Avagacestat

DB11893InvestigationalSmall molecule

Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.

Chemical structure of Avagacestat
Formula / weight
C20H17ClF4N4O4S · 520.88 g/mol (avg)
Code names
BMS-708163

Resolves to

Compound
UNIITQ44WWY45QCAS1146699-66-2ChEMBLCHEMBL1090771PubChem46883536
Structure
InChIKeyXEAOPVUAMONVLA-QGZVFWFLSA-NSMILESNC(=O)[C@@H](CCC(F)(F)F)N(CC1=CC=C(C=C1F)C1=NOC=N1)S(=O)(=O)C1=CC=C(Cl)C=C1
Targets
P49768PSEN1Q92542NCSTNQ9NZ42PSENENQ8WW43APH1BQ96BI3APH1A

What you can answer from here — as of January 29, 2025

5Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
7Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Avagacestat, and which of those have an active Phase 3 trial?

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