- Accession Number
Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
- ATC Classification
Drug Drug Description Albendazole A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. Piperazine A medication used to treat roundworm and pinworm. Mebendazole A benzimidazole anthelmintic used to treat helminth infections. Diethylcarbamazine An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa. Thiabendazole A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. Levamisole Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections. Praziquantel An anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis. Oxamniquine For treatment of Schistosomiasis caused by Schistosoma mansoni Bithionol Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... Niclosamide An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children. Pyrvinium An anthelmintic agent used for the treatment of pinworm infestations. Flubendazole Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe. Pyrantel An anthelmintic used to treat helminth infections. Fenbendazole Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,... Metrifonate Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. Triclabendazole An anthelmintic drug used to treat fascioliasis. Dichlorophen Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from... Niridazole Not Annotated Oxantel An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections. Oxibendazole Investigated for use/treatment in infectious and parasitic disease (unspecified) and pediatric indications. Hexylresorcinol An ingredient used to relieve irritation, pain, and prevent infection. Cambendazole Not Annotated Clorsulon Not Annotated Coumaphos This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a... Dichlorvos Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products... Doramectin Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in... Eprinomectin Not Annotated Febantel Not Annotated Moxidectin Moxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and... Oxfendazole Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. Bunamidine Bunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations. Dithiazanine Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was... Hygromycin B Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. Milbemycin oxime Not Annotated Oltipraz Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease. Carbendazim Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific. Albendazole oxide Not Annotated Stibophen Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. Bephenium Not Annotated Ciclobendazole Not Annotated Desaspidin Not Annotated Ivermectin An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. Lucanthone Intended for use as a radiation sensitizer in the treatment of brain cancer. Benzimidazole Not Available Hycanthone Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used. Artesunate Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. Antimony potassium tartrate Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects. Plumbagin Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
- Drugs & Drug Targets