Leuprolide | A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty. |
Sermorelin | For the treatment of dwarfism, prevention of HIV-induced weight loss |
Goserelin | A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. |
Salmon calcitonin | A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. |
Desmopressin | A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. |
Cetrorelix | A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. |
Vasopressin | A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. |
Felypressin | For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. |
Pentagastrin | A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors. |
Gonadorelin | A synthetic GnRH used to test the function of gonadotropes and the pituitary. |
Nafarelin | A gonadotropin releasing hormone agonist used to treat central precocious puberty. |
Aminolevulinic acid | A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. |
Tetracosactide | A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. |
Corticotropin | A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. |
Terlipressin | Commonly used to stop bleeding of varices in the food pipe (oesophagus). |
Vapreotide | For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. |
Nesiritide | A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. |
G17DT | Intended for the treatment of various forms of cancer. |
Dirucotide | For the treatment of multiple sclerosis (MS). |
CR665 | Investigated for use/treatment in pain (acute or chronic). |
Ciliary neurotrophic factor | Investigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified). |
Corticorelin | Investigated for use/treatment in brain cancer and neurologic disorders. |
Icatibant | A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). |
Aviptadil | Not Annotated |
Calcitonin gene-related peptide | Investigated for use/treatment in myocardial infarction, heart disease, and asthma. |
Labradimil | Investigated for use/treatment in brain cancer and pediatric indications. |
Pasireotide | A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. |
Buserelin | A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. |
Saralasin | Not Annotated |
Ganirelix | A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. |
Histrelin | A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. |
Lanreotide | A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. |
Triptorelin | A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. |
DADLE | A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate. |
DPDPE | A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. |
Tesamorelin | A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. |
Corticorelin ovine triflutate | A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. |
Somatostatin | A naturally-occurring peptide hormone used for the symptomatic treatment of acute bleeding from esophageal varices. |
Polaprezinc | Peptic ulcer disease, dyspepsia . |
Protirelin | A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. |
Secretin porcine | A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. |
Deslorelin | Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. |
Bremelanotide | Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... |
Carnosine | Carnosine has been investigated for the treatment of Gulf War Illness. |
Setmelanotide | Setmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies. |
Bombesin | Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... |
Neuropeptide Y | Neuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus. |
Angiotensin II | A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. |
TAK-448 | TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism. |
TT-232 | Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). |
Bradykinin | Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. |
Selepressin | Selepressin has been used in trials studying the treatment of Septic Shock. |
Pentetreotide | Pentetreotide has been used in trials studying the diagnostic of cushing syndrome. |
Nerve Growth Factor | Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others. |
Tiplimotide | Tiplimotide has been used in trials studying the treatment of Multiple Sclerosis. |
Zoptarelin doxorubicin | Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. |
Somatoprim | Somatoprim is under investigation for the treatment of Acromegaly. |
Pancreatic Polypeptide | Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. |
Urocortin-2 | Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. |
Alsactide | Not Annotated |
Ornipressin | Not Annotated |
Angiotensinamide | Not Annotated |
Elcatonin | Not Annotated |
Secretin human | A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. |
Lypressin | Not Annotated |
Indium In-111 pentetreotide | Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. |
Sar9, Met (O2)11-Substance P | Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection. |
Gastric inhibitory polypeptide | Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). |
Contulakin-G | Investigated for use/treatment in pain (acute or chronic). |
Angiotensin 1-7 | TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. |
Aclerastide | Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. |
Tirzepatide | Tirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes). |
Dopastatin | Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). |
Dynorphin | Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1). |
Kisspeptin-10 | Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men). |