Name
Acetates
Accession Number
DBCAT000495
Description

Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.

Drugs
DrugDrug Description
OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
LinezolidAn oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
Nitrilotriacetic acidNitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Acetic acidAn antimicrobial agent used to treat susceptible infections of the external auditory canal.
TirbanibulinA tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
Pentetic acidDTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It...
Peracetic acidA liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
LefamulinA pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP).
AcetateNot Annotated
BelumosudilAn oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
ZaleplonA sedative used for short term treatment of insomnia in adults.
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
Aminooxyacetic acidA compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Oseltamivir acidNot Available
AcetamideNot Available
Phosphonoacetic AcidA simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
AsimadolineInvestigated for use/treatment in irritable bowel syndrome (IBS).
RilapladibInvestigated for use/treatment in atherosclerosis and cardiovascular disorders.
BedoradrineInvestigated for use/treatment in asthma and labor and delivery.
IndibulinInvestigated for use/treatment in solid tumors.
SenicapocInvestigated for use/treatment in anemia (sickle cell) and asthma.
AvasimibeInvestigated for use/treatment in peripheral vascular disease.
RemacemideInvestigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease.
AgomelatineAgomelatine is indicated to treat major depressive episodes in adults.
AlmorexantInvestigated for use/treatment in sleep disorders and insomnia.
R-95845R-95845 is an inhibitor of HIV-1 reverse transcriptase.
AndarineAndarine is a non-steroidal selective androgen receptor modulator.
PF-06282999Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).
ArhalofenateArhalofenate has been investigated for the treatment of Gout and Hyperuricemia.
SutezolidSutezolid has been used in trials studying the treatment of Tuberculosis.
GSK-424887Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder.
RadiprodilRadiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.
AZD-5423AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).
MK-0686MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic.
LafutidineLafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
EtofamideEtofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued .
DifenpiramideNot Annotated
ClefamideNot Annotated
Edetate calcium disodium anhydrousA chelating agent used to treat lead poisoning.
LinrodostatLinrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
OlorofimOlorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
ACT-709478ACT-709478 is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
Indium In-111 satumomab pendetideFor diagnosis of extrahepatic malignant cancers
GadodiamideA gadolinium-based contrast agent used for the visualization of lesions with vascularity during magnetic resonance imaging (MRI) scans.
FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
Gadopentetic acidA gadolinium compound used as a contrast agent in MRIs.
Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Adenosine Phosphonoacetic AcidNot Available
Glycolic acidNot Available
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
Tienilic acidFor the treatment of hypertension.
ErdosteineA mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).
DP-b99Investigated for use/treatment in strokes and traumatic brain injuries.
LacosamideAn antiepileptic drug used to treat partial onset seizures in adults.
MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
1-Naphthoxyacetic acidNot Available
Dichloroacetic acidDichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms....
Gadoxetic acidA gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver.
ClinofibrateClinofibrate is a fibrate drug sold and marketed in Japan.
PiracetamA nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
IproclozideFor the treatment of depression.
Sodium acetateA compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy.
TrichloroacetateTrichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it...
LesinuradA uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
EtiracetamEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
PentetreotideA somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours.
Sodium feredetateNot Annotated
MazaticolNot Annotated
MeclofenoxateNot Annotated
Zinc acetateA medication used to treat zinc deficiency.
Potassium acetateA medication used to treat hypokalemia.
Thioglycolic acidThioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light).
Drugs & Drug Targets
DrugTargetType
OseltamivirNeuraminidasetarget
OseltamivirSialidase-1target
OseltamivirSialidase-2target
OseltamivirMultidrug resistance-associated protein 4transporter
OseltamivirSolute carrier family 15 member 1transporter
OseltamivirSolute carrier family 22 member 8transporter
OseltamivirLiver carboxylesterase 1enzyme
Linezolid23S ribosomal RNAtarget
LinezolidAmine oxidase [flavin-containing] Aenzyme
LinezolidAmine oxidase [flavin-containing] Benzyme
LinezolidSerum albumincarrier
LinezolidSolute carrier family 22 member 6transporter
LinezolidSolute carrier family 22 member 8transporter
Nitrilotriacetic acidLactotransferrintarget
Acetic acidSolute carrier organic anion transporter family member 2B1transporter
Acetic acidMonocarboxylate transporter 1transporter
TirbanibulinProto-oncogene tyrosine-protein kinase Srctarget
TirbanibulinTubulin beta chaintarget
TirbanibulinCytochrome P450 3A4enzyme
TirbanibulinCytochrome P450 2C8enzyme
TirbanibulinCytochrome P450 1A2enzyme
TirbanibulinCytochrome P450 2B6enzyme
TirbanibulinCytochrome P450 2C9enzyme
TirbanibulinCytochrome P450 2C19enzyme
TirbanibulinCytochrome P450 2D6enzyme
TirbanibulinMultidrug and toxin extrusion protein 1transporter
TirbanibulinMultidrug and toxin extrusion protein 2transporter
TirbanibulinSolute carrier organic anion transporter family member 1B1transporter
TirbanibulinSolute carrier organic anion transporter family member 1B3transporter
TirbanibulinSolute carrier family 22 member 1transporter
TirbanibulinSolute carrier family 22 member 2transporter
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
SelexipagProstacyclin receptortarget
SelexipagLiver carboxylesterase 1enzyme
SelexipagCytochrome P450 2C8enzyme
SelexipagCytochrome P450 3A4enzyme
SelexipagSolute carrier organic anion transporter family member 1B1transporter
SelexipagSolute carrier organic anion transporter family member 1B3transporter
SelexipagP-glycoprotein 1transporter
Pentetic acidTransuranium elementstarget
Pentetic acidAlpha-1-antitrypsincarrier
LefamulinCytochrome P450 3A4enzyme
Lefamulin50S ribosomal protein L22target
LefamulinP-glycoprotein 1transporter
BelumosudilRho-associated protein kinase 2target
BelumosudilSerum albumincarrier
BelumosudilAlpha-1-acid glycoprotein 1carrier
BelumosudilRho-associated protein kinase 1target
BelumosudilCytochrome P450 3A4enzyme
BelumosudilCytochrome P450 2C8enzyme
BelumosudilCytochrome P450 2D6enzyme
BelumosudilUDP-glucuronosyltransferase 1-9enzyme
BelumosudilCytochrome P450 1A2enzyme
BelumosudilCytochrome P450 2C19enzyme
BelumosudilUDP-glucuronosyltransferase 1-1enzyme
BelumosudilP-glycoprotein 1transporter
BelumosudilATP-binding cassette sub-family G member 2transporter
BelumosudilSolute carrier organic anion transporter family member 1B1transporter
ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
ZaleplonCytochrome P450 3A4enzyme
ZaleplonAldehyde oxidaseenzyme
ZaleplonCytochrome P450 3A5enzyme
ZaleplonCytochrome P450 3A7enzyme
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
Aminooxyacetic acidSerine--pyruvate aminotransferasetarget
Oseltamivir acidNeuraminidasetarget
AcetamideAliphatic amidase expression-regulating proteintarget
Phosphonoacetic AcidAlkaline phosphatasetarget
AsimadolineKappa-type opioid receptortarget
RilapladibPlatelet-activating factor acetylhydrolasetarget
BedoradrineBeta-2 adrenergic receptortarget
AvasimibeLiver carboxylesterase 1target
AvasimibeCytochrome P450 3A4enzyme
AvasimibeCytochrome P450 2C9enzyme
AvasimibeCytochrome P450 1A2enzyme
AvasimibeCytochrome P450 2C19enzyme
RemacemideCytochrome P450 3A4enzyme
Agomelatine5-hydroxytryptamine receptor 2Ctarget
AgomelatineMelatonin receptor type 1Btarget
AgomelatineMelatonin receptor type 1Atarget
AgomelatineCytochrome P450 2C9enzyme
AgomelatineCytochrome P450 1A2enzyme
R-95845Gag-Pol polyproteintarget
R-95845Gag-Pol polyproteintarget
AndarineAndrogen receptortarget
ArhalofenatePeroxisome proliferator-activated receptor gammatarget
Edetate calcium disodium anhydrousManganese cationtarget
Edetate calcium disodium anhydrousIrontarget
Edetate calcium disodium anhydrousLeadtarget
Edetate calcium disodium anhydrousAdenosine deaminaseenzyme
Edetate calcium disodium anhydrousSerum paraoxonase/lactonase 3enzyme
Edetate calcium disodium anhydrousCytochrome P450 19A1enzyme
Edetate calcium disodium anhydrousCytochrome P450 3A4enzyme
Edetate calcium disodium anhydrousSerum paraoxonase/arylesterase 1enzyme
Indium In-111 satumomab pendetideTumor-associated glycoprotein 72 (TAG-72)target
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetSolute carrier family 22 member 6transporter
FoscarnetMonocarboxylate transporter 1transporter
Gadopentetic acid6-phosphogluconate dehydrogenase, decarboxylatingtarget
Etacrynic acidSolute carrier family 12 member 1target
Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
Etacrynic acidGlutathione S-transferase A2enzyme
Etacrynic acidSerum albumincarrier
Etacrynic acidSolute carrier family 22 member 6transporter
Etacrynic acidLymphoid enhancer-binding factor 1target
Etacrynic acidGlutathione S-transferase Ptarget
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
Adenosine Phosphonoacetic AcidNucleoside diphosphate kinase Atarget
Glycolic acidGlucose-6-phosphate 1-dehydrogenasetarget
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
Tienilic acidCytochrome P450 2C9enzyme
ErdosteineAdenosine deaminaseenzyme
LacosamideSodium channel protein type 9 subunit alphatarget
LacosamideSodium channel protein type 3 subunit alphatarget
LacosamideSodium channel protein type 10 subunit alphatarget
LacosamideCytochrome P450 2C19enzyme
LacosamideCytochrome P450 2C9enzyme
LacosamideCytochrome P450 3A4enzyme
MangafodipirAlpha-2-macroglobulincarrier
MangafodipirSerum albumincarrier
MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
MangafodipirNatural resistance-associated macrophage protein 2transporter
1-Naphthoxyacetic acidGag-Pol polyproteintarget
1-Naphthoxyacetic acidGag-Pol polyproteintarget
Dichloroacetic acid[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrialtarget
Dichloroacetic acidMaleylacetoacetate isomerasetarget
Gadoxetic acidSolute carrier organic anion transporter family member 1B1transporter
Gadoxetic acidSolute carrier organic anion transporter family member 1B3transporter
Gadoxetic acidCanalicular multispecific organic anion transporter 2transporter
Gadoxetic acidCanalicular multispecific organic anion transporter 1transporter
Gadoxetic acidMultidrug resistance-associated protein 4transporter
ClinofibratePeroxisome proliferator-activated receptor alphatarget
ClinofibratePeroxisome proliferator-activated receptor gammatarget
ClinofibratePeroxisome proliferator-activated receptor deltatarget
Sodium acetateAcetyl-coenzyme A synthetase, cytoplasmicenzyme
LesinuradSolute carrier family 22 member 12target
LesinuradSolute carrier family 22 member 11target
LesinuradCytochrome P450 2C9enzyme
LesinuradCytochrome P450 3A4enzyme
Zinc acetateB1 bradykinin receptortarget
Zinc acetateMethylated-DNA--protein-cysteine methyltransferasetarget
Zinc acetateFructose-bisphosphate aldolase Atarget
Zinc acetateElongation factor 1-alpha 1target
Zinc acetateAlpha-enolasetarget
Zinc acetateGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
Zinc acetateNucleoside diphosphate kinase Atarget
Zinc acetateProtein disulfide-isomerasetarget
Zinc acetateProtein disulfide-isomerase A3target
Zinc acetatePeroxiredoxin-1target
Zinc acetatePhosphoserine phosphatasetarget
Zinc acetateTriosephosphate isomerasetarget
Zinc acetateElongation factor Tu, mitochondrialtarget
Zinc acetateEstrogen receptor alphatarget
Zinc acetateInterleukin-3target
Zinc acetateMetallothionein-2target
Zinc acetateCopper chaperone for superoxide dismutasetarget
Zinc acetateHistone deacetylase 1target
Zinc acetateHistone deacetylase 4target
Zinc acetateDNA-3-methyladenine glycosylasetarget
Zinc acetateSemenogelin-1target
Zinc acetateSuperoxide dismutase [Cu-Zn]target
Zinc acetateHistone deacetylase 8target
Zinc acetateApoptosis regulatory protein Sivatarget
Zinc acetateGlycine receptor subunit alpha-1target
Zinc acetateE3 ubiquitin-protein ligase Mdm2target
Zinc acetateInsulintarget
Zinc acetateUtrophintarget
Zinc acetateAspartoacylasetarget
Zinc acetateProtein S100-A8target
Zinc acetateProtein S100-A9target
Zinc acetateMatrix metalloproteinase-9target
Zinc acetateTumor protein p73target
Zinc acetateProtein S100-A2target
Zinc acetateCellular tumor antigen p53target
Zinc acetateMetallothionein-3target
Zinc acetateProgrammed cell death protein 6target
Zinc acetateDAN domain family member 5target
Zinc acetateMetallothionein-1Atarget
Zinc acetateAlpha-1B-glycoproteintarget
Zinc acetateAlpha-2-macroglobulintarget
Zinc acetateAngiotensinogentarget
Zinc acetateAlpha-2-HS-glycoproteintarget
Zinc acetateSerum amyloid P-componenttarget
Zinc acetateApolipoprotein A-Itarget
Zinc acetateApolipoprotein A-IItarget
Zinc acetateApolipoprotein A-IVtarget
Zinc acetateApolipoprotein B receptortarget
Zinc acetateApolipoprotein Etarget
Zinc acetateApolipoprotein L1target
Zinc acetateComplement C1q subcomponent subunit Btarget
Zinc acetateComplement C1q subcomponent subunit Ctarget
Zinc acetateComplement C1r subcomponenttarget
Zinc acetateComplement C1s subcomponenttarget
Zinc acetateComplement C3target
Zinc acetateComplement C4-Btarget
Zinc acetateC4b-binding protein alpha chaintarget
Zinc acetateC4b-binding protein beta chaintarget
Zinc acetateComplement C5target
Zinc acetateLys-63-specific deubiquitinase BRCC36target
Zinc acetateComplement component C8 alpha chaintarget
Zinc acetateComplement component C8 beta chaintarget
Zinc acetateComplement component C8 gamma chaintarget
Zinc acetateComplement factor Btarget
Zinc acetateComplement factor Htarget
Zinc acetateComplement factor Itarget
Zinc acetateClusterintarget
Zinc acetateCeruloplasmintarget
Zinc acetateCarboxypeptidase N catalytic chaintarget
Zinc acetateCarboxypeptidase N subunit 2target
Zinc acetateDermcidintarget
Zinc acetateDesmoplakintarget
Zinc acetateCoagulation factor XIItarget
Zinc acetateCoagulation factor XIII B chaintarget
Zinc acetateProthrombintarget
Zinc acetateFicolin-3target
Zinc acetateFibrinogen alpha chaintarget
Zinc acetateFibronectintarget
Zinc acetateGelsolintarget
Zinc acetateHemoglobin subunit alphatarget
Zinc acetateHemoglobin subunit betatarget
Zinc acetateHaptoglobin-related proteintarget
Zinc acetateHornerintarget
Zinc acetateInsulin-like growth factor-binding protein complex acid labile subunittarget
Zinc acetateIg alpha-1 chain C regiontarget
Zinc acetateIg mu chain C regiontarget
Zinc acetateImmunoglobulin kappa variable 1-17target
Zinc acetateIg kappa chain V-III region GOLtarget
Zinc acetateImmunoglobulin lambda variable 3-21target
Zinc acetateInter-alpha-trypsin inhibitor heavy chain H1target
Zinc acetateInter-alpha-trypsin inhibitor heavy chain H2target
Zinc acetateInter-alpha-trypsin inhibitor heavy chain H3target
Zinc acetateInter-alpha-trypsin inhibitor heavy chain H4target
Zinc acetateImmunoglobulin J chaintarget
Zinc acetateJunction plakoglobintarget
Zinc acetatePlasma kallikreintarget
Zinc acetateKininogen-1target
Zinc acetateKeratin, type II cytoskeletal 1target
Zinc acetateKeratin, type I cytoskeletal 10target
Zinc acetateKeratin, type I cytoskeletal 14target
Zinc acetateKeratin, type I cytoskeletal 16target
Zinc acetateKeratin, type II cytoskeletal 2 epidermaltarget
Zinc acetateKeratin, type II cytoskeletal 5target
Zinc acetateKeratin, type II cytoskeletal 6Atarget
Zinc acetateKeratin, type I cytoskeletal 9target
Zinc acetateAlpha-1-acid glycoprotein 2target
Zinc acetateN-acetylmuramoyl-L-alanine amidasetarget
Zinc acetateSerum paraoxonase/arylesterase 1target
Zinc acetatePregnancy zone proteintarget
Zinc acetateProtein S100-A7target
Zinc acetateSelenoprotein Ptarget
Zinc acetateAlpha-1-antitrypsintarget
Zinc acetateAlpha-1-antichymotrypsintarget
Zinc acetateKallistatintarget
Zinc acetateCorticosteroid-binding globulintarget
Zinc acetateHeparin cofactor 2target
Zinc acetateSex hormone-binding globulintarget
Zinc acetateSerotransferrintarget
Zinc acetateTransthyretintarget
Zinc acetateVitronectintarget
Zinc acetateAmyloid-like protein 1target
Zinc acetateAmyloid-like protein 2target
Zinc acetateAmyloid beta A4 proteintarget
Zinc acetatePoly [ADP-ribose] polymerase 1target
Zinc acetateCarbonic anhydrase 1enzyme
Zinc acetateCarboxypeptidase Eenzyme
Zinc acetateAlcohol dehydrogenase 1Cenzyme
Zinc acetateInsulin-degrading enzymeenzyme
Zinc acetateSuperoxide dismutase [Cu-Zn]enzyme
Potassium acetateSodium/potassium-transporting ATPase subunit alpha-1target