Gastro-esophageal Reflux Disease (GERD) (DBCOND0077290)

Identifiers

Synonyms
Reflux Disease, Gastro-Esophageal / Oesophageal Reflux / Gastroesophageal Refluxdisease / Gastrooesophageal reflux disease / Gastro-esophageal Reflux Disease / GERD / Esophageal Reflux / Gastroesophageal Reflux Disease (GERD) / Gastro Oesophageal Reflux Disease / Gastro-esophageal Reflux Diseases / GERD (Gastroesophageal Reflux Disease) / Gastro-Oesophageal Reflux Disease / GERD - Gastro-Esophageal Reflux Disease / GERD Gastroesophageal Reflux Disease / Gastroesophageal Reflux Disease / Gastro Esophageal Reflux Disease / Gastrooesophageal reflux / Gastroesophageal reflux / Acid reflux (finding) / GORD / Gastro-esophageal reflux disease without esophagitis / Gastroesophageal reflux disease (disorder) / Esophageal reflux finding (finding)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Alginic acid
Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .
No drug targets
Cimetidine
A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
Cinitapride
A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
Dexrabeprazole
A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
Dimethicone
An ingredient used to treat dry and irritated eyes.
No drug targets
Domperidone
A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
Esomeprazole
A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
Etodolac
An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Famotidine
A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
Nizatidine
An H2 receptor antagonist used to treat GERD and a variety of ulcers.
Omeprazole
A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
Pantoprazole
A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
Potassium bicarbonate
An ingredient used as an antacid or to treat hypokalemia.
Rabeprazole
A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Ranitidine
A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
Sodium bicarbonate
A compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
Sucralfate
A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05579587
Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06170060
Treatment of Reflux With Sleeve GastrectomyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05214079
Determination of the Left Paratrachéal Force Required to Occlude the Esophageal EntranceNo drug interventionspreventionNot Availableunknown_status
NCT03835663
The Bacterial Composition of the Stomach in Reflux DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05060744
Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal RefluxNo drug interventionstreatmentNot Availablerecruiting
NCT00363701
Study of Long-Term Use of Proton-Pump-Inhibitors in General Practicetreatment4unknown_status
NCT02619747
Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patientsother3terminated
NCT02471989
FODMAPs and Refractory GERDNo drug interventionsotherNot Availablecompleted
NCT02812407
HRIM vs Mucosal Impedance in GERD ParticipantsNo drug interventionsdiagnosticNot Availablewithdrawn
NCT02623062
Compound Sodium Alginate Oral Suspension Sachet Symptomatic Relief Studytreatment3completed
NCT04988347
Spirulina Platensis for PPI Withdrawaltreatment2completed
NCT03788109
Relationship Between Gastric Accommodation, TLESRs and Reflux in HV and in GERD With or Without Overlapping DyspepsiaNo drug interventionsbasic_scienceNot Availablecompleted
NCT02114216
Nociceptors, Neurotrophic Factors and Cytokine Expression in Gastroesophageal Reflux DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT03824548
Outcomes for Patients With Gastro-Esophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT05296655
Kazakh Version of Reflux Symptom IndexNo drug interventionsNot AvailableNot Availablecompleted
NCT04884074
Effect of Routine Anterior Crural Repair in De-Novo Gastroesophageal Reflux After Laparoscopic Sleeve GastrectomyNo drug interventionspreventionNot Availablerecruiting
NCT05678491
Endoscopic Treatment of Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT03322553
Endoscopic Full Thickness Plication (GERD-X) for the Treatment of PPI Dependent GERD:No drug interventionstreatmentNot Availablecompleted
NCT01788085
Development of Applications of the Bravo® pH Monitoring System and Evaluation of Its Performance (Encore)No drug interventionsdiagnosticNot Availablewithdrawn
NCT01867931
Epithelial Damage in GERDNo drug interventionsNot AvailableNot Availablecompleted
NCT03596476
Diagnostic Yield of Post PRandial Esophageal High Resolution Impedance Manometry in Patients With Gastro-Esophageal Reflux Disease Symptoms Resistant to Proton Pump Inhibitor TherapyNo drug interventionsdiagnosticNot Availablerecruiting
NCT01560910
Detection of Minimal Change Esophagitis by I-scanNo drug interventionsNot AvailableNot Availablecompleted
NCT02456779
Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERDNo drug interventionsNot AvailableNot Availablecompleted
NCT06564558
The Effect of Postural Correction On Gastroesophageal Reflux DiseaseNo drug interventionsotherNot Availablerecruiting
NCT01503476
Development of Applications of the Bravo® pH Monitoring System and Evaluation of Its PerformanceNo drug interventionsdiagnostic4completed
NCT02437682
Translation and Validation of the PASS Test for GERD Patients With Partial Response to PPI: PASS-HKNo drug interventionsNot AvailableNot Availableunknown_status
NCT01306799
To Learn How Bone Structure and Bone Mass Change After Long-term PPI UseNo drug interventionsNot AvailableNot Availablecompleted
NCT06641375
Anti-Reflux Endoscopic Therapy Using Argon Plasma Coagulation (AREA) in Gastroesophageal Reflux Disease (GERD) Patients: A Single Center, Randomized, Sham, Controlled Trial (The AREA Study)No drug interventionstreatmentNot Availablerecruiting
NCT02441400
EndoStim Patient RegistryNo drug interventionsNot AvailableNot Availableterminated
NCT03886961
The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant RecipientsNo drug interventionspreventionNot Availablerecruiting
NCT04699591
Compassionate Use of Domperidone for Refractory GastroparesistreatmentNot Availablerecruiting
NCT04795934
Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia RepairNo drug interventionsotherNot Availableactive_not_recruiting
NCT05974722
Mesh Vs Pledgets for Repair of Paraesophageal HerniaNo drug interventionspreventionNot Availablerecruiting
NCT05696184
Mechanisms Preventing Pharyngeal RefluxNo drug interventionsdiagnosticNot Availablerecruiting
NCT02226484
Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD?basic_science1completed
NCT01397084
To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazoletreatment4completed
NCT01601379
Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease.No drug interventionsNot AvailableNot Availablecompleted
NCT01887743
Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Studybasic_science1completed
NCT05833243
Effectiveness of Modified Diaphragmatic Training for Gastroesophageal Reflux Disease Post Covid-19No drug interventionstreatmentNot Availablecompleted
NCT05469854
A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan GlurateNo drug interventionsbasic_science1recruiting
NCT03488147
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgerytreatment2withdrawn
NCT04771247
Endoscopic Cardiac Band Ligation for the Management of Refractory GERD After Laparoscopic Sleeve GastrectomyNo drug interventionstreatmentNot Availablewithdrawn
NCT03363698
MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic CoughNo drug interventionsNot AvailableNot Availablecompleted
NCT02142998
A Prospective Blinded Randomized Study Comparing Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-y Gastric Bypass and Their Effect on Gastro-Esophageal Reflux Disease Using 24 Horus pH MonitoringNo drug interventionsotherNot Availablesuspended
NCT04422405
Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGBNo drug interventionstreatmentNot Availablerecruiting
NCT00545883
Impact of GERD on Daily Life (NIS)No drug interventionsNot AvailableNot Availablecompleted
NCT06241183
Famotidine and Antacids for Treatment of Dyspepsiatreatment4recruiting
NCT01509261
Efficacy Study of Ilaprazole to Treat Erosive Esophgitistreatment3completed
NCT00536328
What is the Predictive Value of the Reflux Impact ScaleNo drug interventionsNot AvailableNot Availableterminated
NCT00573911
Acid Reflux and Stromal Fibroblasts in Barrett's EsophagusNo drug interventionsdiagnostic1completed
NCT04255693
Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet AdherenceNo drug interventionsotherNot Availablerecruiting
NCT02395471
Cytosponge Adequacy Study Evaluation IINo drug interventionsdiagnosticNot Availablecompleted
NCT04759378
Comorbid Esophageal Disorders in IBS PatientsNo drug interventionsscreeningNot Availableunknown_status
NCT03357809
Endoscopic Resection in Gastro-Esophageal Reflux DiseaseNo drug interventionstreatmentNot Availablesuspended
NCT00256737
Sopran - Omeprazole Treatment Versus Surgerytreatment3completed
NCT05131932
Ablation of Esophageal Inlet Patches in Patients Referred for Bravo pH-TestingNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04626232
Comparison of the Sleeve Gastrectomy Technique With a Nissen Fundoplication Added to the Conventional Sleeve Gastrectomy Technique in Morbidly Obese PatientsNo drug interventionsotherNot Availableterminated
NCT04360252
Gracie Diet for Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT01710800
Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor TherapydiagnosticNot Availablecompleted
NCT00584259
Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of RefluxNo drug interventionssupportive_careNot Availablecompleted
NCT00586859
Multi-Center Study of the NDO Surgical Plicator Utilizing Multiple Implants for the Treatment of GERDNo drug interventionstreatmentNot Availableterminated
NCT02210975
An Investigation of Electrical Stimulation on Gastroesophageal Reflux Disease (GERD) in Patients After Sleeve GastrectomyNo drug interventionstreatmentNot Availableunknown_status
NCT00444275
Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patientstreatment4completed
NCT04229342
Post-POEM GERD in Patients Undergoing Conventional Versus Oblique Fibers Sparing Posterior Myotomy for Achalasia CardiaNo drug interventionstreatmentNot Availablecompleted
NCT02922699
Efficacy and Saafety of Omez Iin Patients With H.Pylori Associated Diseasestreatment4completed
NCT01624506
Observational Study of Anti-Reflux SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT05210049
Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in VeteransNo drug interventionsscreeningNot Availablerecruiting
NCT04652336
Study Comparing the Effect of Ligamentum Teres Cardiopexy on de Novo GERD Post LSGNo drug interventionstreatmentNot Availableunknown_status
NCT02637713
Management of Reflux After Sleeve Using StrettaNo drug interventionstreatmentNot Availableterminated
NCT03985319
Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)treatment1completed
NCT00567619
LIFE NIS, GERD-Patients - Evaluation of Burden of Disease Determined by GERD Impact Scale (GIS)No drug interventionsNot AvailableNot Availablecompleted
NCT01556919
Esophageal Monitoring Device for Assessing Mucosal ImpedanceNo drug interventionsNot AvailableNot Availablecompleted
NCT00336219
Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343)treatment3completed
NCT05080634
Analysis of Prevalence and Risk Factors Associated With Gastroesophageal Reflux Disease and Esophagitis After Peroral Endoscopic MyotomyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06457334
Effect of Helicobacter Pylori Eradication on Gastroesophageal RefIux Disease (GERD)No drug interventionsNot AvailableNot Availablerecruiting
NCT02514616
Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (GERD)No drug interventionstreatmentNot Availableterminated
NCT03705416
Long Term Outcomes of Bariatric Patients Treated With Surgery or EndoscopyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00161096
On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medicationtreatment3unknown_status
NCT00321958
Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal CancerNo drug interventionsNot AvailableNot Availableterminated
NCT04248335
Effect of Obesity on Proton Pump Inhibitorstreatment4recruiting
NCT02028663
Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitistreatment2completed
NCT00229086
Gatekeeper European 005No drug interventionsNot AvailableNot Availableterminated
NCT04301986
Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's EsophagusNo drug interventionsotherNot Availablecompleted
NCT03558425
A Study to Compare PK, PD and Safety of CKD-381 and D026 in Healthy SubjectsNo drug interventionstreatment1completed
NCT04830930
A Study to Investigate the Effect of Food on the PK, PD of CKD-381 in Healthy VolunteersNo drug interventionstreatment1completed
NCT02429830
LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve GastrectomyNo drug interventionstreatmentNot Availablecompleted
NCT00354757
CYP2C19 Genetic Polymorphism on the Accuracy of Proton-Pump Inhibitor Testingdiagnostic4completed
NCT03859557
The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps BiopsyNo drug interventionsNot AvailableNot Availablecompleted
NCT00513331
Barrett's Esophagus & Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03824431
High Definition Endoscopy With NBI. Contribution in Patients With Non-erosive EsophagitisNo drug interventionsNot AvailableNot Availablecompleted
NCT02140073
Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severitytreatment4unknown_status
NCT01574573
Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective StudyNo drug interventionstreatmentNot Availableterminated
NCT02227927
Treatment Use of Domperidone for GastroparesisNot AvailableNot Availabletemporarily_not_available
NCT04202276
The Study of Nutrition of Children and Adolescents With GERDNo drug interventionsdiagnosticNot Availablecompleted
NCT05851794
Intraoperative Endomanometric Laparoscopic Nissen Fundoplication Improves Postoperative OutcomesNo drug interventionstreatmentNot Availablecompleted
NCT02759094
Evaluation of Safety and Effectiveness of the RefluxStop Device in the Management of GERDNo drug interventionstreatmentNot Availableunknown_status
NCT03747991
How Reflux Medications Affect the Microbiome of InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT00287391
Sleep Disorders and Gastroesophageal Reflux Disease (GERD)treatment4completed
NCT03735862
Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESHNo drug interventionsNot AvailableNot Availablecompleted
NCT01202929
Correlation of High Resolution Esophageal Manometry With SymptomsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04901429
Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric BypassNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00222989
PPI Versus Placebo in Severe Functional HeartburnNo drug interventionstreatmentNot Availablewithdrawn
NCT00597792
Registry Study of the NDO Surgical Plicator for the Treatment of GERDNo drug interventionstreatmentNot Availableterminated
NCT04252144
Study of Dietary Patterns and Food Diversity in Russian GERD PatientsNo drug interventionspreventionNot Availableunknown_status
NCT00241540
Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDstreatment3completed
NCT01799967
Minimally Invasive Surgery of the Gastro-esophageal JunctionNo drug interventionsNot AvailableNot Availablerecruiting
NCT01707901
A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Diseasetreatment1completed
NCT06159972
Can EndoFLIP Improve Quality of Life Before and After Fundoplication?No drug interventionstreatmentNot Availablerecruiting
NCT05719168
Gastric Neuromuscular Function in GERDNo drug interventionsdiagnosticNot Availablerecruiting
NCT00318968
Nexium RESPONSE Trialdiagnostic4completed
NCT03536169
Utilization of Anti-reflux Treatment and Course of Illness Leading to ReoperationNo drug interventionsNot AvailableNot Availablecompleted
NCT04846010
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2No drug interventionstreatment1 / 2unknown_status
NCT02935881
STRETTA ,Radio Frequency Ablation (RFA) v/s Sham Therapy for the Treatment of Refractory GERDNo drug interventionstreatment3unknown_status
NCT02629081
Image-Enhanced Endoscopy (IEE) for Diagnosis of Non-Erosive Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01551095
Self-Propelled Percutaneous Endoscopic GastroJejunostomy (PEG-J)No drug interventionssupportive_care2terminated
NCT00635414
Open, Randomized, Two Way Crossover 40mg, Orally and Intravenouslytreatment4completed
NCT01386255
Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsytreatment4withdrawn
NCT01265550
A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitorstreatment3completed
NCT01194323
Biology in Patients With Reflux EsophagitisNo drug interventionsNot AvailableNot Availablecompleted
NCT04294823
Sensitivity and Specificity of the Modified Helicobacter Test INFAINot AvailableNot Availablewithdrawn
NCT00697008
Asociación Española de Gastroenterologia (Spanish Gastroenterology Association) Gastroesophageal Reflux Disease Guideline - Prospective StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00695838
National Survey on Gastroesophageal Reflux Disease (GERD) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00629564
An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)treatment4completed
NCT03999502
Endomina Suturing Device as a Treatment of GERD.No drug interventionstreatmentNot Availableunknown_status
NCT00737802
In Vivo Anatomy, Physiology, Mechanics and Function of the Lower Esophageal SphincterNo drug interventionsNot AvailableNot Availableterminated
NCT03444402
A Study to Compare PK and Safety of CKD-381 and D026 in Healthy Male Subjectstreatment1completed
NCT00318084
PPI Test in GP Patientstreatment4completed
NCT05742984
Investigate Linaprazan Glurate/Linaprazan in Healthy SubjectsNo drug interventionstreatment1active_not_recruiting
NCT01079884
Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performancehealth_services_researchNot Availablecompleted
NCT00378287
A Study to Monitor Intragastric pH in Patients Taking Rabeprazole vs. Patients Taking Pantoprazoletreatment1completed
NCT02762487
RELIEF Europe StudyNo drug interventionstreatmentNot Availableterminated
NCT02575287
Minimal Injuries From Esophagus Detected by Optical Enhancement System™ Associated to Optical Magnification HD ScopesNo drug interventionsNot AvailableNot Availablecompleted
NCT04828733
One Anastomosis Gastric Bypass With Excluded Stomach Fundoplication: FundoRing vs Nissen vs OAGB Without FundoplicationNo drug interventionstreatmentNot Availablecompleted
NCT00761254
Domperidone for Relief of Gastrointestinal DisorderstreatmentNot Availableterminated
NCT04282954
Clinical Trial to Evaluate the Safety and Efficacy of JP-1366 in Patients With Erosive Gastroesophageal Reflux Diseasetreatment2completed
NCT00524251
The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux PatientsNot AvailableNot Availablecompleted
NCT00388453
Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT06141577
A Study to Compare Pharmacokinetics, Pharmacodynamics and Safety of UI059 and UIC202201 in Healthy SubjectsNo drug interventionstreatment1completed
NCT03558477
PK/PD Clinical Trial of YYD601 in Healthy Adult Maletreatment1completed
NCT05781347
Stretta Versus Conservative Treatment in Obese and Non-obeseNo drug interventionstreatmentNot Availablerecruiting
NCT02972047
Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal RefluxNo drug interventionstreatmentNot Availablecompleted
NCT00884247
Structured Treatment of Gastroesophageal Reflux in a Company Health Care Setting, -Effect on Quality of Life, Symptoms and ProductivityNo drug interventionsNot AvailableNot Availablecompleted
NCT00681005
A Comparative Study of Proton-pump Inhibitor Tests for Chinese Reflux Patients in Relation to the CYP2C19 GenotypesdiagnosticNot Availablecompleted
NCT01899183
Surgery in Chronic Cough GERD RelatedNo drug interventionsNot AvailableNot Availablecompleted
NCT00591461
Study of Endoscopic Barrett's Esophagus DiagnosisNo drug interventionsNot AvailableNot Availableterminated
NCT05069493
Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple SuturingNo drug interventionsNot AvailableNot Availablecompleted
NCT03499171
Citalopram for Reflux Hypersensitivity and Functional Heartburntreatment4unknown_status
NCT00691171
Electronic Health Record (EHR)-Based Intervention for Gastroesophageal Reflux Disease (GERD) and Chronic Non-steroidal Anti-inflammatory Drug (NSAID) UseNo drug interventionsNot AvailableNot Availablecompleted
NCT03031288
Effects of Vented Base Feeding Bottle in Preterm Infants With GERD Symptoms.No drug interventionstreatmentNot Availablecompleted
NCT03090607
Novel Endoluminal Clinical TreAtment of RefluxNo drug interventionstreatmentNot Availableunknown_status
NCT00295685
Nexium 40mg Once Daily vs Prevacid 30mg Twice a Day for Control of Severe GERDNo drug interventionstreatment4completed
NCT00324532
to Assess the Efficacy and Safety of the Probiotic E. Coli Strain M17 on Patients With GERDNo drug interventionstreatment3completed
NCT00688675
Gastroesophageal Reflux Disease (GERD) Segmentation: Document How Swiss General Practitioners (GPs) Allocate Their GERD Patients to the Three GERD Patient SegmentsNo drug interventionsNot AvailableNot Availablecompleted
NCT04292470
Physiology of GERD and Treatment ResponsetreatmentNot Availablecompleted
NCT03355170
Cardiac Safety of Lansoprazole and Domperidon Combinationscreening4withdrawn
NCT04931706
Nissen Sleeve by Single Port With Magnetic AssistanceNo drug interventionsNot AvailableNot Availableunknown_status
NCT00242736
An Open-Label Study of Once-Daily Oral Administration of Esomeprazole 40 mg in Patients With Symptoms of Gastroesophageal Reflux Disease (GERD)treatment4completed
NCT02274636
Study of a Dietary Supplement for Reflux During SleepNo drug interventionssupportive_careNot Availableunknown_status
NCT05710913
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)No drug interventionsNot AvailableNot Availablerecruiting
NCT00703534
Validation of Patient-reported Outcomes Measures for the Assessment of Gastroesophageal Reflux Disease (GERD) SymptomsNot Available2completed
NCT00373334
Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT03329534
Gluten Related Disorders in Barrett's EsophagusNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03238534
Efficacy and Safety Evaluation of Neobianacid® in GERD and EPStreatment4completed
NCT06157424
Efficacy and Safety of Combined Thread Embedding Acupuncture With Auricular Acupuncture for GERDNo drug interventionstreatmentNot Availablecompleted
NCT00838396
A Study to Evaluate the Efficacy and Safety of Controlled Release Arbaclofen Placarbil (XP19986) in Patients With Gastroesophageal Reflux Diseasetreatment2completed
NCT00427635
Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patientstreatment3completed
NCT01260935
Comparison of Laparoscopic Hill and Laparoscopic Nissen Anti-Reflux ProceduresNo drug interventionstreatmentNot Availablecompleted
NCT00586963
Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed EsophagitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05042063
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00287339
The Utility of Nexium in Chronic Cough and Reflux Diseasetreatment4completed
NCT00261339
Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)treatment4completed
NCT00587522
Study of the NDO Endoscopic Plication System For the Treatment of Symptomatic Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04120025
Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in OutpatientsNo drug interventionstreatmentNot Availablecompleted
NCT03568825
Response Surface Pathway Design With Two Interventional- and One Response Variable in Estimating Minimum Efficacy DoseNo drug interventionsbasic_scienceNot Availablecompleted
NCT05874726
Biological Sample Repository for Gastrointestinal DisordersNo drug interventionsNot AvailableNot Availablesuspended
NCT04028466
Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Featurestreatment4terminated
NCT03600974
A New System for GERD Diagnosis and TreatmentNot AvailableNot Availableunknown_status
NCT04703374
A Study to Compare PK, PD and Safety of CKD-382 in Healthy SubjectsNo drug interventionstreatment1unknown_status
NCT03676374
Prucalopride Treatment for Refractory Gastro-esophageal Reflux Diseasetreatment4unknown_status
NCT03959020
Applying Long-term Follow-up to Improve Patient Selection in Laparoscopic Anti-reflux SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT02776982
Influence of Central Obesity on the Esophageal Epithelial BarrierNo drug interventionsdiagnosticNot Availablecompleted
NCT03574831
the Efficency and Safety of Stretta in GERDNo drug interventionsNot AvailableNot Availableunknown_status
NCT02997527
[Impedance Measurement for Non-Erosive Reflux DiseaseNo drug interventionsdiagnosticNot Availablewithdrawn
NCT05899491
Role of ARMA in Selective Subset of Refractory GERD Patients.No drug interventionstreatmentNot Availablerecruiting
NCT05089929
Endoscopic Esophageal Topography (Endoflip 2.0) Versus High-resolution Manometry (HRM)No drug interventionsNot AvailableNot Availablecompleted
NCT00317044
Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthmatreatment2completed
NCT05579444
Systems Biology of Gastrointestinal and Related DiseasesNo drug interventionsNot AvailableNot Availableterminated
NCT01230944
Conventional Nissen Fundoplication Versus Laparoscopic Nissen FundoplicationNo drug interventionstreatmentNot Availablecompleted
NCT01134367
An Epidemiological Study to Describe Symptom Control and Impact of Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02620501
Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery TimetreatmentNot Availableunknown_status
NCT04945304
9-Step Magnetic Bariatric Revisional SurgeryNo drug interventionsNot AvailableNot Availablerecruiting
NCT06084572
Prospective Evaluation of pH-impedance Tracings According to the Wingate Consensus, and Influence on GERD Classification According to the Lyon ConsensusNo drug interventionsNot AvailableNot Availablerecruiting
NCT00582972
Does Omeprazole Decrease Intestinal Calcium Absorption?Not Available4completed
NCT04243668
ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)No drug interventionstreatmentNot Availablecompleted
NCT05178446
GERD After Sleeve GastrectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT00624546
Effect of Antireflux Therapy on the Expression of Genes in Patients With GERDNot AvailableNot Availableterminated
NCT02587910
Melanole, a Dietary Supplement, for the Treatment of Gastroesophageal Reflux DiseaseNo drug interventionstreatment2 / 3unknown_status
NCT00728481
The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitistreatment2 / 3completed
NCT02278081
The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinatetreatment4unknown_status
NCT01384695
A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1screening0terminated
NCT00747695
A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusivetreatment1completed
NCT00241514
Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDstreatment3completed
NCT05282914
A Study to Compare PK, PD and Safety of UI058 and UIC202004 in Healthy SubjectsNo drug interventionstreatment1completed
NCT06126055
Endoscopic Band Ligation for Treating Reflux DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00524355
Epidemiological Study to Assess the Symptoms and Patterns of Diagnosis and Treatment of GERDNo drug interventionsNot AvailableNot Availablecompleted
NCT03079050
An Open-Label Trial of Dexlansoprazole 60mg for the Relief of Heartburn During the Fasting Month of Ramadantreatment4completed
NCT03020550
Correlates of GERD Symptom SeverityNo drug interventionsNot AvailableNot Availablecompleted
NCT00634023
Canadian, Multi-Centre Study of Symptom Burden and Clinical Management in Subjects With GERDNo drug interventionsNot AvailableNot Availablecompleted
NCT05590208
Sleeve Gastrectomy With Cruroplasty and Omental Rape for Treatment of Morbid Obesity With Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT05041608
Endoscopic Surgery for Gastrointestinal Disorders: A Multicenter Registry StudyNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05192538
A Novel Endoloop Pre-test to Treat Gastroesophageal RefluxNo drug interventionstreatmentNot Availableunknown_status
NCT02479438
Gastroesophageal Reflux Disease Prospective RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT01132638
Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Diseasetreatment3completed
NCT05108038
A Study to Evaluate the PK, PD and Safety of CKD-382 in Healthy SubjectsNo drug interventionstreatment1unknown_status
NCT03211143
A Study to Compare PK, PD and Safety of CKD-381 in Healthy Subjectstreatment1completed
NCT00222170
Rabeprazole in Subjects With Gastroesophageal Reflux Disease (GERD)treatment2completed
NCT03375060
Histology Post-Endoscopic Eradication Therapy (EET)No drug interventionsNot AvailableNot Availablecompleted
NCT03183310
The Effect of Chlorpromazine on Esophageal Sensitivity in Healthy Volunteers.otherNot Availableunknown_status
NCT00634608
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice WorkflowNo drug interventionsNot AvailableNot Availablecompleted
NCT06564246
Clinical Study Evaluating The Role of Vonoprazan Versus Pantoprazole in Patients With Gastroesophageal Reflux Diseasetreatment4recruiting
NCT00734747
Safety and Efficacy the Medigus SRS Endoscopic Stapling System in Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment3completed
NCT01091805
Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) RefluxNo drug interventionsNot AvailableNot Availablecompleted
NCT00857597
Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatmenttreatment3terminated
NCT03561883
Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)No drug interventionstreatment3completed
NCT02749071
An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of RefluxNo drug interventionstreatmentNot Availableterminated
NCT01657578
Optimal Dosing of Omeprazole in Neonatestreatment2completed
NCT00658632
Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT00587275
Safety and Efficacy of AST-120 in Patients With GERD Who Continue to be Symptomatic on a Standard Dose of PPItreatment2terminated
NCT00658775
Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT00839306
Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT04660019
Combined Scalp and Ear Acupuncture in Patients With Proton Pump Inhibitor- Dependent Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT05870163
Post-Market Registry for the Evaluation of RefluxStop in GERD TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT01327963
Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF StudyNo drug interventionstreatmentNot Availableterminated
NCT00575822
A Study to Determine the Effectiveness of Endoscopic Full-Thickness Plication for the Treatment of GERDNo drug interventionstreatmentNot Availableterminated
NCT01373125
Is the Neosquamous Epithelium "Normal" Following Endoscopic Ablation of Dysplastic Barrett's Esophagus?No drug interventionsNot AvailableNot Availablecompleted
NCT01915173
Response to Supplement and Placebo in GERDNo drug interventionstreatmentNot Availablecompleted
NCT00787891
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patientstreatment3completed
NCT00587392
Endoscopic Full-Thickness Plication for the Treatment of GERD: Long-Term Multicenter ResultsNo drug interventionsNot AvailableNot Availablecompleted
NCT00241501
Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patientstreatment3completed
NCT02320981
Mucosal Impedance in Pediatric PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT03367195
Efficacy and Safety of DLBS2411 in the Management of GERDtreatment3terminated
NCT01286155
Epidemiology of Barrett's Esophagus: A Population Based StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03561090
A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)No drug interventionstreatment3terminated
NCT02616302
A Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Childrentreatment2recruiting
NCT00171483
Assessment of the Role of Tegaserod Therapy in the Management of Gastroesophageal Reflux Disease (GERD) Symptoms in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs).treatment3completed
NCT00658528
Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT02141711
TAK-438 - Safety, Blood Levels & Effects of Repeated Dosesbasic_science1completed
NCT04506593
Indiana University Gastrointestinal Motility Diagnosis RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT00795093
Partial Response to Proton Pump Inhibitors (PPI) Treatment: The Cost to Society and the Burden to the Patient - a Study in the USNo drug interventionsNot AvailableNot Availablecompleted
NCT00260585
Esophageal Cancer Risk RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT01940185
A Post-Approval Study of the LINX® Reflux Management SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT02555852
Proton Pump Inhibitors and Risk of Community-acquired PneumoniaNot AvailableNot Availablecompleted
NCT00261300
Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)treatment3completed
NCT00468559
Phase 3/Safety & Efficacy of Esomeprazole in Infantstreatment3completed
NCT04130659
Study to Evaluate the Performance and Safety of the MARIAL® in Association With PPI Versus PPI AlonetreatmentNot Availablerecruiting
NCT00628342
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)treatment4completed
NCT01570842
Anthropometry in Gastroesophageal Reflux Disease and Esophageal InjuryNo drug interventionsbasic_scienceNot Availablecompleted
NCT02689999
The Effect of Dexrabeprazole on Intragastric and Intraesophageal Aciditytreatment4completed
NCT00312806
Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)treatment3completed
NCT01129713
Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.treatment1 / 2unknown_status
NCT00171418
Assessment of the Effects of Tegaserod in the Management of Gastroesophageal Reflux Disease (GERD) in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs).treatment3completed
NCT01647958
The EndoGastric Solutions TEMPO TrialNo drug interventionstreatmentNot Availablecompleted
NCT01324986
A Study on the Effectiveness of Laparoscopic Fundoplication on Extraesophageal Manifestations of Gastroesophageal Reflux Disease (GERD)No drug interventionsNot AvailableNot Availablecompleted
NCT01025739
Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERDNo drug interventionstreatment2withdrawn
NCT00574925
Study to Assess Management Strategies for the Use of Esomeprazole (Nexium) in Helicobacter Pylori Infected Patientstreatment4completed
NCT00838526
Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)treatment3completed
NCT00747526
A Study of Single and Multiple Doses of Rabeprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Months Old, Inclusivetreatment1completed
NCT01374074
Racial Disparity in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT00228527
Esomeprazole for Treatment of GERD in Pediatric Patientstreatment4completed
NCT02699060
Experimental Study to Determine the Effects of Human Refluxate on Macrophage Phenotype and Its Correlation With GERDNo drug interventionsotherNot Availablecompleted
NCT02318862
Assessment of Esophageal Epithelium Integrity With Mucosal ImpedanceNo drug interventionsdiagnosticNot Availablecompleted
NCT01389401
Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux LaryngitisNot AvailableNot Availablecompleted
NCT00394472
Symptom Improvements in Gastroesophageal Reflux Disease (GERD) Patientstreatment2completed
NCT02366169
Medigus Ultrasonic Surgical Endostapler (MUSE) RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT01406210
RESULT (REflux Surgery in Lung Transplantation) Preliminary Study ProtocolNo drug interventionsNot AvailableNot Availablecompleted
NCT04335734
Influence of Wrap Fixation Technique on the Results of FundoplicationNo drug interventionstreatmentNot Availablecompleted
NCT05129670
Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing GumNo drug interventionstreatmentNot Availablecompleted
NCT01710995
A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditionstreatment1completed
NCT02288988
Minimally Invasive Collis-Nissen for the Treatment of Short EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT06613438
Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) SymptomsNo drug interventionstreatmentNot Availablerecruiting
NCT00833573
National Survey on GERD Patients (Adults and Children)No drug interventionsNot AvailableNot Availablecompleted
NCT06664008
The Effect of Probiotic and Zinc Supplementation in Patients With Gastroesophageal Reflux Diseasetreatment4not_yet_recruiting
NCT06615856
The Influence of Concomitant Irritable Bowel Syndrome on Gastro-Oesophageal Reflux Disease Symptoms and Severity.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01507298
Physical Activity and Gastrointestinal InvestigationsNo drug interventionsNot AvailableNot Availablecompleted
NCT06317675
Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux DiseaseNo drug interventionstreatment2recruiting
NCT00384592
PPI Sequencing Studytreatment4completed
NCT03793556
Evaluation of GERDOFF Efficacy in Combination With Proton Pump InhibitortreatmentNot Availablecompleted
NCT03270722
Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble SwallowingNo drug interventionsdiagnosticNot Availablewithdrawn
NCT06151067
Important Correlation Between Anxiety and Reflux Symptoms in Patients With Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02505945
The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Diseasetreatment4completed
NCT06495606
"The Voice of Reflux" - Backflow of Gastric Juice Leads to Irritation of the Vocal Folds: Are There Typical Differences in the Voice?No drug interventionsNot AvailableNot Availablerecruiting
NCT04408105
Survey Study on Barrett's Esophagus ScreeningNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04711655
Antireflux Ablation of the Cardia Mucosa vs Placebo for the Treatment of Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00521703
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Childrentreatment3completed
NCT01020890
Prevalence of Gastroesophageal Reflux Disease in Primary Care Patients With Upper Gastrointestinal SymptomsNo drug interventionsNot AvailableNot Availablecompleted
NCT00255190
Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat Heartburntreatment3completed
NCT01078064
Gastric Accommodation and Gastroesophageal RefluxNo drug interventionsNot AvailableNot Availableterminated
NCT02500264
The Effect of Non Invasive Electrical Stimulation Therapy on Gastroesophageal Reflux Disease (GERD) Symptoms - Proof of Concept StudyNo drug interventionstreatmentNot Availableunknown_status
NCT00304421
Comparison of the Nighttime Effects of Two Different Drugs on Subjects With GERDtreatment4completed
NCT06319521
Stellate Ganglion Block on Gastroesophageal Reflux DiseasetreatmentNot Availablenot_yet_recruiting
NCT01161602
A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of Pumosetrag in Patients With Gastroesophageal Reflux Disease (GERD)Not Available2completed
NCT01642602
Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescentstreatment2completed
NCT04094402
Epi-GERD Study: Epidemiological Evaluation in Patients With Gastro-Esophageal Reflux Disease (GERD)No drug interventionsNot AvailableNot Availableunknown_status
NCT00321984
Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Gastroesophageal Reflux Diseasetreatment3completed
NCT02793479
Radiofrequency Ablation in Patients With Barrett's EsophagusNo drug interventionsNot AvailableNot Availableunknown_status
NCT01199679
Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)No drug interventionstreatmentNot Availableterminated
NCT04494243
A Study to Compare PK, PD and Safety of the AD-214 10/600mg and Rabeprazoletreatment1completed
NCT01641887
Decision Aid for Gastroesophageal Reflux Disease ManagementNo drug interventionsNot AvailableNot Availableunknown_status
NCT05365087
Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06481787
Zuojin Wan Combined With Woonosan Fumarate for the Treatment of GRD Combined With DepressionNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT05216133
Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01095133
Do Acid Sensing Ion Channels Contribute to Heartburn?treatment1completed
NCT02384551
Dietary Carbohydrate and GERD in VeteransNo drug interventionstreatmentNot Availablecompleted
NCT00591877
A Study to Evaluate the Role of Alternative Medicine in Difficult to Treat GERD PatientsNo drug interventionstreatmentNot Availablewithdrawn
NCT01338077
Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Diseasetreatment3completed
NCT01742377
Minimal Change Esophagitis by i-Scan Endoscopy in Dyspeptic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00507377
Foreshortened Esophagus and Its Surgical TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00637845
Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)treatment4completed
NCT01400945
Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Diseasetreatment3completed
NCT00251745
Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat Heartburntreatment3completed
NCT00674245
Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD.treatment2 / 3completed
NCT00378898
Feasibility of Placing Bravo PH Capsule in Proximal EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT00476398
Evaluation of Patients With Non-cardiac Chest PainNo drug interventionsdiagnostic4completed
NCT04152798
Approach to Hiatal Hernia Repair Based on Collagen StudyNo drug interventionstreatmentNot Availablecompleted
NCT01041105
Gastric Bypass After Previous Anti-reflux SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT01215305
A Cross-sectional Study on the Prevalence and Extraesophageal Symptoms of Gastroesophageal Reflux Disease(GERD) in Patients With Upper GI Symptoms, Visiting the Outpatient Departments of Peripheral Hospitals in GreeceNo drug interventionsNot AvailableNot Availablecompleted
NCT00734097
A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI)treatment4completed
NCT04696783
The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarersprevention3unknown_status
NCT00343161
Symptom Adapted Therapy in GERD Patientstreatment4completed
NCT00174928
A Study to Evaluate the Effect of Lansoprazole on Hospitalized Neonates With Gastroesophageal Reflux Diseasetreatment1completed
NCT01753128
Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburntreatment3completed
NCT01110811
Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)No drug interventionstreatmentNot Availablecompleted
NCT04763993
Reflux Disease After Gastric Bypass Versus Sleeve Gastrectomy in Morbid Obese Patients: an Italian StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02759393
Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitistreatment4unknown_status
NCT01504971
Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux DiseaseNot AvailableNot Availableunknown_status
NCT01882088
Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERDtreatment4completed
NCT03516188
Efficacy of Gaviscon-Advance® in Suppressing Post-supper Acid-pocket and Night-time Acid-reflux in Obese Participantstreatment2 / 3completed
NCT00480285
A Prospective Randomized Trial Comparing Laparoscopic Nissen Against Anterior Partial Fundoplication in Treating Gastroesophageal Reflux Disease Among Chinese PatientsNo drug interventionstreatment3unknown_status
NCT01043185
A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experiencetreatment2completed
NCT00830115
Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep DisordersNot AvailableNot Availablecompleted
NCT01404832
The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitorsdiagnostic4terminated
NCT00251732
Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI)treatment4completed
NCT00214552
Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma.prevention3completed
NCT02934152
Symptom Assessment for Patients With Gastro-esophageal Reflux Disease Receiving Helicobacter Pylori Eradicationtreatment4unknown_status
NCT02336100
Diagnostic Value of Flexible Spectral Imaging Color Enhancement (FICE) Plus Probe-based Confocal Laser Endomicroscopy (pCLE) for Minimal Change Esophageal Reflux Disease (MERD) DiagnosisNo drug interventionsdiagnosticNot Availablecompleted
NCT02060500
Cardiaplication: A Novel Antireflux OperationNo drug interventionstreatmentNot Availablecompleted
NCT04595500
Relationship Between Gastroesophageal Reflux Disease and Dental ErosionNo drug interventionsNot AvailableNot Availablecompleted
NCT01027975
Comparison of Laparoscopic Nissen Versus Thal Fundoplication in ChildrenNo drug interventionstreatmentNot Availablecompleted
NCT00584675
Nasopharyngeal 24 Hour pH Monitoring in Health Adult VolunteersNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01058070
An Observational Clinical Feasibility Study of the Magnetic Esophageal SphincterNo drug interventionstreatmentNot Availablecompleted
NCT00954070
Detection of Minimal Change Esophagitis Using Confocal Laser EndomicroscopyNo drug interventionsNot AvailableNot Availableterminated
NCT01818570
A Study of Local Effect and Safety of a Single PPC-5650 Dose on Reflux Pain During Pain Stimulation in the EsophagusNo drug interventionstreatment1completed
NCT01578642
Feasibility Study for Evaluating the Effect of Electrical Stimulation on Lower Esophageal Sphincter Pressure and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux DiseaseNo drug interventionstreatment2completed
NCT00200642
Evaluation of the Efficiency of Radiofrequency in the Treatment of Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04036942
Antireflux Ablation Therapy (ARAT) Vs Antireflux Mucosectomy (ARMS) In The Management Of Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT00730106
Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) SymptomsNo drug interventionsNot AvailableNot Availablecompleted
NCT03037606
Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tabletstreatment4completed
NCT01065649
Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patientstreatment3completed
NCT03128736
Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and Btreatment4completed
NCT00449813
The CONQUEST-Study. Evaluation of Clinical Endpoints for Treatment-induced Changes in GERD-related Symptoms (BY1023/NL511)treatment4terminated
NCT00220818
A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease.treatment1completed
NCT00165841
Maintenance Intermittent Therapy for Symptomatic GERD Patientstreatment2completed
NCT04311541
A Study of Dexlansoprazole Modified Release (MR) in Gastroesophageal Reflux Disease (GERD) Participants in the Russian FederationNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01126034
Improving Metoclopramide Prescribing Practices at Penn Through a Physician-targeted InterventionNo drug interventionsNot AvailableNot Availablecompleted
NCT01696734
Domperidone in Treating Patients With Gastrointestinal Disorderstreatment3recruiting
NCT02860624
Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patientstreatment3completed
NCT03223116
Radiofrequency Energy Delivery for Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT05405816
Determination of Change in Reflux Disease After Sleeve Gastrectomy by Intraluminal Impedance and pH-meterNo drug interventionsdiagnosticNot Availablecompleted
NCT00132496
Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With Rabeprazoletreatment2completed
NCT01489735
The Use of International GerdQ QuestionnaireNo drug interventionsNot AvailableNot Availablecompleted
NCT02486263
Neonatal Gastro-Esophageal Reflux Disease (GERD) Management TrialNo drug interventionstreatmentNot Availablecompleted
NCT03069963
PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjectsbasic_science1completed
NCT01921686
Morphological Markers of Gastroesophageal Reflux Disease (GERD)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01574339
Effect of Long-Term Electrical Stimulation on LES Pressure and Esophageal Acid Exposure in Patients With GERDNo drug interventionstreatment3unknown_status
NCT01472939
Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment2completed
NCT00165022
Development of a Novel Disease-Specific Quality of Life Questionnaire for Gastroesophageal Reflux Disease (GERD) Patients in Chinese PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT01471925
Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBICtreatment3withdrawn
NCT00561730
Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD)Not AvailableNot Availablecompleted
NCT02984930
Effect of Proton Pump Inhibitor and Mosapride on Acid Pocket in Gastroesophageal Reflux DiseasetreatmentNot Availableunknown_status
NCT01536457
Reflux Disease Therapy in the Management of Childhood Asthma-data Entry and Analysis OnlyNo drug interventionsNot AvailableNot Availablecompleted
NCT03871426
Manual Therapy Effects on Upper and Lower Esophageal Sphincter PressuresNo drug interventionsNot AvailableNot Availablecompleted
NCT01878526
Gastroesophageal Reflux Treatment in Sclerodermatreatment3completed
NCT01682265
Stretta In Reflux Uncontrolled by IPPNo drug interventionstreatmentNot Availablecompleted
NCT00324974
The Use of Lansoprazole to Treat Infants With Symptoms of Gastroesophageal Refluxtreatment3completed
NCT01572974
Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availableterminated
NCT06348420
Anti-reflux Mucosal Valvuloplasty Versus PPIs for GERD TreatmentNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00498082
Determinants of Efficacy of EsophyX Treatment in Gastro-Esophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01249482
Symptom Assessment for GERD Patients Receiving H. Pylori EradicationNo drug interventionsNot AvailableNot Availableunknown_status
NCT01479231
Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitistreatment1 / 2withdrawn
NCT01580631
Narrow Band Imaging Project on Barrett's EsophagusNo drug interventionsNot AvailableNot Availablesuspended
NCT01776827
Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University HospitalNo drug interventionsNot AvailableNot Availablecompleted
NCT00926276
The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary DysplasiaNo drug interventionstreatment4completed
NCT00660660
Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study UStreatment4completed
NCT02579460
Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-TransitionNo drug interventionsbasic_scienceNot Availablecompleted
NCT02351960
Dexlansoprazole in Asian Participants With Gastroesophageal Reflux Diseasetreatment4completed
NCT03848494
True Short Esophagus in Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01381991
The Efficacy of i-Scan for Detecting Reflux EsophagitisNo drug interventionsdiagnosticNot Availablecompleted
NCT01710462
Clinical Study, Multicenter, Randomized With 2 Arms of Pantoprazole + Domperidone and Pantoprazole Isolated at the Gastroesophageal Reflux Diseasetreatment3withdrawn
NCT02923362
Registry of Outcomes From AntiReflux SurgeryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01136980
Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT StudyNo drug interventionstreatmentNot Availablecompleted
NCT05452980
Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT00410592
Evaluation of 24-Hour Intragastric pH Using Esomeprazole, Lansoprazole, and Pantoprazole in Hispanic Patients With GERDtreatment4completed
NCT01432392
Symptom Control and Impact on Daily Life in Patients With Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00998244
Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00200044
An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)No drug interventionstreatmentNot Availableterminated
NCT00963144
Diagnosis and Response to Treatment Using a Reliable Gastroesophageal Reflux Disease (GERD) Questionnaire: An In Clinical Practice StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00539240
Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPItreatment2 / 3completed
NCT00164840
Symptomatic Gastroesophageal Reflux Disease: Double Blind Randomized Controlled Study of On-demand Therapy Versus Maintenance Therapytreatment3completed
NCT05701540
A Study to Evaluate the Efficacy and Safety of Tegoprazan in GERD Patients With Nighttime Heartburntreatment4recruiting
NCT01777867
Cough Reflex Sensitivity and Bronchial Hyper-responsivenessNo drug interventionsNot AvailableNot Availablecompleted
NCT01954667
Anthropometric Measures and Severity of Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06153901
Endoloop Mediated Cardioplication to Treat Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02457104
The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43No drug interventionsNot AvailableNot Availableunknown_status
NCT05422404
Anti-Reflux Mucosal Ablation(ARMA) and Anti-Reflux Mucosectomy(ARMS) in Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00901004
The Clinical Significance of Minimal Change in Reflux Esophagitis Based on the Gastroesophageal Reflux Disease QuestionnaireNo drug interventionsNot AvailableNot Availablecompleted
NCT01634672
Prevalence of Gastroesophageal Reflux Disease in Peritoneal Dialysis and Hemodialysis PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04703868
A Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of YPI 011 to Rabeprazole in Healthy Adult Subjectstreatment1completed
NCT03776669
Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT05514769
Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric CancerNo drug interventionstreatmentNot Availablerecruiting
NCT02958046
The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Aciditytreatment4completed
NCT01733810
The Role of HIF-2a in the Pathogenesis of Reflux EsophagitisNo drug interventionsbasic_scienceNot Availablecompleted
NCT01149395
Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburnbasic_science1completed
NCT00786695
Study Using Esomeprazole as a Diagnostic Test for GERD in Patients With NCCPdiagnosticNot Availablecompleted
NCT00872755
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment4completed
NCT01262755
Temple Registry for the Investigation of African American Gastrointestinal Disease EpidemiologyNo drug interventionsNot AvailableNot Availablecompleted
NCT02685150
Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux DiseasediagnosticNot Availablecompleted
NCT01107938
Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patientstreatment2unknown_status
NCT02706938
Impact of Head of Bed Elevation in Symptoms of Patients With Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00829738
Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux DiseaseNot AvailableNot Availablecompleted
NCT01026103
Tri Staple Technology Stapler Used in Gastric BypassNo drug interventionstreatmentNot Availablecompleted
NCT00684190
Drug Interaction Study Between AZD3355 and Nexiumbasic_science1completed
NCT00564590
SThe Effects of Melatonin on GERD Symptomstreatment1 / 2unknown_status
NCT00688402
Study to Compare Different Formulations of AZD3355basic_science1completed
NCT02890979
Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux DiseaseNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT05886933
Study to Evaluate the Efficacy and Safety of FEXUCLUE TabletNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01005251
Investigate the Effect of Different Doses of Lesogaberan (AZD3355) as add-on to PPI in GERD Patients With Partial Response to PPItreatment2completed
NCT00393653
Prescription Methods Assessment Project (PMAP)No drug interventionstreatmentNot Availableterminated
NCT03284177
A Trial of C13-CAC Breath Test in PPI Resistant GERD PatientsNo drug interventionsdiagnostic2completed
NCT00217347
Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper EndoscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT02072447
Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose StudyNo drug interventionsbasic_science0completed
NCT02211105
Registry to Compare Two Surgical Treatments for GERDNo drug interventionsNot AvailableNot Availableterminated
NCT01872897
Compound Sodium Alginate Double Action Chewable Tablets 4-hour Esophageal pH Study in GERD Patientstreatment3completed
NCT00886197
Diagnostic Efficacy of Narrow Band Imaging in Patients With Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00928161
Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation TherapytreatmentNot Availablewithdrawn
NCT00951093
Gastroesophageal Reflux Disease (GERD) Before and After Gastric BypassNo drug interventionsNot AvailableNot Availablecompleted
NCT02255071
The Efficacy of Neiguan (P6 Point) Acupressure in Patients With Gastroesophageal Reflux Disease (GERD)No drug interventionssupportive_careNot Availableunknown_status
NCT00698178
Waist Circumference Versus Body Mass Index to Predict Severity of Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02135107
A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patientstreatment3completed
NCT02818309
Lesogaberan in Chinese Patients With Refractory Reflux Symptomstreatment2unknown_status
NCT03053609
Gastroesophageal Reflux and Cardiorespiratory ProblemsNo drug interventionsNot AvailableNot Availablecompleted
NCT02893709
Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)basic_scienceNot Availablecompleted
NCT00414856
Effects of AFQ056 and Baclofen on Meal-Induced Gastroesophageal Refluxtreatment1completed
NCT01118585
Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD)No drug interventionstreatmentNot Availablecompleted
NCT01053585
Structure and Function of the Gastro-esophageal JunctiondiagnosticNot Availablecompleted
NCT03299985
Diaphragmatic Myofascial Release in Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01453985
Full-Thickness-Gastroplication For The Treatment Of Gastroesophageal Reflux Disease GERDNo drug interventionsNot AvailableNot Availableunknown_status
NCT01391715
Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERDtreatment3withdrawn
NCT01642615
Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescentstreatment2completed
NCT05614752
Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE TabNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02186652
PK Study With Pantoprazole in Obese Children and Adolescentsbasic_science1completed
NCT06106100
Anti-reflux Mucosal Ablation Therapy Randomized Sham Control Trial for Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01089959
Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERDtreatment2 / 3unknown_status
NCT02154659
The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux SymptomsNo drug interventionsdiagnosticNot Availablecompleted
NCT06304142
Effect of Lidocaine Block on Gastroesophageal Reflux DiseasetreatmentNot Availablenot_yet_recruiting
NCT00914342
Prevalence and Impact in Work Productivity of Gastroesophageal Reflux Disease (GERD) in Primary Care Patients With Upper Gastrointestinal (GI) Symptoms Using GerdQNo drug interventionsNot AvailableNot Availablecompleted
NCT06215742
Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablewithdrawn
NCT01822106
Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment4unknown_status
NCT02558049
Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision AidNo drug interventionsotherNot Availablecompleted
NCT02685436
Role of Pepsin Assay in Wheezy Infantsdiagnostic4completed
NCT01782118
LGG for Prevention of Infectious Complications During PPI Treatment in ChildrenNo drug interventionsprevention4unknown_status
NCT00405119
A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.diagnostic2completed
NCT05107219
GCC Agonist Signal in the Small Intestineprevention1recruiting
NCT03616119
Gastroesophageal Reflux Disease in AzerbaijanNo drug interventionsNot AvailableNot Availablecompleted
NCT06504134
Gastroesophageal Reflux Disease Diagnostic TrialNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02930824
Genotype-supported Versus Conventional Proton Pump Inhibitor DosingNo drug interventionsscreeningNot Availablecompleted
NCT00915616
The Potential Therapeutic Effect of Melatonin in Gastro-Esophageal Reflux Diseasetreatment3withdrawn
NCT00978016
A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)treatment2completed
NCT03065816
Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjectsbasic_science1completed
NCT00768196
Prevalence of EED and Quality of Life Evaluated by Gastroesophageal Reflux Disease (GERD)-Q in Korean GERD PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01039558
The Effect of Lansoprazole in Combination With Ecabet Sodium for Gastroesophageal Reflux DiseasetreatmentNot Availablecompleted
NCT00251758
Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Heartburntreatment3completed
NCT04622358
A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazoletreatment1completed
NCT02096458
Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tabletstreatment1completed
NCT00858858
Clinical Studies on Bile Acids in Barrett's Esophagusbasic_scienceNot Availablecompleted
NCT02401035
PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric Subjectstreatment4terminated
NCT01212835
Effect of RING on Gastroesophageal Reflux (GERD) After RYGBPNo drug interventionstreatmentNot Availableterminated
NCT01099735
Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01370863
An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD PatientsNo drug interventionstreatment2terminated
NCT00539786
The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERDdiagnosticNot Availableunknown_status
NCT02277886
Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbancestreatment4unknown_status
NCT00729339
Role of Mosapride in Patients With Gastroesophageal Reflux DiseaseNo drug interventionstreatment4completed
NCT00492622
Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesistreatment4completed
NCT05660122
A Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE TabNo drug interventionsNot AvailableNot Availablerecruiting
NCT06106022
A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Diseasetreatment1completed
NCT02637557
A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment2completed
NCT05193266
Gastroesophageal Reflux Disease (GERD) Among ICU SurvivorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00730665
Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)treatment2terminated
NCT00057174
Economic Impact of Guidelines for Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01806220
Laryngeal and Esophageal EGF-r Expression in Patients With Reflux LaryngitisNo drug interventionsdiagnosticNot Availablecompleted
NCT01128582
Effect of Rozerem on the Perception of GERD Symptoms in Patients With Chronic Insomnia.treatment3unknown_status
NCT01204931
Can We Predict Who Has Gastroesophageal Reflux Disease (GERD)?No drug interventionsNot AvailableNot Availablecompleted
NCT00786773
Survey to Describe Impact of Reflux Disease on Everyday Life in GERD Patients Before and After 4 Weeks Treatment.No drug interventionsNot AvailableNot Availablecompleted
NCT00551473
Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg.diagnostic1completed
NCT00574327
Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT00325676
Comparison of the Classical Healing Concept With the Complete Remission Concept After Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342)treatment4completed
NCT05062876
A Study to Compare PK, PD and Safety of the AD-214 and AD-2141treatment1completed
NCT06585176
Epidemiological Studies and Risk Factor Analysis of GERD in Xiamen CityNo drug interventionsNot AvailableNot Availablerecruiting
NCT01321294
Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT01324791
Laparoscopic Antireflux Surgery Versus Endoscopic Full-thickness Gastroplication for Gastroesophageal Reflux Disease (GERD)No drug interventionsNot AvailableNot Availablecompleted
NCT01869491
Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Studytreatment3completed
NCT00626262
Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and ivtreatment4completed
NCT00206180
NEXIUM® in the Treatment of Moderate and Severe Erosive EsophagitisNot Available4completed
NCT04306380
Transoral Incisionless Fundoplication Database Repository (TIF)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02100189
Esophageal Cytology With FISH in Detecting Esophageal CancerNo drug interventionsscreeningNot Availablecompleted
NCT01576289
Analysis of Biopsies From the Upper Gastrointestinal TractNo drug interventionsNot AvailableNot Availablecompleted
NCT02873689
Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patientstreatment3completed
NCT01844440
Diagnostic of Transient Lower Esophageal Sphincter Relaxation With Combined Impedance and High Resolution Manometry in Patients With GERDNo drug interventionsdiagnosticNot Availablecompleted
NCT00272701
Esomeprazole in PPI Failures - IMPROVEtreatment4completed
NCT05937204
Nursing Teaching Scheme for Patients With Gastroesophageal Reflux DiseaseNo drug interventionsotherNot Availablenot_yet_recruiting
NCT04568772
Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteersother1completed
NCT00260572
Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03853772
The Johns Hopkins Heartburn Center RegistryNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03068572
Diagnostic Value of Linked Color Imaging for Minimal Change Esophagitis in Nonerosive Reflux Esophagitis and GERDNo drug interventionsNot AvailableNot Availableunknown_status
NCT03904472
Cognitive Behavioral Therapy for Insomnia (CBTI) in GERD Patients With InsomniaNo drug interventionstreatmentNot Availablecompleted
NCT05647668
Laparoscopic Total vs Partial Fundoplication in Patients With Atypical Symptoms of Gastroesophageal Reflux DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00885469
PillCam® ESO 2 in Esophageal PathologiesNo drug interventionsNot AvailableNot Availablecompleted
NCT02039869
Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)diagnosticNot Availablewithdrawn
NCT01798212
Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD.No drug interventionstreatmentNot Availablecompleted
NCT00287612
Necessity of Esophageal Dissection During Laparoscopic FundoplicationNo drug interventionstreatmentNot Availablecompleted
NCT04052581
Prospective Collection of Outcome Data Post POEM-TIF ProcedureNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00625495
Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)treatment4completed
NCT01212614
Measurement of Gastric Secretion by MRI Under Inhibition by ProtonPump Inhibitors in Healthy Subjects & in GERD PatientsNo drug interventionstreatmentNot Availablecompleted
NCT01390714
Pharmacodynamic and Pharmacokinetic Study of E3710 Following Oral Administration to Healthy, Male, Japanese SubjectsNo drug interventionstreatment1completed
NCT00842855
Partial Response to PPI Treatment: The Cost to Society and the Burden to the Patient - a Study in FranceNo drug interventionsNot AvailableNot Availablecompleted
NCT02200055
Using Electrical Bioimpedance Assessments to Estimate Perioperative Total Body Water and Postoperative Fluid NeedNo drug interventionsdiagnosticNot Availablecompleted
NCT03692455
Clinico-functional Evaluation of GERD: Comparative Study of Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric BypassNo drug interventionstreatmentNot Availablecompleted
NCT00618150
Patient Education in Gastroesophageal Reflux DiseaseNo drug interventionshealth_services_researchNot Availablecompleted
NCT01200550
The Study to Describe Symptom Control and Impact on Daily Life in Gastroesophageal Reflux Disease (GERD) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04129008
GaStroEsophageal effeCt of indobUfen Versus aspiRin in Patients Undergoing Dual antiplatElet Therapytreatment4unknown_status
NCT01128608
The Effect of High PCO2 Solution on Esophageal Acid SensationNo drug interventionsdiagnosticNot Availableunknown_status
NCT03467438
Efficacy of Zinc L-carnosine in Maintaining Remission of Gastroesophageal Reflux Diseasetreatment4unknown_status
NCT00768443
Symptoms and Management Strategies in Gastroesophageal Reflux Disease (GERD)No drug interventionsNot AvailableNot Availablecompleted
NCT01057992
A Prospective Evaluation of the Torax Medical Inc. Magnetic Esophageal SphincterNo drug interventionstreatment1 / 2completed
NCT01058564
A Prospective Evaluation of the Torax Medical Inc. Magnetic Esophageal SphincterNo drug interventionstreatment1 / 2completed