Anthoxanthum odoratum pollen

Identification

Summary

Anthoxanthum odoratum pollen is an extract from Anthoxanthum odoratum pollen used in allergy testing.

Brand Names

Oralair 100, Oralair 300, Oralair Children and Adolescents Sample Kit

Generic Name

Anthoxanthum odoratum pollen

DrugBank Accession Number

DB10404

Background

Anthoxanthum odoratum pollen is the pollen of the Anthoxanthum odoratum plant. Anthoxanthum odoratum pollen is mainly used in allergenic testing.

Type

Biotech

Groups

Approved

Biologic Classification

Allergenics
Allergen Extract

Synonyms

• Standardized sweet vernal grass pollen
• Sweet vernal grass pollen extract

Pharmacology

Indication

Anthoxanthum odoratum pollen is an allergen extract included in an allergenic testing product called ORALAIR. It is indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen38 specific IgE antibodies for any of the five grass species contained in this product. ORALAIR is approved for use in persons 5 through 65 years of age.¹

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Associated Conditions

• Allergic Rhinitis Due to Pollen

Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drug	Interaction
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Acebutolol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Acebutolol.
Atenolol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Atenolol.
Benazepril	The risk or severity of adverse effects can be increased when Benazepril is combined with Anthoxanthum odoratum pollen.
Betaxolol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Betaxolol.
Bisoprolol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Bisoprolol.
Captopril	The risk or severity of adverse effects can be increased when Captopril is combined with Anthoxanthum odoratum pollen.
Carvedilol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Carvedilol.
Celiprolol	The risk of a hypersensitivity reaction to Anthoxanthum odoratum pollen is increased when it is combined with Celiprolol.
Cilazapril	The risk or severity of adverse effects can be increased when Cilazapril is combined with Anthoxanthum odoratum pollen.
Enalapril	The risk or severity of adverse effects can be increased when Enalapril is combined with Anthoxanthum odoratum pollen.

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Food Interactions

Not Available

Products

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Brand Name Prescription Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Allergenic Extract - Standardized Grass Pollen - Sweet Vernal	Liquid	100000 unit / mL	Intradermal; Subcutaneous	Greer Laboratories	2000-10-30	Not applicable
Allergenic Extract - Standardized Grass Pollen - Sweet Vernal	Liquid	10000 unit / mL	Intradermal; Subcutaneous	Greer Laboratories	Not applicable	Not applicable
Allergenic Extract - Standardized Sweet Vernal Grass Pollen	Liquid	100000 unit / mL	Intradermal; Percutaneous; Subcutaneous	Alk Abello, Inc.	2009-07-30	Not applicable
Oralair	Tablet	100 [IR]	Sublingual	Stallergenes Canada Inc	2012-07-26	Not applicable
Oralair	Tablet	300 [IR]	Sublingual	Stallergenes Canada Inc	2012-07-26	Not applicable
Standardized Grass Pollen - Sweet Vernal Grass (100,000 Bau/ml)	Solution	100000 unit	Percutaneous; Subcutaneous	Jubilant Hollisterstier Llc	2000-10-18	Not applicable
Standardized Grass Pollen, Sweet Vernal Grass	Injection, solution	1000 [BAU]/1mL	Intradermal	Jubilant Hollisterstier Llc	1998-01-15	Not applicable
Standardized Grass Pollen, Sweet Vernal Grass	Injection, solution	10000 [BAU]/1mL	Percutaneous; Subcutaneous	Jubilant Hollisterstier Llc	1998-01-15	Not applicable
Standardized Grass Pollen, Sweet Vernal Grass	Injection, solution	100 [BAU]/1mL	Intradermal	Jubilant Hollisterstier Llc	1998-01-15	Not applicable
Standardized Grass Pollen, Sweet Vernal Grass	Injection, solution	100000 [BAU]/1mL	Percutaneous; Subcutaneous	Jubilant Hollisterstier Llc	1998-01-15	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
5 Grass Mix	Anthoxanthum odoratum pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Phleum pratense pollen (5000 [PNU]/1mL) + Poa pratensis pollen (5000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
5 Grass Mix	Anthoxanthum odoratum pollen (100 [PNU]/1mL) + Agrostis gigantea pollen (100 [PNU]/1mL) + Dactylis glomerata pollen (100 [PNU]/1mL) + Phleum pratense pollen (100 [PNU]/1mL) + Poa pratensis pollen (100 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
5 Grass Mix	Anthoxanthum odoratum pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Phleum pratense pollen (1000 [PNU]/1mL) + Poa pratensis pollen (1000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
5 Grass Mix	Anthoxanthum odoratum pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
7 Standardized Grass Pollen Mix	Anthoxanthum odoratum pollen (14285.714 [BAU]/1mL) + Agrostis gigantea pollen (14285.714 [BAU]/1mL) + Dactylis glomerata pollen (14285.714 [BAU]/1mL) + Festuca pratensis pollen (14285.714 [BAU]/1mL) + Lolium perenne pollen (14285.714 [BAU]/1mL) + Phleum pratense pollen (14285.714 [BAU]/1mL) + Poa pratensis pollen (14285.714 [BAU]/1mL)	Solution	Intradermal; Percutaneous; Subcutaneous	Greer Laboratories, Inc.	1968-09-15	Not applicable
7 Standardized Grass Pollen Mix	Anthoxanthum odoratum pollen (1428.5714 [BAU]/1mL) + Agrostis gigantea pollen (1428.5714 [BAU]/1mL) + Dactylis glomerata pollen (1428.5714 [BAU]/1mL) + Festuca pratensis pollen (1428.5714 [BAU]/1mL) + Lolium perenne pollen (1428.5714 [BAU]/1mL) + Phleum pratense pollen (1428.5714 [BAU]/1mL) + Poa pratensis pollen (1428.5714 [BAU]/1mL)	Solution	Intradermal; Percutaneous; Subcutaneous	Greer Laboratories, Inc.	1968-09-15	Not applicable
9 Southern Grass Pollen Mix	Anthoxanthum odoratum pollen (11111.11111 [BAU]/1mL) + Agrostis gigantea pollen (11111.11111 [BAU]/1mL) + Cynodon dactylon pollen (11111.11111 [BAU]/1mL) + Dactylis glomerata pollen (11111.11111 [BAU]/1mL) + Festuca pratensis pollen (11111.11111 [BAU]/1mL) + Lolium perenne pollen (11111.11111 [BAU]/1mL) + Phleum pratense pollen (11111.11111 [BAU]/1mL) + Poa pratensis pollen (11111.11111 [BAU]/1mL) + Sorghum halepense pollen (11111.11111 [BAU]/1mL)	Solution	Intradermal; Percutaneous; Subcutaneous	Greer Laboratories, Inc.	1968-09-15	Not applicable
Allergenic Extract - Mixture Of 5 Standardized Grass Pollen	Anthoxanthum odoratum pollen (20000 unit / mL) + Agrostis gigantea pollen (20000 unit / mL) + Dactylis glomerata pollen (20000 unit / mL) + Phleum pratense pollen (20000 unit / mL) + Poa pratensis pollen (20000 unit / mL)	Liquid	Intradermal; Percutaneous; Subcutaneous	Alk Abello, Inc.	2009-07-30	Not applicable
Allergenic Extracts - 7 Grass Mix	Anthoxanthum odoratum pollen (10000 unit / mL) + Agrostis gigantea pollen (10000 unit / mL) + Dactylis glomerata pollen (10000 unit / mL) + Festuca pratensis pollen (10000 unit / mL) + Lolium perenne pollen (10000 unit / mL) + Phleum pratense pollen (10000 unit / mL) + Poa pratensis pollen (10000 unit / mL)	Liquid	Subcutaneous	Greer Laboratories	2014-09-25	Not applicable
Allergenic Extracts - 7 Grass Mix	Anthoxanthum odoratum pollen (100000 unit / mL) + Agrostis gigantea pollen (100000 unit / mL) + Dactylis glomerata pollen (100000 unit / mL) + Festuca pratensis pollen (100000 unit / mL) + Lolium perenne pollen (100000 unit / mL) + Phleum pratense pollen (100000 unit / mL) + Poa pratensis pollen (100000 unit / mL)	Liquid	Subcutaneous	Greer Laboratories	2014-06-02	Not applicable

Categories

Drug Categories

• Allergenic Extracts
• Cell-mediated Immunity
• Grass Pollen Allergen Extracts
• Increased Histamine Release
• Increased IgG Production
• Standardized Pollen Allergenic Extract

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

2KIK19R45Y

CAS number

Not Available

References

General References

1. FDA Approved Drug Products: ORALAIR 6 (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract) Tablet for Sublingual Use [Link]

External Links

PubChem Substance

347910578

RxNav

851898

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
3	Active Not Recruiting	Treatment	Allergic Reaction	1
Not Available	Completed	Not Available	Allergic Reaction	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Injection, solution	Subcutaneous
Solution	Intradermal; Percutaneous; Subcutaneous
Liquid	Intradermal; Percutaneous; Subcutaneous
Liquid	Intradermal; Subcutaneous	10000 unit / mL
Liquid	Intradermal; Subcutaneous	100000 unit / mL
Liquid	Intradermal; Percutaneous; Subcutaneous	100000 unit / mL
Liquid	Subcutaneous
Kit	Sublingual
Tablet	Sublingual	100 [IR]
Tablet	Sublingual	300 [IR]
Tablet, orally disintegrating	Sublingual
Injection, solution	Percutaneous
Tablet	Sublingual
Solution	Percutaneous; Subcutaneous	100000 unit
Injection, solution	Intradermal
Injection, solution	Percutaneous; Subcutaneous
Injection, solution	Intradermal	100 [BAU]/1mL
Injection, solution	Intradermal	1000 [BAU]/1mL
Injection, solution	Percutaneous; Subcutaneous	10000 [BAU]/1mL
Injection	Cutaneous; Intradermal; Subcutaneous	100000 [BAU]/1mL
Injection, solution	Intradermal; Subcutaneous	10000 [BAU]/1mL
Injection, solution	Intradermal; Subcutaneous	100000 [BAU]/1mL
Injection, solution	Percutaneous; Subcutaneous	100000 [BAU]/1mL
Solution	Intradermal; Percutaneous; Subcutaneous	10000 [BAU]/1mL
Solution	Intradermal; Percutaneous; Subcutaneous	100000 [BAU]/1mL
Injection, solution	Subcutaneous	10000 [BAU]/1mL
Injection, solution	Subcutaneous	100000 [BAU]/1mL
Solution	Percutaneous	10000 [BAU]/1mL
Solution	Percutaneous	100000 [BAU]/1mL
Injection, solution	Intradermal; Subcutaneous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

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Drug created at December 01, 2015 20:03 / Updated at December 01, 2022 23:18