinA CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
CiprofibrateNot Annotated
PodophyllinA cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata).
TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
Phenylacetic acidAn agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle.
Piperonyl butoxideA pesticide used as a potentiator ingredient in the treatment of pediculosis (head lice, body lice or crabs) to boost efficacy of treatment.
HydroquinoneA topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles.
Pyrethrum extractA chrysanthemum flower extract used to treat head, pubic, and body lice.
ChlorineChlorine is a stongly oxidizing agent and the third most electronegative element which belongs to the group of halogens with the atomic number 17 and symbol Cl. Being a yellow-green...
TurpentineA medication used to treat minor aches and pains of muscles and joints.
HypochloriteAn antimicrobial used to treat and prevent infections of the skin and tissue.
Sodium hydroxideUsed to destroy or kill the nail matrix (matrixectomies) .
TrichloroacetateTrichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it...
DiethyltoluamideAn insect repellant, also known as DEET.
Boric acidNo FDA- or EMA-approved therapeutic indications on its own.
AmitrazAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as...
CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
CythioateCythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.
DichlorvosDichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
DoramectinDoramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in...
EprinomectinNot Annotated
FamphurNot Annotated
FenthionFenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
ImidaclopridImidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and...
LufenuronLufenuron is used in veterinary for the control of flea.
NitenpyramNitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly...
PhosmetPhosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,...
RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
AminacrineA slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties.
Recombinant Cholera Toxin B SubunitRecombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
TreosulfanTreosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
DinitrochlorobenzeneDinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
BenznidazoleA trypanocidal agent used to treat Chagas disease.
TriptolideTriptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.
BroxuridineBroxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
Lorvotuzumab mertansineLorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
CordycepinCordycepin has been used in trials studying the treatment of Leukemia.
TemefosDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
CantharidinA natured product indicated to treat molluscum contagiosum
BizelesinBizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
TetrahydrouridineTetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.
OzoneOzone has been used in trials studying the treatment of Mild Asthma and Primary Apical Periodontite.
Methyl pyrrolidoneN Methyl Pyrrolidone is under investigation for the treatment of Multiple Myeloma.
Moxetumomab pasudotoxA CD22-specific antibody conjugated to a truncated exotoxin used to treat relapsed or refractory hairy cell leukemia in patients who have already been treated with a purine nucleoside analog and one other treatment.
Phenethyl IsothiocyanatePhenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
FenpropidinFenpropidin has been investigated for the treatment of Hernia.
LometrexolLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
PrednimustinePrednimustine has been used in trials studying the treatment of Lymphoma.
Buthionine sulfoximineButhionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
DianhydrogalactitolDianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
TrofosfamideTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
NolatrexedNolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
MitolactolMitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
DoxifluridineDoxifluridine has been investigated for the treatment of Stomach Cancer.
NeosaxitoxinNeosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
CarbendazimCarbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
TiazofurineTiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
ThiramThiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for...
TriaziquoneNot Annotated
DimethylphthalateNot Annotated
EtoglucidNot Annotated
ParaoxonNot Annotated
MitobronitolNot Annotated
DeltamethrinNot Annotated
SemustineNot Annotated
CarboquoneNot Annotated
PhenothrinA pyrethroid indicated in the treatment of head lice.
CypermethrinA medication used to treat parasitic skin diseases.
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
TetramethrinNot Annotated
CyfluthrinNot Annotated
Toyocamycin4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
1,2-dichlorobenzene1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
Sodium bisulfiteAn ingredient in parenteral nutrition products for patients with severe liver disorders.
TretamineToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Bisphenol A diglycidyl etherNot Annotated
Hypochlorous acidAn oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
p-AminophenolNot Annotated
Chloric acidNot Annotated
Nickel sulfateNickel sulfate is used in allergenic testing.
DichromateNot Annotated
Potassium triiodideNot Annotated
Peracetic acidA liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
Estramustine phosphateA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
TosylchloramideA chlorinated disinfectant of the genitals and injured skin.
RemdesivirA nucleoside analog used to treat RNA virus infections including COVID-19.
MethamidophosMethamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia in First Remission).
TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
ChlorotoxinChlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
TallimustineAn alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity.
PatulinNot Annotated
CarbarylA medication used in shampoo to remove lice.
Sodium nitrateNot Annotated
StrychnineNot Annotated
ChlorocresolNot Annotated
Phenylmercuric acetatePhenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.
Phorbol 12-myristate 13-acetate diesterPhorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).
5,6-dihydro-5-azacytidineNot Annotated
Cantuzumab mertansineNot Annotated
Minnelide free acidNot Annotated
MinnelideNot Annotated
6-diazo-5-oxo-L-norleucine6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.
DideoxyadenosineNot Annotated
FenvalerateNot Annotated
Arsenite ionNot Annotated
2-UndecanoneNot Available
IcaridinIcaridin is indicated for use to repel insects, such as mosquitoes, biting flies, ticks, chiggers, and fleas, via topical use or over clothing .
Drugs & Drug Targets
Botulinum toxin type ASynaptosomal-associated protein 25target
Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
Botulinum toxin type ASerum albumincarrier
Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PravastatinSolute carrier organic anion transporter family member 2B1transporter
PravastatinP-glycoprotein 1transporter
PravastatinSolute carrier organic anion transporter family member 1A2transporter
PravastatinSolute carrier family 22 member 6transporter
PravastatinSolute carrier family 22 member 8transporter
PravastatinCanalicular multispecific organic anion transporter 1transporter
PravastatinSolute carrier family 22 member 11transporter
PravastatinATP-binding cassette sub-family G member 2transporter
PravastatinSolute carrier family 22 member 7transporter
PravastatinSolute carrier organic anion transporter family member 1B1transporter
PravastatinMonocarboxylate transporter 1transporter
PravastatinBile salt export pumptransporter
PravastatinSolute carrier organic anion transporter family member 1B3transporter
PravastatinHistone deacetylase 2target
VidarabineDNA polymerase catalytic subunittarget
VidarabineThymidine kinasetarget
VidarabineThymidine kinasetarget
VidarabineAdenosine deaminaseenzyme
MitomycinNADPH--cytochrome P450 reductaseenzyme
GemcitabineRibonucleoside-diphosphate reductase large subunittarget
GemcitabineUMP-CMP kinasetarget
GemcitabineThymidylate synthasetarget
GemcitabineCytidine deaminaseenzyme
GemcitabineDeoxycytidine kinaseenzyme
GemcitabineP-glycoprotein 1transporter
GemcitabineMultidrug resistance-associated protein 7transporter
GemcitabineEquilibrative nucleoside transporter 1transporter
GemcitabineSodium/nucleoside cotransporter 1transporter
GemcitabineEquilibrative nucleoside transporter 2transporter
GemcitabineSolute carrier family 28 member 3transporter
GemcitabineThymidine kinase 2, mitochondrialenzyme
GemcitabineUMP-CMP kinaseenzyme
GemcitabineNucleoside diphosphate kinase Aenzyme
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
MethotrexateCarboxypeptidase G2enzyme
IvermectinP-glycoprotein 1transporter
IvermectinMultidrug resistance-associated protein 1transporter
IvermectinCanalicular multispecific organic anion transporter 1transporter
IvermectinATP-binding cassette sub-family G member 2transporter
IvermectinCytochrome P450 3A4enzyme
IvermectinSolute carrier organic anion transporter family member 1B1transporter
IvermectinSolute carrier organic anion transporter family member 1B3transporter
IvermectinCytochrome P450 2D6enzyme
IvermectinCytochrome P450 2E1enzyme
NiacinHydroxycarboxylic acid receptor 2target
NiacinNicotinamide N-methyltransferasetarget
NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
NiacinHydroxycarboxylic acid receptor 3target
NiacinSolute carrier family 22 member 5transporter
NiacinSolute carrier organic anion transporter family member 2B1transporter
NiacinMonocarboxylate transporter 1transporter
NiacinCytochrome P450 2D6enzyme
NiacinSodium-coupled monocarboxylate transporter 1transporter
NiacinMonocarboxylate transporter 4transporter
NiacinThyroxine-binding globulincarrier
NiacinCytochrome P450 3A4enzyme
NiacinCytochrome P450 2E1enzyme
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
TemozolomideSerum albumincarrier
TemozolomideAlpha-1-acid glycoprotein 1carrier
TemozolomideP-glycoprotein 1transporter
TemozolomideATP-binding cassette sub-family G member 2transporter
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinSerum albumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
AzathioprineThiopurine S-methyltransferaseenzyme
AzathioprineXanthine dehydrogenase/oxidaseenzyme
AzathioprineGlutathione S-transferase A1enzyme
AzathioprineGlutathione S-transferase A2enzyme
AzathioprineGlutathione S-transferase Mu 1enzyme
AzathioprineRas-related C3 botulinum toxin substrate 1target
AzathioprineCytochrome P450 1A2enzyme
AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
AzathioprineEquilibrative nucleoside transporter 2transporter
AzathioprineSolute carrier family 28 member 3transporter
AzathioprineP-glycoprotein 1transporter
AzathioprineSolute carrier family 43 member 3transporter
AzathioprineSerum albumincarrier
AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
AzathioprineInosine triphosphate pyrophosphataseenzyme
FenofibratePeroxisome proliferator-activated receptor alphatarget
FenofibrateMatrix metalloproteinase-25target
FenofibrateCytochrome P450 2C8enzyme
FenofibrateCytochrome P450 2C9enzyme
FenofibrateNuclear receptor subfamily 1 group I member 2target
FenofibrateUDP-glucuronosyltransferase 1-9enzyme
FenofibrateBile salt export pumptransporter
FenofibrateSerum albumincarrier
FenofibrateCytochrome P450 2C19enzyme
FenofibrateCytochrome P450 2A6enzyme
FenofibrateLiver carboxylesterase 1enzyme
FenofibrateCarbonyl reductase [NADPH] 1enzyme
FenofibrateAldo-keto reductase family 1 member C1enzyme
FenofibrateAldo-keto reductase family 1 member C2enzyme
FenofibrateAldo-keto reductase family 1 member C3enzyme
FenofibrateAldose reductaseenzyme
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
ThalidomideCytochrome P450 3A4enzyme
ThalidomideCytochrome P450 1A1enzyme
ThalidomideCytochrome P450 2B6enzyme
TrimetrexateDihydrofolate reductasetarget
TrimetrexateFolate transporter 1transporter
LomustineCytochrome P450 3A4enzyme
LomustineCytochrome P450 2D6enzyme
GemfibrozilPeroxisome proliferator-activated receptor alphatarget
GemfibrozilCytochrome P450 2C9enzyme
GemfibrozilCytochrome P450 2C8enzyme
GemfibrozilCytochrome P450 1A2enzyme
GemfibrozilCytochrome P450 2C19enzyme
GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
GemfibrozilCytochrome P450 3A4enzyme
GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
GemfibrozilSolute carrier organic anion transporter family member 1B1target
GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
GemfibrozilSerum albumincarrier
GemfibrozilSolute carrier family 22 member 8target
GemfibrozilSolute carrier organic anion transporter family member 2B1target
GemfibrozilSolute carrier organic anion transporter family member 1B3target
DecitabineDNA (cytosine-5)-methyltransferase 1target
DecitabineDeoxycytidine kinaseenzyme
DecitabineUMP-CMP kinaseenzyme
DecitabineNucleoside diphosphokinaseenzyme
DecitabineCytidine deaminaseenzyme
DecitabineDNA (cytosine-5)-methyltransferase 3Atarget
DecitabineDNA (cytosine-5)-methyltransferase 3Btarget
DecitabineSodium/nucleoside cotransporter 1transporter
DecitabineHistone deacetylasetarget
PitavastatinSolute carrier organic anion transporter family member 1B1transporter
PitavastatinSolute carrier organic anion transporter family member 1B3transporter
PitavastatinUDP-glucuronosyltransferase 2B7enzyme
PitavastatinUDP-glucuronosyltransferase 1-3enzyme
PitavastatinCytochrome P450 2C9enzyme
PitavastatinCytochrome P450 2C8enzyme
Pitavastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PitavastatinSolute carrier organic anion transporter family member 2B1transporter
PitavastatinSodium/bile acid cotransportertransporter
PitavastatinATP-binding cassette sub-family G member 2transporter
PitavastatinP-glycoprotein 1transporter
PitavastatinCanalicular multispecific organic anion transporter 1transporter
PitavastatinSerum albumincarrier
PitavastatinAlpha-1-acid glycoprotein 1carrier
PitavastatinBile salt export pumptransporter
PitavastatinIntegrin alpha-Ltarget
Hydrogen peroxideGlutathione peroxidase 1enzyme
Hydrogen peroxideCatalaseenzyme
Hydrogen peroxideAlkaline phosphatase, germ cell typeenzyme
TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
TriclocarbanCytochrome P450 1A1enzyme
TriclocarbanCytochrome P450 1B1enzyme
MoxidectinCYP2B proteinenzyme
MoxidectinGlutamate-gated chloride channeltarget
MoxidectinGABA-A gated chloride channeltarget
MoxidectinABC transporterstarget
Carbon monoxideMyoglobintarget
Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
AtorvastatinCytochrome P450 3A4enzyme
AtorvastatinDipeptidyl peptidase 4target
AtorvastatinCytochrome P450 2D6enzyme
AtorvastatinCytochrome P450 2C9enzyme
AtorvastatinCytochrome P450 2C19enzyme
AtorvastatinCytochrome P450 3A5enzyme
AtorvastatinCytochrome P450 3A7enzyme
AtorvastatinP-glycoprotein 1transporter
AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
AtorvastatinMultidrug resistance-associated protein 4transporter
AtorvastatinMultidrug resistance-associated protein 5transporter
AtorvastatinMultidrug resistance-associated protein 1transporter
AtorvastatinCytochrome P450 2B6enzyme
AtorvastatinCytochrome P450 2C8enzyme
AtorvastatinAryl hydrocarbon receptortarget
AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
AtorvastatinCanalicular multispecific organic anion transporter 1transporter
AtorvastatinBile salt export pumptransporter
AtorvastatinSerum albumincarrier
AtorvastatinHistone deacetylase 2target
AtorvastatinNuclear receptor subfamily 1 group I member 3target
Polatuzumab vedotinCytochrome P450 3A4enzyme
Polatuzumab vedotinB-cell antigen receptor complex-associated protein beta chaintarget
Polatuzumab vedotinP-glycoprotein 1transporter
Polatuzumab vedotinCytochrome P450 3A5enzyme
Sacituzumab govitecanTumor-associated calcium signal transducer 2target
Sacituzumab govitecanDNA topoisomerase 1target
Sacituzumab govitecanFar upstream element-binding protein 1target
Sacituzumab govitecanUDP-glucuronosyltransferase 1-1enzyme
Trastuzumab deruxtecanP-glycoprotein 1transporter
Trastuzumab deruxtecanHigh affinity immunoglobulin gamma Fc receptor Itarget
Trastuzumab deruxtecanDNA topoisomerase 1target
Trastuzumab deruxtecanLysosomal alpha-glucosidaseenzyme
Trastuzumab deruxtecanDNA topoisomerase 1enzyme
Trastuzumab deruxtecanCathepsin Benzyme
Trastuzumab deruxtecanCathepsin L1enzyme
Trastuzumab deruxtecanCytochrome P450 3A4enzyme
Trastuzumab deruxtecanSolute carrier organic anion transporter family member 1B1transporter
Trastuzumab deruxtecanSolute carrier organic anion transporter family member 1B3transporter
Trastuzumab deruxtecanMultidrug and toxin extrusion protein 2transporter
Trastuzumab deruxtecanMultidrug resistance-associated protein 1transporter
Trastuzumab deruxtecanATP-binding cassette sub-family G member 2transporter
TinidazoleCytochrome P450 3A4enzyme
TinidazoleBile salt export pumptransporter
BusulfanCytochrome P450 3A4enzyme
BusulfanGlutathione S-transferase A2enzyme
BusulfanGlutathione S-transferase A1enzyme
BusulfanGlutathione S-transferase Mu 1enzyme
BusulfanGlutathione S-transferase Penzyme
BusulfanMicrosomal glutathione S-transferase 2enzyme
Bisphenol AEstrogen-related receptor gammatarget
Gemtuzumab ozogamicinMyeloid cell surface antigen CD33target
Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Btarget
Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Atarget
Gemtuzumab ozogamicinHigh affinity immunoglobulin gamma Fc receptor Itarget
DiethylstilbestrolEstrogen receptor alphatarget
DiethylstilbestrolEstrogen-related receptor gammatarget
DiethylstilbestrolCatechol O-methyltransferaseenzyme
DiethylstilbestrolCytochrome P450 19A1enzyme
DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DiethylstilbestrolP-glycoprotein 1transporter
DiethylstilbestrolEstrogen receptor betatarget
DiethylstilbestrolCytochrome P450 3A4enzyme
DiethylstilbestrolCytochrome P450 2C8enzyme
DiethylstilbestrolCytochrome P450 2C9enzyme
DiethylstilbestrolCytochrome P450 2E1enzyme
DiethylstilbestrolSteroid hormone receptor ERR1target
DiethylstilbestrolSteroid hormone receptor ERR2target
DiethylstilbestrolNuclear receptor coactivator 2target
DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DiethylstilbestrolAndrogen receptortarget
DiethylstilbestrolSex hormone-binding globulintarget
DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DiethylstilbestrolBile salt export pumptransporter
CycloserineD-alanine--D-alanine ligase Atarget
CycloserineAlanine racemasetarget
CycloserineAromatic-L-amino-acid decarboxylaseenzyme
CycloserineProton-coupled amino acid transporter 2transporter
CarmustineGlutathione reductase, mitochondrialtarget
ChlorambucilGlutathione S-transferase Penzyme
ChlorambucilSolute carrier organic anion transporter family member 1A2transporter
ChlorambucilGlutathione S-transferases (Cytosolic)enzyme
RaltitrexedThymidylate synthasetarget
RaltitrexedFolylpolyglutamate synthase, mitochondrialtarget
FloxuridineThymidylate synthasetarget
FloxuridineThymidine phosphorylaseenzyme
FloxuridineCytochrome P450 2C9enzyme
FloxuridineThyroxine-binding globulincarrier
TioguanineMultidrug resistance-associated protein 4transporter
TioguanineHypoxanthine-guanine phosphoribosyltransferaseenzyme
LindaneGamma-aminobutyric acid receptor subunit beta-1target
LindaneGlycine receptor subunit alpha-1target
LindaneGlycine receptor subunit alpha-2target
LindaneGlycine receptor subunit alpha-3target
LindaneGlycine receptor subunit betatarget
LindaneGamma-aminobutyric acid receptor subunit beta-3target
LindaneGamma-aminobutyric acid receptor subunit rho-1target
LindaneProgesterone receptortarget
LindaneEstrogen receptor alphatarget
LindaneNuclear receptor subfamily 1 group I member 2target
TrifluridineThymidylate synthasetarget
TrifluridineThymidine kinase, cytosolicenzyme
TrifluridineThymidine phosphorylaseenzyme
TrifluridineSolute carrier family 22 member 6transporter
TrifluridineSodium/nucleoside cotransporter 1transporter
TrifluridineEquilibrative nucleoside transporter 1transporter
TrifluridineEquilibrative nucleoside transporter 2transporter
TrifluridineSerum albumincarrier
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
CyclophosphamideCytochrome P450 2B6enzyme
CyclophosphamideCytochrome P450 2C9enzyme
CyclophosphamideCytochrome P450 3A4enzyme
CyclophosphamideCytochrome P450 2C19enzyme
CyclophosphamideCytochrome P450 2A6enzyme
CyclophosphamideCytochrome P450 2C18enzyme
CyclophosphamideCytochrome P450 2C8enzyme
CyclophosphamideCytochrome P450 3A5enzyme
CyclophosphamideNuclear receptor subfamily 1 group I member 2target
FluorouracilThymidylate synthasetarget
FluorouracilCytochrome P450 1A2enzyme
FluorouracilThymidine phosphorylaseenzyme
FluorouracilSerum albumincarrier
FluorouracilCytochrome P450 2C9enzyme
FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
FluorouracilUridine phosphorylase 1enzyme
FluorouracilUridine phosphorylase 2enzyme
FluorouracilCytochrome P450 2A6enzyme
FluorouracilCytochrome P450 2C8enzyme
FluorouracilMethylenetetrahydrofolate reductaseenzyme
FluorouracilThymidylate synthaseenzyme
FluorouracilUridine 5'-monophosphate synthaseenzyme
FluorouracilSolute carrier family 22 member 7transporter
FluorouracilEquilibrative nucleoside transporter 1transporter
FluorouracilATP-binding cassette sub-family G member 2transporter
FluorouracilCanalicular multispecific organic anion transporter 2transporter
FluorouracilMultidrug resistance-associated protein 4transporter
FluorouracilMultidrug resistance-associated protein 5transporter
FluorouracilThyroxine-binding globulincarrier
PropylthiouracilThyroid peroxidasetarget
PropylthiouracilDopamine beta-hydroxylaseenzyme
PropylthiouracilCytochrome P450 1A1enzyme
ClofarabineDNA polymerase alpha catalytic subunittarget
ClofarabineRibonucleoside-diphosphate reductase large subunittarget
ClofarabineDeoxycytidine kinaseenzyme
ClofarabineATP-binding cassette sub-family G member 2transporter
StavudineSolute carrier family 22 member 6transporter
StavudineReverse transcriptase/RNaseHtarget
StavudineSodium/nucleoside cotransporter 1transporter
StavudineSerum albumincarrier
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
Uracil mustardDNAtarget
TazaroteneRetinoic acid receptor alphatarget
TazaroteneRetinoic acid receptor RXR-betatarget
TazaroteneRetinoic acid receptor gammatarget
TazaroteneRetinoic acid receptor betatarget
TazaroteneCytochrome P450 2C8enzyme
RibavirinRNA-directed RNA polymerase Ltarget
RibavirinRNA-directed RNA polymerase catalytic subunittarget
RibavirinInosine-5'-monophosphate dehydrogenase 1target
RibavirinGenome polyproteintarget
RibavirinInosine-5'-monophosphate dehydrogenase 2target
RibavirinAdenosine kinaseenzyme
RibavirinEquilibrative nucleoside transporter 1transporter
RibavirinSolute carrier family 28 member 3transporter
RibavirinCytosolic purine 5'-nucleotidaseenzyme
DacarbazineDNA polymerase alpha subunit Btarget
DacarbazineCytochrome P450 1A1enzyme
DacarbazineCytochrome P450 1A2enzyme
DacarbazineCytochrome P450 2E1enzyme
Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DidanosineSolute carrier family 22 member 6transporter
DidanosinePurine nucleoside phosphorylasetarget
DidanosineReverse transcriptase/RNaseHtarget
DidanosineEquilibrative nucleoside transporter 1transporter
DidanosineEquilibrative nucleoside transporter 2transporter
DidanosineSerum albumincarrier
AzacitidineDNA (cytosine-5)-methyltransferase 1target
AzacitidineCytidine deaminaseenzyme
ZalcitabineDeoxycytidine kinaseenzyme
ZalcitabineSolute carrier family 22 member 6transporter
ZalcitabineSolute carrier family 22 member 7transporter
ZalcitabineReverse transcriptase/RNaseHtarget
ZalcitabineEquilibrative nucleoside transporter 1transporter
ZalcitabineEquilibrative nucleoside transporter 2transporter
ZalcitabineSerum albumincarrier
CytarabineDNA polymerase betatarget
CytarabineCytidine deaminaseenzyme
CytarabineSolute carrier family 22 member 4transporter
CytarabineMultidrug resistance-associated protein 7transporter
CytarabineEquilibrative nucleoside transporter 1transporter
CytarabineCytochrome P450 3A4enzyme
CytarabineDeoxycytidine kinaseenzyme
CytarabineDeoxycytidylate deaminaseenzyme
MetyraponeCamphor 5-monooxygenasetarget
MetyraponeCytochrome P450 11B2, mitochondrialenzyme
MetyraponeCytochrome P450 2A6enzyme
MetyraponeCytochrome P450 3A4enzyme
MetyraponeCanalicular multispecific organic anion transporter 2transporter
MetyraponeCytochrome P450 11B1, mitochondrialtarget
MetyraponeCytochrome P450 11B1, mitochondrialenzyme
MetyraponeCytochrome P450 2E1enzyme
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineSolute carrier family 22 member 8transporter
MercaptopurineMultidrug resistance-associated protein 4transporter
MercaptopurineMultidrug resistance-associated protein 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
MelphalanSolute carrier family 22 member 3transporter
MelphalanLarge neutral amino acids transporter small subunit 1transporter
MelphalanSerum albumincarrier
MelphalanAlpha-1-acid glycoprotein 1carrier
MelphalanAsc-type amino acid transporter 1transporter
FludarabineDNA polymerase alpha catalytic subunittarget
FludarabineRibonucleoside-diphosphate reductase large subunittarget
FludarabineEquilibrative nucleoside transporter 1transporter
FludarabineDeoxycytidine kinasetarget
FludarabineSolute carrier family 28 member 3transporter
FlucytosineThymidylate synthasetarget
FlucytosineDNA (cytosine-5)-methyltransferase 1target
CapecitabineThymidylate synthasetarget
CapecitabineThymidine phosphorylaseenzyme
CapecitabineCytidine deaminaseenzyme
CapecitabineLiver carboxylesterase 1enzyme
CapecitabineCytochrome P450 2C9enzyme
CapecitabineSerum albumincarrier
CapecitabineUridine phosphorylase 1enzyme
CapecitabineUridine phosphorylase 2enzyme
ProguanilBifunctional dihydrofolate reductase-thymidylate synthasetarget
ProguanilDihydrofolate reductasetarget
ProguanilCytochrome P450 2C19enzyme
ProguanilCytochrome P450 2D6enzyme
ProguanilCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2B6enzyme
IfosfamideCytochrome P450 3A4enzyme
IfosfamideCytochrome P450 3A5enzyme
IfosfamideCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2C8enzyme
IfosfamideCytochrome P450 2A6enzyme
IfosfamideCytochrome P450 2C19enzyme
IfosfamideCytochrome P450 2C18enzyme
IfosfamideProstaglandin G/H synthase 1enzyme
IfosfamideNuclear receptor subfamily 1 group I member 2target
EstramustineEstrogen receptor betatarget
EstramustineEstrogen receptor alphatarget
EstramustineMicrotubule-associated protein 2target
EstramustineMicrotubule-associated protein 1Atarget
EstramustineP-glycoprotein 1transporter
EstramustineCytochrome P450 3A4enzyme
8-azaguaninePurine nucleoside phosphorylasetarget
8-azaguanineCytochrome P450 1A2enzyme
HadacidinAdenylosuccinate synthetasetarget
HadacidinAdenylosuccinate synthetase isozyme 1target
HadacidinAdenylosuccinate synthetasetarget
Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
Cacodylic acidGag-Pol polyproteintarget
Cacodylic acidNitric oxide synthase, endothelialtarget
Cacodylic acidAldose reductasetarget
Cacodylic acidGuanine nucleotide-binding protein G(t) subunit alpha-1target
TubercidinPurine nucleoside phosphorylase DeoD-typetarget
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
Malachite GreenHTH-type transcriptional regulator QacRtarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
GlyphosateCytochrome P450 19A1target
GlyphosateSerum albumincarrier
ThiotepaCytochrome P450 2B6enzyme
ThiotepaCytochrome P450 3A4enzyme
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
Octylphenoxy polyethoxyethanolTroponin C, skeletal muscletarget
DantronSerum albumincarrier
UrethaneCytosolic phospholipase A2enzyme
UrethaneAldehyde oxidaseenzyme
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
TrabectedinCytochrome P450 3A4enzyme
TrabectedinCytochrome P450 2C9enzyme
TrabectedinCytochrome P450 2D6enzyme
TrabectedinCytochrome P450 2E1enzyme
TrabectedinCytochrome P450 2C19enzyme
TrabectedinProstaglandin G/H synthase 1enzyme
TetrodotoxinSodium channel protein type 1 subunit alphatarget
TetrodotoxinSodium channel protein type 2 subunit alphatarget
TetrodotoxinSodium channel protein type 3 subunit alphatarget
TetrodotoxinSodium channel protein type 8 subunit alphatarget
Fenoxaprop-ethylNitric oxide synthase, inducibletarget
PalifosfamideDNA (cytosine-5)-methyltransferase 1target
Trastuzumab emtansineReceptor tyrosine-protein kinase erbB-2target
Trastuzumab emtansineP-glycoprotein 1transporter
Trastuzumab emtansineCytochrome P450 3A4enzyme
Trastuzumab emtansineCytochrome P450 3A5enzyme
IrofulvenFar upstream element-binding protein 1target
Inotuzumab ozogamicinP-glycoprotein 1transporter
Inotuzumab ozogamicinB-cell receptor CD22target
LonidamineCystic fibrosis transmembrane conductance regulatortarget
AnilineCytochrome P450 2E1enzyme
AnilineSerum albumintarget
BendamustineCytochrome P450 1A2enzyme
NiclosamideCytochrome P450 2C9enzyme
NiclosamideCytochrome P450 1A2enzyme
Nonoxynol-9Prostaglandin G/H synthase 2enzyme
CarbazoleFerredoxin CarActarget
CarbazoleTerminal oxygenase component of carbazoletarget
AcifluorfenProtoporphyrinogen oxidasetarget
AcifluorfenProtoporphyrinogen oxidasetarget
AtrazinePhotosynthetic reaction center cytochrome c subunittarget
AtrazineReaction center protein H chaintarget
AtrazineReaction center protein L chaintarget
AtrazineReaction center protein M chaintarget
TerbutrynPhotosynthetic reaction center cytochrome c subunittarget
TerbutrynReaction center protein H chaintarget
TerbutrynReaction center protein L chaintarget
TerbutrynReaction center protein M chaintarget
TerbutrynReaction center protein L chaintarget
TerbutrynReaction center protein M chaintarget
TerbutrynReaction center protein H chaintarget
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineEstrogen receptor alphatarget
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineNuclear receptor coactivator 2target
Puromycin60S ribosomal protein L10-liketarget
Puromycin60S ribosomal protein L13atarget
Puromycin60S ribosomal protein L23target
Puromycin60S ribosomal protein L15target
Puromycin60S ribosomal protein L19target
Puromycin60S ribosomal protein L23atarget
PuromycinProbable ribosome biogenesis protein RLP24target
Puromycin60S ribosomal protein L26-like 1target
Puromycin60S ribosomal protein L8target
Puromycin60S ribosomal protein L37target
Puromycin60S ribosomal protein L3target
Puromycin60S ribosomal protein L11target
PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
ThiaclopridCHRNA7-FAM7A fusion proteintarget
2-deoxyglucoseSolute carrier family 2, facilitated glucose transporter member 1transporter
Brentuximab vedotinTumor necrosis factor receptor superfamily member 8target
Brentuximab vedotinCytochrome P450 3A4enzyme
Brentuximab vedotinATP-binding cassette sub-family B member 5transporter
CiprofibratePeroxisome proliferator-activated receptor alphatarget
TegafurCytochrome P450 2A6enzyme
TegafurThymidylate synthasetarget
TegafurCytochrome P450 1A2enzyme
TegafurCytochrome P450 2C8enzyme
TegafurCytochrome P450 2E1enzyme
TegafurCytochrome P450 3A5enzyme
TegafurThyroxine-binding globulincarrier
Phenylacetic acidLiver carboxylesterase 1enzyme
HydroquinoneSerum albumincarrier
HydroquinoneLysosomal alpha-glucosidaseenzyme
HydroquinoneCysteinyl leukotriene receptor 1target
Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
TurpentineMitogen-activated protein kinase 1target
DichlorvosSerum albumincarrier
DoramectinCytochrome P450 3A4enzyme
EprinomectinCytochrome P450 3A4enzyme
ImidaclopridCHRNA7-FAM7A fusion proteintarget
DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DinitrochlorobenzeneGlutathione S-transferase Ptarget
Lorvotuzumab mertansineCytochrome P450 3A4enzyme
CantharidinAryl hydrocarbon receptortarget
Moxetumomab pasudotoxB-cell receptor CD22target
Moxetumomab pasudotoxElongation factor 2target
Phenethyl IsothiocyanateActin, aortic smooth muscletarget
Phenethyl IsothiocyanateActin, cytoplasmic 1target
Phenethyl IsothiocyanateATP synthase subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit e, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit g, mitochondrialtarget
Phenethyl IsothiocyanateCytochrome b5 type Btarget
Phenethyl IsothiocyanateDiablo homolog, mitochondrialtarget
Phenethyl IsothiocyanateF-box only protein 41target
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ftarget
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ktarget
Phenethyl IsothiocyanateHeat shock 70 kDa protein 4target
Phenethyl IsothiocyanateHeat shock protein beta-1target
Phenethyl Isothiocyanate10 kDa heat shock protein, mitochondrialtarget
Phenethyl IsothiocyanateHeat shock protein 105 kDatarget
Phenethyl IsothiocyanateNADH-ubiquinone oxidoreductase chain 1target
Phenethyl IsothiocyanateNuclear migration protein nudCtarget
Phenethyl IsothiocyanatePappalysin-1target
Phenethyl IsothiocyanateProteasome subunit alpha type-3target
Phenethyl Isothiocyanate26S protease regulatory subunit 6Atarget
Phenethyl IsothiocyanateRan-specific GTPase-activating proteintarget
Phenethyl IsothiocyanateProtein S100-A10target
Phenethyl IsothiocyanateSplicing factor 3A subunit 3target
Phenethyl IsothiocyanateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1target
Phenethyl IsothiocyanateSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateTumor protein D54target
Phenethyl IsothiocyanateTropomyosin alpha-1 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-3 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-4 chaintarget
Phenethyl IsothiocyanateTubulin alpha-1A chaintarget
Phenethyl IsothiocyanateTubulin alpha 3C/D chaintarget
Phenethyl IsothiocyanateTubulin alpha-4A chaintarget
Phenethyl IsothiocyanateTubulin beta-1 chaintarget
Phenethyl IsothiocyanateTubulin beta-2A chaintarget
Phenethyl IsothiocyanateTubulin beta-3 chaintarget
Phenethyl IsothiocyanateTubulin beta-4B chaintarget
Phenethyl IsothiocyanateThioredoxintarget
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase isozyme L1target
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase 14target
Phenethyl IsothiocyanateTransitional endoplasmic reticulum ATPasetarget
Phenethyl IsothiocyanateVimentintarget
Phenethyl Isothiocyanate14-3-3 protein beta/alphatarget
Phenethyl Isothiocyanate14-3-3 protein epsilontarget
Phenethyl Isothiocyanate14-3-3 protein etatarget
Phenethyl Isothiocyanate14-3-3 protein thetatarget
Phenethyl Isothiocyanate14-3-3 protein zeta/deltatarget
LometrexolDihydrofolate reductasetarget
CarbendazimCytochrome P450 19A1enzyme
CarbendazimAryl hydrocarbon receptortarget
BioallethrinVoltage-gated sodium channel alpha subunittarget
BioallethrinSodium channel proteintarget
BioallethrinVoltage-dependent calcium channeltarget
BioallethrinVoltage-dependent T-type calcium channeltarget
BioallethrinVoltage-dependent P/Q-type calcium channeltarget
BioallethrinVoltage-dependent L-type calcium channeltarget
BioallethrinCytochrome P450 2C8enzyme
BioallethrinCytochrome P450 2C9enzyme
BioallethrinCytochrome P450 2C19enzyme
BioallethrinCytochrome P450 3A4enzyme
BioallethrinCytochrome P450 2A1enzyme
BioallethrinCytochrome P450 1A1enzyme
BioallethrinCytochrome P450 2C6enzyme
BioallethrinCytochrome P450 2C11enzyme
BioallethrinCytochrome P450 3A1enzyme
BioallethrinCytochrome P450 3A2enzyme
1,2-dichlorobenzeneCytochrome P450 2E1enzyme
Bisphenol A diglycidyl etherCation channel sperm-associated protein 1target
RemdesivirReplicase polyprotein 1abtarget
RemdesivirRNA-directed RNA polymerase Ltarget
RemdesivirCytochrome P450 2C8enzyme
RemdesivirCytochrome P450 2D6enzyme
RemdesivirCytochrome P450 3A4enzyme
RemdesivirSolute carrier organic anion transporter family member 1B1transporter
RemdesivirP-glycoprotein 1transporter
RemdesivirSolute carrier organic anion transporter family member 1B3transporter
RemdesivirBile salt export pumptransporter
RemdesivirMultidrug resistance-associated protein 4transporter
RemdesivirSodium/bile acid cotransportertransporter
RemdesivirLiver carboxylesterase 1enzyme
RemdesivirLysosomal protective proteinenzyme
RemdesivirReplicase polyprotein 1abtarget
RemdesivirReplicase polyprotein 1abtarget
RemdesivirMultidrug and toxin extrusion protein 1transporter
2-UndecanoneAcyl-coenzyme A thioesterase 13target
IcaridinOdorant binding proteintarget