Identification

Summary

Anthoxanthum odoratum pollen is an extract from Anthoxanthum odoratum pollen used in allergy testing.

Brand Names
Oralair 100, Oralair 300, Oralair Children and Adolescents Sample Kit
Generic Name
Anthoxanthum odoratum pollen
DrugBank Accession Number
DB10404
Background

Anthoxanthum odoratum pollen is the pollen of the Anthoxanthum odoratum plant. Anthoxanthum odoratum pollen is mainly used in allergenic testing.

Type
Biotech
Groups
Approved
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Standardized sweet vernal grass pollen
  • Sweet vernal grass pollen extract

Pharmacology

Indication

Anthoxanthum odoratum pollen is an allergen extract included in an allergenic testing product called ORALAIR. It is indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen38 specific IgE antibodies for any of the five grass species contained in this product. ORALAIR is approved for use in persons 5 through 65 years of age.1

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Acebutolol.
AtenololThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Atenolol.
BenazeprilThe risk or severity of adverse effects can be increased when Benazepril is combined with Anthoxanthum odoratum pollen.
BetaxololThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Betaxolol.
BisoprololThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Bisoprolol.
CaptoprilThe risk or severity of adverse effects can be increased when Captopril is combined with Anthoxanthum odoratum pollen.
CarvedilolThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Carvedilol.
CeliprololThe risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Celiprolol.
CilazaprilThe risk or severity of adverse effects can be increased when Cilazapril is combined with Anthoxanthum odoratum pollen.
EnalaprilThe risk or severity of adverse effects can be increased when Enalapril is combined with Anthoxanthum odoratum pollen.
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Food Interactions
Not Available

Products

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dosage, form, labeller, route of administration, and marketing period.
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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Allergenic Extract - Standardized Grass Pollen - Sweet VernalLiquid100000 unit / mLIntradermal; SubcutaneousGreer Laboratories2000-10-30Not applicableCanada flag
Allergenic Extract - Standardized Grass Pollen - Sweet VernalLiquid10000 unit / mLIntradermal; SubcutaneousGreer LaboratoriesNot applicableNot applicableCanada flag
Allergenic Extract - Standardized Sweet Vernal Grass PollenLiquid100000 unit / mLIntradermal; Percutaneous; SubcutaneousAlk Abello, Inc.2009-07-30Not applicableCanada flag
OralairTablet100 [IR]SublingualStallergenes Canada Inc2012-07-26Not applicableCanada flag
OralairTablet300 [IR]SublingualStallergenes Canada Inc2012-07-26Not applicableCanada flag
Standardized Grass Pollen - Sweet Vernal Grass (100,000 Bau/ml)Solution100000 unitPercutaneous; SubcutaneousJubilant Hollisterstier Llc2000-10-18Not applicableCanada flag
Standardized Grass Pollen, Sweet Vernal GrassInjection, solution1000 [BAU]/1mLIntradermalJubilant Hollisterstier Llc1998-01-15Not applicableUS flag
Standardized Grass Pollen, Sweet Vernal GrassInjection, solution10000 [BAU]/1mLPercutaneous; SubcutaneousJubilant Hollisterstier Llc1998-01-15Not applicableUS flag
Standardized Grass Pollen, Sweet Vernal GrassInjection, solution100 [BAU]/1mLIntradermalJubilant Hollisterstier Llc1998-01-15Not applicableUS flag
Standardized Grass Pollen, Sweet Vernal GrassInjection, solution100000 [BAU]/1mLPercutaneous; SubcutaneousJubilant Hollisterstier Llc1998-01-15Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
5 Grass MixAnthoxanthum odoratum pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Phleum pratense pollen (5000 [PNU]/1mL) + Poa pratensis pollen (5000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixAnthoxanthum odoratum pollen (100 [PNU]/1mL) + Agrostis gigantea pollen (100 [PNU]/1mL) + Dactylis glomerata pollen (100 [PNU]/1mL) + Phleum pratense pollen (100 [PNU]/1mL) + Poa pratensis pollen (100 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixAnthoxanthum odoratum pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Phleum pratense pollen (1000 [PNU]/1mL) + Poa pratensis pollen (1000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixAnthoxanthum odoratum pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
7 Standardized Grass Pollen MixAnthoxanthum odoratum pollen (14285.714 [BAU]/1mL) + Agrostis gigantea pollen (14285.714 [BAU]/1mL) + Dactylis glomerata pollen (14285.714 [BAU]/1mL) + Festuca pratensis pollen (14285.714 [BAU]/1mL) + Lolium perenne pollen (14285.714 [BAU]/1mL) + Phleum pratense pollen (14285.714 [BAU]/1mL) + Poa pratensis pollen (14285.714 [BAU]/1mL)SolutionIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1968-09-15Not applicableUS flag
7 Standardized Grass Pollen MixAnthoxanthum odoratum pollen (1428.5714 [BAU]/1mL) + Agrostis gigantea pollen (1428.5714 [BAU]/1mL) + Dactylis glomerata pollen (1428.5714 [BAU]/1mL) + Festuca pratensis pollen (1428.5714 [BAU]/1mL) + Lolium perenne pollen (1428.5714 [BAU]/1mL) + Phleum pratense pollen (1428.5714 [BAU]/1mL) + Poa pratensis pollen (1428.5714 [BAU]/1mL)SolutionIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1968-09-15Not applicableUS flag
9 Southern Grass Pollen MixAnthoxanthum odoratum pollen (11111.11111 [BAU]/1mL) + Agrostis gigantea pollen (11111.11111 [BAU]/1mL) + Cynodon dactylon pollen (11111.11111 [BAU]/1mL) + Dactylis glomerata pollen (11111.11111 [BAU]/1mL) + Festuca pratensis pollen (11111.11111 [BAU]/1mL) + Lolium perenne pollen (11111.11111 [BAU]/1mL) + Phleum pratense pollen (11111.11111 [BAU]/1mL) + Poa pratensis pollen (11111.11111 [BAU]/1mL) + Sorghum halepense pollen (11111.11111 [BAU]/1mL)SolutionIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1968-09-15Not applicableUS flag
Allergenic Extract - Mixture Of 5 Standardized Grass PollenAnthoxanthum odoratum pollen (20000 unit / mL) + Agrostis gigantea pollen (20000 unit / mL) + Dactylis glomerata pollen (20000 unit / mL) + Phleum pratense pollen (20000 unit / mL) + Poa pratensis pollen (20000 unit / mL)LiquidIntradermal; Percutaneous; SubcutaneousAlk Abello, Inc.2009-07-30Not applicableCanada flag
Allergenic Extracts - 7 Grass MixAnthoxanthum odoratum pollen (10000 unit / mL) + Agrostis gigantea pollen (10000 unit / mL) + Dactylis glomerata pollen (10000 unit / mL) + Festuca pratensis pollen (10000 unit / mL) + Lolium perenne pollen (10000 unit / mL) + Phleum pratense pollen (10000 unit / mL) + Poa pratensis pollen (10000 unit / mL)LiquidSubcutaneousGreer Laboratories2014-09-25Not applicableCanada flag
Allergenic Extracts - 7 Grass MixAnthoxanthum odoratum pollen (100000 unit / mL) + Agrostis gigantea pollen (100000 unit / mL) + Dactylis glomerata pollen (100000 unit / mL) + Festuca pratensis pollen (100000 unit / mL) + Lolium perenne pollen (100000 unit / mL) + Phleum pratense pollen (100000 unit / mL) + Poa pratensis pollen (100000 unit / mL)LiquidSubcutaneousGreer Laboratories2014-06-02Not applicableCanada flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
2KIK19R45Y
CAS number
Not Available

References

General References
  1. FDA Approved Drug Products: ORALAIR 6 (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract) Tablet for Sublingual Use [Link]
PubChem Substance
347910578
RxNav
851898

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentAllergic Reaction1
Not AvailableCompletedNot AvailableAllergic Reaction1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionSubcutaneous
SolutionIntradermal; Percutaneous; Subcutaneous
LiquidIntradermal; Percutaneous; Subcutaneous
LiquidIntradermal; Subcutaneous10000 unit / mL
LiquidIntradermal; Subcutaneous100000 unit / mL
LiquidIntradermal; Percutaneous; Subcutaneous100000 unit / mL
LiquidSubcutaneous
KitSublingual
TabletSublingual100 [IR]
TabletSublingual300 [IR]
Tablet, orally disintegratingSublingual
Injection, solutionPercutaneous
TabletSublingual
SolutionPercutaneous; Subcutaneous100000 unit
Injection, solutionIntradermal
Injection, solutionPercutaneous; Subcutaneous
Injection, solutionIntradermal100 [BAU]/1mL
Injection, solutionIntradermal1000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous10000 [BAU]/1mL
InjectionCutaneous; Intradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous10000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous10000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous100000 [BAU]/1mL
Injection, solutionSubcutaneous10000 [BAU]/1mL
Injection, solutionSubcutaneous100000 [BAU]/1mL
SolutionPercutaneous10000 [BAU]/1mL
SolutionPercutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 01, 2015 20:03 / Updated at December 01, 2022 23:18